Long-term depression in the hippocampus in vivo is associated with protein phosphatase-dependent alterations in extracellular signal-regulated kinase

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 192-198

  Norman, Eric D ^a   Thiels, Edda ^a   Barrionuevo, German ^a   Klann, Eric ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Extracellular signal regulated kinase; Hippocampus; Long term depression; Plasticity; Protein phosphatase 1; Protein phosphatase 2A

Indexed keywords

CYANOGINOSIN; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; HIPPOCAMPUS; IMMUNOREACTIVITY; LONG TERM POTENTIATION; NERVE CELL INHIBITION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOTTING, WESTERN; ENZYME INHIBITORS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICROCYSTINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; OKADAIC ACID; PEPTIDES, CYCLIC; PHOSPHOPROTEIN PHOSPHATASE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0033970435     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740192.x     Document Type: Article

References (31)

1. Ahn N. G., Seger R., Bratlien R. L., Diltz, C. D., Tonks N. K., and Krebs E. G. (1991) Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J. Biol. Chem. 266, 4220-4227.
2. Anderson N. G., Maller J. L., Tonks N. K., and Sturgill T. W. (1990) Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343, 651-653.
3. Atkins C. M., Selcher J. C., Petraitis J. J., Trzaskos J. M., and Sweatt J. D. (1998) The MAPK cascade is required for mammalian associative learning. Nat. Neurosci. 1, 602-609.
4. Bliss T. V. P. and Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
5. Blitzer R. D., Conner J. H., Brown G. P., Wong T., Shenolikar S., Iyengar R., and Landau E. M. (1998) Gating of CAMKII by cAMP-regulated protein phosphatase activity during LTP. Science 280, 1940-1943.
6. Blum S., Moore A., Adams F., and Dash P. (1999) A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory. J. Neurosci. 19, 3535-3544.
7. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
8. Chen C. and Tonegawa S. (1997) Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain. Annu. Rev. Neurosci. 20, 157-184.
9. Chernoff J., Li H. C., Cheng Y. S., and Chen L. B. (1983) Characterization of a phosphotyrosyl protein phosphatase activity associated with a phosphoseryl protein phosphatase of Mr = 95,000 from bovine heart. J. Biol. Chem. 258, 7852-7857.
10. Cohen P., Holmes C. F. B., and Tsukitani Y. (1990) Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem. Sci. 15, 98-102.
11. Coussens C. M. and Abraham W. C. (1997) Tyrosine phosphatase inhibitors block LTP and LTD in area CA1 of the hippocampus. Soc. Neurosci. Abstr. 23, 1175.
12. Damuni Z., Xiong H., and Li M. (1994) Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A. FEBS Lett. 352, 311-314.
13. English J. D. and Sweatt J. D. (1996) Activation of p42 mitogen-activated protein kinase in hippocampal long-term potentiation. J. Biol. Chem. 271, 24329-24332.
14. English J. D. and Sweatt J. D. (1997) A requirement for the mitogen-activated protein kinase cascade in hippocampal long-term potentiation. J. Biol. Chem. 272, 19103-19106.
15. Hebb D. (1949) The Organization of Behavior. Wiley, New York.
16. Honkanen R. E., Zwiller J., Moore R. E., Daily S. L., Khatra B. S., Dukelow M., and Boynton A. L. (1990) Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J. Biol. Chem. 265, 19401 -19404.
17. Hrabetova S. and Sacktor T. C. (1996) Bidirectional regulation of protein kinase M zeta in the maintenance of long-term potentiation and long-term depression. J. Neurosci. 16, 5324-5333.
18. Kameyama K., Lee H. K., Bear M. F.. and Huganir R. L. (1998) Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron 21, 1163-1175.
19. Kandel E. R. and Schwartz J. H. ( 1982) Molecular biology of learning: modulation of transmitter release. Science 218, 433-443.
20. Kanterewicz B. I., Knapp L. T., and Klann E. (1998) Stimulation of p42 and p44 mitogen-activated protein kinases by reactive oxygen species and nitric oxide in hippocampus. J. Neurochem. 70, 1009-1016.
21. Keranen L. M., Dutil E. M., and Newton A. C. (1995) Protein kinase C is regulated in vivo by three functionally distinct phosphorylations. Curr. Biol. 5, 1394-1403.
22. Klann E., Chen S. J., and Sweatt J. D. (1993) Mechanism of protein kinase C activation during the induction and maintenance of long-term potentiation probed using a selective peptide substrate. Proc. Natl. Acad. Sci. USA 90, 8337-8341.
23. Lynch G. and Baudry M. (1984) The biochemistry of memory: a new and specific hypothesis. Science 224, 1057-1063.
24. Mulkey R. M., Herron C. E., and Malenka R. C. (1993) An essential role for protein phosphatases in hippocampal long-term depression. Science 261, 1051-1055.
25. Mulkey R. M., Endo S., Shenolikar S., and Malenka R. C. (1994) Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature 369, 486-488.
26. Roberson E. D., English J. D., and Sweatt J. D. (1996) A biochemist's view of long-term potentiation. Learn. Mem. 3, 1-24.
27. Seger R., Ahn N. G., Boulton T. G., Yancopoulos G. D., Panayotatos N., Radziejewska E., Ericsson L., Bratlien R. L., Cobb M. H., and Krebs E. G. (1991) Microtubule-associated protein 2 kinases, ERKI and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. Proc. Natl. Acad. Sci. USA 88, 6142-6146.
28. 2+-induced persistent protein kinase C activation in rat hippocampal homogenates. Second Messengers Phosphoproteins 14, 109-126.
29. Thiels E., Barrionuevo G., and Berger T. W. (1994) Excitatory stimulation during postsynaptic inhibition induces long-term depression in hippocampus in vivo. J. Neurophysiol. 72, 3009-3016.
30. Thiels E., Norman E. D., Barrionuevo G., and Klann E. (1998) Transient and persistent increases in protein phosphatase activity during long-term depression in the adult hippocampus in vivo. Neuroscience 86, 1023-1029.
31. Wu J., Rossomando A. J., Her J. H., Del Vecchio R., Weber M. J., and Sturgill T. W. (1991) Autophosphorylation in vitro of recombinant 42-kilodalton mitogen-activated protein kinase on tyrosine. Proc. Natl. Acad. Sci. USA 88, 9508-9512.