IOIBD questionnaire on the clinical use of azathioprine, 6-mercaptopurine, cyclosporin A and methotrexate in the treatment of inflammatory bowel diseases

European Journal of Gastroenterology and Hepatology

Volumn 12, Issue 1, 2000, Pages 13-18

  Meuwissen, Stephan G M ^a,c   Ewe, Klaus ^a   Gassull, Miquel A ^a   Geboes, Karel ^a   Jewell, Derek ^a   Pallone, Francesco ^a   Rachmilewitz, Dan ^a   Rask Madsen, Jorgen ^a   Riddell, Bob H ^a   Sandborn, Bill J ^a   Schmuck, Mary Lou ^b  

^a Intl Org for the Stud of I   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

6 mercaptopurine; Azathioprine; Crohn's disease; Cyclosporin A; Immunosuppression; Inflammatory bowel disease; International; Methotrexate; Pancreatitis; Pregnancy; Questionnaire; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; MERCAPTOPURINE; METHOTREXATE; STEROID;

ACUTE PANCREATITIS; ARTICLE; COLON CANCER; ENTERITIS; EUROPE; EXPERIENCE; GENERAL HOSPITAL; HUMAN; KIDNEY CARCINOMA; LEUKEMIA; LYMPHOMA; MEDICAL PRACTICE; NORMAL HUMAN; NORTH AMERICA; PREGNANCY; PRESCRIPTION; PRIORITY JOURNAL; QUESTIONNAIRE; SIDE EFFECT; ULCERATIVE COLITIS; UNIVERSITY HOSPITAL;

EID: 0033973974     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200012010-00004     Document Type: Article

References (37)

