Nonextrapyramidal side effects of novel antipsychotics

Current Opinion in Psychiatry

Volumn 13, Issue 1, 2000, Pages 45-50

  Wirshing, Donna A ^a,b,d   Erhart, Steven M ^a,c   Pierre, Joseph M ^b   Boyd, Jennifer A ^a  

^a VA Gtr Los Angeles Healthcare Syst ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; NEW DRUG; OLANZAPINE; PROLACTIN; QUETIAPINE; RISPERIDONE; SERTINDOLE; ZIPRASIDONE;

AUTONOMIC DYSFUNCTION; BODY MASS; CARDIOVASCULAR RISK; DIABETES MELLITUS; EXTRAPYRAMIDAL SYNDROME; FEMALE; HEART ARRHYTHMIA; HEART DISEASE; HEART MUSCLE ISCHEMIA; HUMAN; HYPERPROLACTINEMIA; HYPERTHERMIA; HYPOTENSION; IMPAIRED GLUCOSE TOLERANCE; MALE; NEUROLEPTIC MALIGNANT SYNDROME; NEUROTOXICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PSYCHOSIS; REVIEW; SEXUAL DYSFUNCTION; TACHYCARDIA; WEIGHT GAIN;

EID: 0033974168     PISSN: 09517367     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001504-200001000-00008     Document Type: Review

References (49)

