Circular YAC vectors containing short mammalian origin sequences are maintained under selection as HeLa episomes

Journal of Cellular Biochemistry

Volumn 76, Issue 4, 2000, Pages 674-685

  Nielsen, Torsten O ^a   Cossons, Nandini H ^b   Zannis Hadjopoulos, Maria ^b   Price, Gerald B ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Artificial chromosome; Autonomous replication; DNA replication; Episome; Human; Replication origin

Indexed keywords

ARTICLE; CHROMOSOME STRUCTURE; CLONING VECTOR; DNA REPLICATION; DNA REPLICATION ORIGIN; EPISOME; HUMAN; HUMAN CELL; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

BROMODEOXYURIDINE; CELL DIVISION; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 6; CLONING, MOLECULAR; DNA REPLICATION; DNA, CIRCULAR; GENES, BACTERIAL; GENES, FUNGAL; GENETIC VECTORS; GENTAMICINS; HELA CELLS; HUMANS; PLASMIDS; REPLICATION ORIGIN; TRANSFECTION; TRANSFORMATION, GENETIC;

BACTERIA (MICROORGANISMS); CRICETINAE; MAMMALIA;

EID: 0033974502     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(20000315)76:4<674::AID-JCB15>3.0.CO;2-2     Document Type: Article

References (35)

1. Bell D, Sabloff M, Zannis-Hadjopoulos M, Price GB. 1991. Anti-cruciform DNA affinity purification of active mammalian origins of replication. Biochim Biophys Acta 1089: 99-308.
2. Burhans WC, Vassilev LT, Caddle MS, Heintz NH, De-Pamphilis ML. 1990. Identification of a bidirectional DNA replication origin in mammalian chromosomes. Cell 62:955-965.
3. Cossons N, Nielsen T, Dini C, Tomilin N, Young DB, Riabowol KT, Rattner JB, Johnston RN, Zannis-Hadjopoulos M, Price GB. 1997. Circular YAC vectors containing small mammalian origin sequences can associate with the nuclear matrix. J Cell Biochem 67:439-450.
4. Dani GM, Zakian VA. 1983. Mitotic and meiotic stability of linear plasmids in yeast. Proc Natl Acad Sci USA 80:3406-3410.
5. DePamphilis ML. 1993. Eukaryotic DNA replication: anatomy of an origin. Annu Rev Biochem 62:29-63.
6. Featherstone T, Huxley C. 1993. Extrachromosomal maintenance and amplification of yeast artificial chromosome DNA in mouse cells. Genomics 17:267-278.
7. Frappier L, Zannis-Hadjopoulos M. 1987. Autonomous replication of plasmids bearing monkey DNA origin-enriched sequences. Proc Natl Acad Sci USA 84:6668-6672.
8. Gassman M, Donoho G, Berg P. 1995. Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells. Proc Natl Acad Sci USA 92:1292-1296.
9. Hahnenberger KM, Baum MP, Polizzi CM, Carbon J, Clarke L. 1989. Construction of artificial minichromosomes in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci USA 86:577-581.
10. Hamlin JL, Mosca PJ, Levenson W. 1994. Defining origins of replication in mammalian cells. Biochim Biophys Acta 1198:85-111.
11. Hanish JP, Yanowitz JL, de Lange T. 1994. Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci USA 91:8861-8865.
12. Harrington JJ, Van Bokkelen G, Mays RW, Gustashaw K, Willard HF. 1997. Formation of de novo centromeres and construction of first generation human artificial chromosomes. Nature Genet 15:345-355.
13. Hirt B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol 26:365-369.
14. Hollo G, Kereso J, Praznovsky T, Cserpan I, Fodor K, Katona R, Csonka E, Fatyol K, Szeles A, Szalay AA, Hadlaczky G. 1996. Evidence for a megareplicon covering megabases of centromeric chromosome segments. Chrom Res 4:1-14.
15. Huxley C. 1994. Mammalian artificial chromosomes: a new tool for gene therapy. Gene Ther 1:7-12.
16. Krysan PJ, Haase SB, Calos MP. 1989. Isolation of human sequences that replicate autonomously in human cells. Mol Cell Biol 9:1026-1033.
17. Landry S, Zannis-Hadjopoulos M. 1991. Classes of autonomously replicating sequences are found among early replicating monkey DNA. Biochim Biophys Acta 1088: 234-244.
18. Luria SE, Delbrück M. 1943. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28:491-511.
19. McWhinney C, Leffak M. 1990. Autonomous replication of a DNA fragment containing the chromosomal replication origin of the human c-myc gene. Nucleic Acids Res 18: 1233-1242.
20. McWhinney C, Waltz SE, Leffak M. 1995. Cis-acting effects of sequences within 2.4 kb upstream of the human c-myc gene on autonomous plasmid replication in HeLa cells. DNA Cell Biol 14:565-579.
21. Murray AW, Szostak JW. 1983. Construction of artificial chromosomes in yeast. Nature 305:189-193.
22. Nielsen T, Bell D, Lamoureux C, Zannis-Hadjopoulos M, Price GB. 1994. A reproducible method for identification of human genomic DNA autonomously replicating sequences. Mol Gen Genet 242:280-288.
23. Pelletier R, Price GB, Zannis-Hadjopoulos M. 1999. Functional genomic mapping of an early-activated centromeric mammalian origin of DNA replication. J Cell Biochem 74:562-575.
24. Radloff R, Bauer W, Vinograd J. 1967. A dye-buoyant density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells. Proc Natl Acad Sci USA 57:1514-1521.
25. Schiestl RH, Petes TD. 1991. Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 88:7585-7589.
26. Shihab-El-Deen A, Wu C, Hamerton JL, Zannis-Hadjopoulos M, Price GB. 1993. Chromosomal localization of a sequence with in vivo activity for initiation of DNA replication. Somat Cell Mol Genet 19:103-109.
27. Simpson K, McGuigan A, Huxley C. 1996. Stable episomal maintenance of yeast artificial chromosomes in human cells. Mol Cell Biol 16:5117-5126.
28. Strauss WM. 1989. Preparation of genomic DNA from mammalian tissue. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors. Short protocols in molecular biology. New York: John Wiley & Sons, p 59.
29. Stinchcomb DT, Struhl K, Davis RW. 1979. Isolation and characterisation of a yeast chromosomal replicator. Nature 282:39-43.
30. Sun TQ, Fenstermacher DA, Vos JMH. 1994. Human artificial episomal chromosomes for cloning large DNA fragments in human cells. Nature Genet 8:33-41.
31. Szostak JW, Blackburn EH. 1982. Cloning yeast telomeres on linear plasmid vectors. Cell 29:245-255.
32. Traver CN, Klapholz S, Hyman RW, Davis RW. 1989. Rapid screening of a human genomic library in yeast artificial chromosomes for single-copy sequences. Proc Natl Acad Sci USA 86:5898-5902.
33. Wu C, Friedlander P, Lamoureux C, Zannis-Hadjopoulos M, Price GB. 1993a. cDNA clones contain autonomous replication activity. Biochim Biophys Acta 1174:241-257.
34. Wu C, Zannis-Hadjopoulos M, Price GB. 1993b. In vivo activity for initiation of DNA replication resides in a transcribed region of the human genome. Biochim Biophys Acta 1174:258-266.
35. Zannis-Hadjopoulos M, Nielsen TO, Todd A, Price GB. 1994. Autonomous replication in vivo and in vitro of clones spanning the region of the DHFR origin of bidirectional replication (oriβ). Gene 151:273-277.