Phosphono analogs of glutathione: Inhibition of glutathione transferases, metabolic stability, and uptake by cancer cells

Biochemical Pharmacology

Volumn 59, Issue 8, 2000, Pages 973-981

  Kunze, Thomas ^a   Heps, Stefan ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Drug uptake; Glutathione analog; Glutathione transferase inhibitor; Kinetic studies; Neoplasm drug resistance; Phosphonic acid

Indexed keywords

GLUTATHIONE DERIVATIVE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CONTROLLED STUDY; DRUG PENETRATION; DRUG STABILITY; DRUG UPTAKE; ENZYME INHIBITOR INTERACTION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; DRUG STABILITY; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HT29 CELLS; HUMANS; ISOENZYMES; NEOPLASMS; PHOSPHONIC ACIDS; SWINE; TUMOR CELLS, CULTURED;

EID: 0033969838     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00401-3     Document Type: Article

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