1. 1 Wirshing DA, Marder SR, Wirshing WC, Saunders SC, Rossotto EH, Erhart SM. Atypical antipsychotics: a practical review. Medscape 1997; http:// www.medscape.com.
2. 2 Milou-Daniel D, Wen W, Liu XK, Woolsey RL, Flockhart DA. Prolongation of QT interval in isolated feline hearts by antipsychotic drugs. J Clin Psychopharmacol 1998; 18:477-481. This study compared QT prolongation in various antipsychotics.
3. 3 Varma S, Achan K. Dysrhythmia associated with clozapine. Aust N Z J Psychiatry 1999; 33:118-119. A case report is reported.
4. 4 Collaborative Working Group on Clinical Trial Evaluations. Adverse effects of the atypical antipsychotics. J Clin Psychiatry 1998; 59 (Suppl 12):17-22. A thorough review article of side effects is presented.
5. 5 Wirshing DA, Wirshing WC, Kysar L, Berisford MA, Goldstein D, Pashdag J, et al. Novel antipsychotics: comparison of weight gain liabilities. J Clin Psychiatry 1999; 60:358-363. A retrospective analysis of 92 patients is reported.
6. 6 Allison DB, Zannolli R, Narayan KM. The direct health care costs of obesity in the United States. Am J Public Health 1989; 89:1194-1199.
7. 7 Allison DB, Fontaine KR, Moonseong H, Mentore JL, Cappelleri JC, Chandler LP, et al. The distribution of body mass index among individuals with and without schizophrenia. J Clin Psychiatry 1999; 60:215-220. This is a large study involving over 80000 patients with schizophrenia.
8. 8 Frankenburg FR, Zanarini MC, Kando J, Centorrino F. Clozapine and body mass change. Biol Psychiatry 1998; 43:520-524. This is a prospective study involving 42 patients over 1 year.
9. 9 Briffa D, Meehan T. Weight changes during clozapine treatment. Aust N Z J Psychiatry 1998; 32:718-721. This prospective study involved 51 patients over a period of 1 year.
10. 10 Kelly DL, Robert RC, Love RC, Horn DS, Ushchak CM. Weight gain in adolescents treated with risperidone and conventional antipsychotics over six months. J Child Adolesc Psychopharmacol 1998; 8:151-159. This retrospective study included 60 patients over 6 months.
11. 11 Wirshing DA, Spellberg BJ, Erhart SM, Marder SR, Wirshing WC. Novel antipsychotics and new onset diabetes. Biol Psychiatry 1998; 44:778-783. This is a summary of six new cases, as well as a review of previous cases.
12. 12 Kamran A, Doraiswamy PM, Jane JL, Hammett EB, Dunn L. Severe hyperglycemia associated with high doses of clozapine. Am J Psychiatry 1994; 151:1395.
13. 13 Koval MS, Rames LJ, Christie S. Diabetic ketoacidosis associated with clozapine treatment. Am J Psychiatry 1994; 151:1520-1521.
14. 14 Kostakoglu AE, Yazici KM, Erbas T, Guvener N. Ketoacidosis as a side-effect of clozapine: a case report. Acta Psychiatr Scand 1996; 93:217-218.
15. 15 Peterson GA, Byrd SL. Diabetic ketoacidosis from clozapine and lithium cotreatment. Am J Psychiatry 1996; 153:737-738.
16. 16 Koren W, Kreis Y, Duchowiczny K, Prince T, Sancovici S, Sidi Y, Gur H. Lactic acidosis and fatal myocardial failure due to clozapine. Ann Pharmacother 1997; 31:168-170.
17. 17 Popli AP, Konicki PE, Jurjus GJ, Fuller MA, Jaskiw GE. Clozapine and associated diabetes mellitus. J Clin Psychiatry 1997; 58:108-111.
18. 18 Ober SK, Hudnak R, Rusterholtz A. Hyperglycemia and olanzapine. Am J Psychiatry 1999; 156:970. This is a case report involving one patient.
19. 19 Mohan D, Gordon H, Hindley N, Barker A. Schizophrenia and diabetes mellitus. Br J Psychiatry 1999; 174:180-181. This is a case report involving one patient.
20. 20 Hagg S, Joelsson L, Mjorndal T, Spigset O, Oja G, Dahlqvist R. Prevalence of diabetes and impaired glucose tolerance in patients treated with clozapine compared with patients treated with conventional depot neuroleptic medications. J Clin Psychiatry 1998; 59:294-299. This is a prospective study involving 67 patients.
21. 2c serotonin receptors. Nature 1995; 374:542-546.
22. 22 Uvnas-Moberg K, Ahlenius S, Alster P, Hillegaart V. Effects of selective serotonin and dopamine agonists on plasma levels of glucose, insulin, and glucagon in the rat. Neuroendocrinology 1996; 63:269-274.
23. 23 Petty RG. Prolactin and antipsychotic medications: mechanism of action. Schizophr Res 1999; 35:S67-S73. [supplement 35]. This is a review of the mechanisms of action of the NAPDs.
24. 24 Dickson RA, Glazer WM. Neuroleptic-induced hyperprolactinemia. Schizophr Res 1999; 35:S75-S86. [supplement 35]. This is a review of hyperprolactinemia and its consequences.
25. 25 Shiwach RS, CarmodyTJ. Prolactogenic effects of risperidone in male patients: a preliminary study. Acta Psychiatr Scand 1998; 98:81-83. This is a case report involving only one patient.