1. 1 O'Brien JJ, Bayless TM, Bayless JA. Use of azathioprine or 6-mercaptopurine in the treatment of Crohn's disease. Gastroenterology 1991 ; 101:39-46.
2. 2 Sandborn WJ, Tremaine WJ, Schroeder KW, Steiner BL, Batts KP, Lawson GM. Cyclosporine enemas for treatment-resistant, mildly to moderately active, left-sided ulcerative colitis [see comments]. Am J Gastroenterol 1993; 88:640-645.
3. 3 Connell WR, Kamm MA, Dickson M, Balkwill M, Ritchie JK, Lennard-Jones JE. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet 1994; 343:1249-1252.
4. 4 Connell WR, Kamm MA, Ritchie JK, Lennard-Jones JE. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease. Gut 1994; 34:1081-1085.
5. 5 Sandborn WJ, Tremaine WJ, Schroeder KW. A placebo-controlled trial of cyclosporine enemas for mildly to moderately active left-sided ulcerative colitis. Gastroenterology 1994; 106:1429-1435.
6. 6 Jewell DP, Lennard-Jones JE, Lowes J, Dalton HR, Shaffer JL, Littlewood A, et al. Oral cyclosporin for chronic active Crohn's disease: a multicentre controlled trial. Eur J Gastroenterol Hepatol 1994; 6:499-505.
7. 7 Lichtiger S, Present DH, Kornbluth A, Gelernt I, Bauer J, Galler G, et al. Cyclosporine in severe ulcerative colitis refractory to steroid therapy [see comments]. N Engl J Med 1994; 330:1841-1845.
8. 8 Sandborn WJ, Van OE, Zins BJ, Tremaine WJ, Mays DC, Lipsky JJ. An intravenous loading dose of azathioprine decreases the time to response in patients with Crohn's disease. Gastroenterology 1995; 109:1808-1817.
9. 9 Sandborn WJ. A critical review of cyclosporine therapy in inflammatory bowel disease. Inflamm Bowel Dis 1995; 1:48-63.
10. 10 Feagan BG, Rochon J, Fedorak RN, Irvine EJ, Wild G, Sutherland L, et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med 1995; 332:292-297.
11. 11 Pearson DC, May GR, Fick GH, Sutherland LR. Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysia. Ann Intern Med 1995; 123:132-142.
12. 12 Van Os EC, Zins BJ, Sandborn WJ, Mays DC, Tremaine WJ, Mahoney DW, et al. Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration. Gut 1996; 39:63-68.
13. 13 Bouhnik Y, Lemann M, Mary J-Y, Scemana G, Taï R, Matuchanski C, et al. Long-term follow up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. Lancet 1996; 347:215-219.
14. 14 Sandborn WJ. A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate. Am J Gastroenterol 1996; 91:423-433.
15. 15 Markowitz J, Grancher K, Mandel F, Daum F. Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Am J Gastroenterol 1993; 88:44-48.
16. 16 Kozarek R, Bedard C, Patterson D, Justus P, Sandford R, Greene M, et al. Cyclosporin use in the precolectomy chronic ulcerative colitis patient: a community experience and its relationship to prospective and controlled clinical trials. Pacific Northwest Gastroenterology Society [see comments]. Am J Gastroenterol 1995; 90:2093-2096.
17. 17 Present DH, Meltzer SJ, Krumholz MP, Wolke A, Korelitz BI. 6-Mercaptopurine in the management of inflammatory bowel disease: short-term and long-term toxicity. Ann Intern Med 1989; 3:641-649.
18. 18 Korelitz BI. Immunosuppressives. In: Therapy of Inflammatory Bowel Disease. Peppercorn MA (Editor). New York: Marcel Dekker; 1990. pp. 103-133.
19. 19 Markowitz J, Rosa J, Grancher K, Aiges H, Daum F. Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease [see comments]. Gastroenterology 1990; 99:1347-1351.
20. 20 Korelitz BI, Adler DJ, Mendelsohn RA, Sacknoff AL. Long-term experience with 6-mercaptopurine in the treatment of Crohn's disease. Am J Gastroenterol 1993; 88:1198-1205.
21. 21 Rhodes J, Bainton D, Beck P, Campbell H. Controlled trial of azathioprine in Crohn's disease. Lancet 1971 ; 11:1273-1276.
22. 22 Alstead EM, Ritchie JK, Lennard-Jones JE, Farthing MJG, Clark ML. Safety of azathioprine in inflammatory bowel disease. Gastroenterology 1990; 99:443-446.
23. 23 Ewe K, Press AG, Singe CC, Stufler M, Ueberschaer B, Hommel G, et al. Azathioprine combined with prednisolone or monotherapy with prednisolone in active Crohn's disease. Gastroenterology 1993; 105:367-372.
24. 24 Lemann N, Bouhnik Y, Kmieciak-Le Corguille M, Bonnet J, Coffin B, Marteau P, et al. Treatment of Crohn's disease with mercaptopurine in patients intolerant to azathioprine [Abstract]. Gastroenterology 1997; 112(suppl 4):A1012.
25. 25 Hawthorne AB, Logan RF, Hawkey CJ, Foster PN, Axon AT, Swarbrick ET, et al. Randomised controlled trial of azathioprine withdrawal in ulcerative colitis. BMJ 1992; 305:20-22.
26. 26 Fernández-Banares F, Bertrán X, Esteve-Comas M, Cabré E, Menacho M, Humbert P, et al. Azathioprine is useful in maintaining long-term remission induced by intravenous cyclosporine in steroid-refractory severe ulcerative colitis. Am J Gastroenterol 1996; 91:2498-2499.
27. 27 Munkholm P, Langholz E, Davidsen M, Binder V. Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut 1994; 35:360-362.
28. 28 Colonna T, Korelitz BI. The role of leukopenia in the 6-mercaptopurine-induced remission of refractory Crohn's disease. Am J Gastroenterol 1994; 89:362-366.
29. 29 Satsangi J, Marshall J, Roskell D, Jewell D. Ulcerative colitis complicated by renal cell carcinoma: a series of three patients. Gut 1996; 38:148-150.
30. 30 Forbes A, Reading NG. Review article: the risks of malignancy from either immunosuppression or diagnostic radiation in inflammatory bowel disease. Aliment Pharmacol Ther 1995; 9:465-470.
31. 31 Farrell R, Kileen P, Mahmud N, O'Brien DS, Kelleher D, Keeling PWN, et al. increased risk of non-Hodgkin's lymphoma with immunomodulatory therapy of inflammatory bowel disease [Abstract]. Gastroenterology 1997; 112(suppl 4):A969.
32. 32 O'Neill J, Pathmakanthan J, Goh J, Costello S, MacMathuna P, O'Connell R, et al. Cyclosporine A induces remission in fistulous Crohn's disease but relapse occurs upon cessation of treatment [Abstract]. Gastroenterology 1997; 112(suppl 4):A1056.
33. 33 Egan L, Sandborn W, Tremaine WJ. Outcome of intravenous followed by oral cyclosporine (CYA) for refractory Crohn's disease [Abstract]. Gastroenterology 1997; 112(suppl 4):A964.
34. 34 Carbonnel F, Boruchowicz A, Duclos B, Soulé C, Lerebours E, Lémann M, et al. Intravenous cyclosporine in attacks of ulcerative colitis. Dig Dis Sci 1996; 41:2471-2476.
35. 35 Hyde G, Thillainayagam A, Jewell D. Intravenous cyclosporin as rescue therapy in severe ulcerative colitis? [Abstract]. Gastroenterology 1997; 112(suppl 4):A1002.
36. 36 Egan LJ, Sandborn WJ. Methotrexate for inflammatory bowel disease: pharmacology and preliminary results. Mayo Clin Proc 1996; 71:69-80.
37. 37 Stack WA, Williams D, Stevenson M, Logan RFA. Immunosuppressive therapy for ulcerative colitis: results of a nationwide survey among consultant physician members of the Bristish Society of Gastroenterology. Alim Pharm Ther 1999; 13:569-575.