26. 26 Caracci G. Prolactin levels in premenopausal women treated with risperidone compared with those of women treated with typical neuroleptics [Letter]. J Clin Psychopharmacol 1999; 19:194-196. A letter to the editor is presented.
27. 27 Kim YK, Kim L, Lee MS. Risperidone and associated amenorrhea: a report of 5 cases. J Clin Psychiatry 1999; 60:315-317. Five detailed case reports are presented.
28. 28 Gazzola LR, Opler LA. Return of menstruation after switching from risperidone to olanzapine. J Clin Psychopharmacol 1998; 18:486-487. A letter to the editor regarding one patient is presented.
29. 29 Dickson RA, Glazer WM. Hyperprolactinemia and male sexual dysfunction. J Clin Psychiatry 1999; 60:125-. This is a case report involving one patient.
30. 30 Canuso CM, Hanau M, Jhamb KK, Green AI. Olanzapine use in women with antipsychotic-induced hyperprolactinemia. Am J Psychiatry 1998; 155:1458-. Two case reports are presented.
31. 31 Kleinberg DL, Davis JM, De Coster R, Van Baelen B, Brecher M. Prolactin levels and adverse events in patients treated with risperidone. J Clin Psychopharmacol 1999; 19:57-61. Data from randomized, double-blind studies of patients on risperidone are analyzed.
32. 32 Hummer M, Kemmler G, Kurz M, Kurzthaler I, Oberbauer H, Fleischhacker W. Sexual disturbances during clozapine and haloperidol treatment for schizophrenia. Am J Psychiatry 1999; 156:631-633. This extensive prospective study included over 150 patients.
33. 33 Deirmenjian JM, Erhart SM, Wirshing DA, Spellberg BJ, Wirshing WC. Olanzapine-induced reversible priapism: a case report. J Clin Psychopharmacol 1998; 18:351-352. A case report involving one patient is presented.
34. 34 Gordon M, De Groot CM. Olanzapine-associated priapism. J Clin Psychopharmacol 1999; 19:192. A case report involving one patient is presented.
35. 35 Nimgaonkar VL. Reduced fertility in schizophrenia: here to stay? Acta Psychiatr Scand 1998; 98:348-353. This review of the literature pertains to reproductive rates among schizophrenic patients.
36. 36 McGrath JJ, Hearle J, Jenner L, Plant K, Drummond A, Barkla JM. The fertility and fecundity of patients with psychoses. Acta Psychiatr Scand 1999; 99:441-446. This study involved fertility rates in patients with schizophrenia.
37. 37 Dickson RA, Hogg L. Pregnancy of a patient treated with clozapine. Psychiatr Serv 1998; 49:1081-1083. This is a case report involving one patient.
38. 38 Dickson RA, Dawson DT. Olanzapine and pregnancy [Letter]. Can J Psychiatry 1998; 43:196-197.
39. 39 Currier GW, Simpson GM. Antipsychotic medications and fertility. Psychiatr Serv 1998; 49:175-176. A letter to the editor is presented.
40. 40 Caroff SN, Mann SC. Neuroleptic malignant syndrome. Med Clin North Am 1993; 77:185-202.
41. 41 Levenson JL. Neuroleptic malignant syndrome. Am J Psychiatry 1985; 142:1137-1145.
42. 42 Hasan S, Buckley P. Novel antipsychotics and the neuroleptic malignant syndrome: a review and critique. Am J Psychiatry 1998; 155:1113-1116. Reported cases of NMS among patients treated with clozapine and risperidone are compared using varying diagnostic criteria.
43. 43 Karagianis JL, Phillips LC, Hogan KP, Le Drew KK. Clozapine-associated NMS: two new cases and a review of the literature. Ann Pharmacother 1999; 33:623-630. This is a review of 27 case reports of NMS, including demographic data and possible risk factors.
44. 44 Meterissian GB. Risperidone induced neuroleptic malignant syndrome: a case report and review. Can J Psychiatry 1996; 41:52-54.
45. 45 Johnson V, Bruxner G. Neuroleptic malignant syndrome associated with olanzapine. Aust N Z J Psychiatry 1998; 32:884-886. A case report is presented.
46. 46 Margolese HC, Chouinard G. Olanzapine-induced neuroleptic malignant syndrome with mental retardation. Am J Psychiatry 1999; 156:1115-1116. A case report involving one patient is presented.
47. 47 Burkhard PR, Vingerhoets FJG, Alberque C, Landis T. Olanzapine-induced neuroleptic malignant syndrome. Arch Gen Psychiatry 1999; 56:101-102. This is a case report involving one patient.
48. 48 Wirshing DA, Marshall BD, Green MF, Mintz J, Marder SR, Wirshing WC. Risperidone in treatment-refractory schizophrenia. Am J Psychiatry 1999; 156:1374-1379. This prospective study involved 67 patients.
49. 49 Allison DB, Mentore JL, Heo M, Chandler L, Cappelleri JC, Infante M, Weiden P, et al. Meta-anatysis of the effects of anti-psychotic medications on weight gain. Am J Psychiatry 1999 (in press, to be published November 1999).