Comparison of the frequency of behavioral disinhibition on alprazolam, clonazepam, or no benzodiazepine in hospitalized psychiatric patients

Journal of Clinical Psychopharmacology

Volumn 20, Issue 1, 2000, Pages 7-11

  Rothschild, Anthony J ^a,b,c   Shindul Rothschild, Judith A ^d   Viguera, Adele ^c,e   Murray, Margaret ^f   Brewster, Suzanne ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MCLEAN HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BOSTON COLLEGE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; CLONAZEPAM;

ADULT; AGED; ANGER; ANXIETY NEUROSIS; ARTICLE; ASSAULT; AUTOMUTILATION; BEHAVIOR DISORDER; BEHAVIORAL DISINHIBITION; BORDERLINE STATE; DEPRESSION; DOSE RESPONSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; MENTAL DISEASE; OBSESSION; PANIC; PERSONALITY DISORDER; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SCHIZOIDISM; SCHIZOPHRENIA; SUICIDE; VIOLENCE;

ADOLESCENT; ADULT; AGED; ALPRAZOLAM; ANALYSIS OF VARIANCE; ANTI-ANXIETY AGENTS; BEHAVIORAL SYMPTOMS; CLONAZEPAM; FEMALE; HOSPITALIZATION; HUMANS; MALE; MENTAL DISORDERS; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 0033969541     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-200002000-00003     Document Type: Article

References (29)

1. Balter MB. Clinical epidemiology of treatment with prescription medications with dependent liability. From the Faculty Presentation at Montebello Conference on Development of Educational Strategies for Prescribing Drugs with Dependence Liability: Optimal Therapy the Goal. Montebello, Quebec, Canada, June 2-3, 1988.
2. Nelson RC. Drug safety, pharmacoepidemiology, and regulatory decision making. In: Harzema AG, Prota MS, Tilson HH, eds. Pharmacoepidemiology: an introduction. Cincinnati: Harvey Whitney Books, 1991.
3. IMS National Disease Therapeutic Index. Plymouth Meeting, PA: IMS America, 1992.
4. Rosenbaum JF, Woods SW, Groves JE, Klerman GL. Emergence of hostility during alprazolam treatment. Am J Psychiatry 1984; 141:792-3.
5. Gardner DL, Cowdry RW. Alprazolam-induced dyscontrol in borderline personality disorder. Am J Psychiatry 1985;142:98-100.
6. Byrd JC. Alprazolam-associated rage reaction. J Clin Psychopharmacol 1985;5:186-8.
7. French AP. Dangerously aggressive behavior as a side effect of alprazolam [letter]. Am J Psychiatry 1989;146:276.
8. Rapaport M, Braff DL. Alprazolam and hostility [letter]. Am J Psychiatry 1985;142:146.
9. Cole JO, Kando JC. Adverse behavioral events reported in patients taking alprazolam and other benzodiazepines. J Clin Psychiatry 1993;54[suppl]:49-61.
10. Jonas JM, Cohon MS. A comparison of the safety and efficacy of alprazolam versus other agents in the treatment of anxiety, panic, and depression: a review of the literature. J Clin Psychiatry 1993;54[suppl]:25-45.
11. Jonas JM, Hearron AE Jr. Alprazolam and suicidal ideation: a meta-analysis of controlled trials in the treatment of depression. J Clin Psychopharmacol 1996;16:208-11.
12. Rothschild AJ. Disinhibition, amnestic reactions, and other adverse reactions secondary to triazolam: a review of the literature. J Clin Psychiatry 1992;53[suppl]:69-79.
13. Dietch JT, Jennings RK. Aggressive dyscontrol in patients treated with benzodiazepines. J Clin Psychiatry 1988;:49:184-8.
14. Lion JR, Azearate CL, Koepke HH. "Paradoxical rage reactions" during psychotropic medication. Dis Nerv Syst 1975;36:557-8.
15. Zisook S, DeVaul RA. Adverse behavioral effects of benzodiazepines. J Fam Pract 1977;5:963-6.
16. Gardos G. Disinhibition of behavior by antianxiety drugs. Psychosomatics 1980;21:1025-6.
17. Ingram I, Timbury T. Side effects of Librium [letter]. Lancet 1960;279:766.
18. Murray N. Covert effects of chlordiazepoxide therapy. J Neuropsychiatry 1962;3:168-70.
19. Karch FE. Rage reaction associated with chlorazepate dipotassium. Ann Intern Med 1979;91:61-2.
20. Salzman C, Kochansky GE, Shader RI, Porrino LJ, Harmatz JS, Swett CP Jr. Chlordiazepoxide-induced hostility in a small group setting. Arch Gen Psychiatry 1974;31:401-5.
21. Kochansky GE, Salzman C, Shader RI, Harmatz JS, Ogeltree AM. The differential effects of chlordiazepoxide and oxazepam on hostility in a small group setting. Am J Psychiatry 1975;132:861-3.
22. Rickels K, Downing RW. Chlordiazepoxide and hostility in anxious outpatients. Am J Psychiatry 1974;131:442-4.
23. Merrill FB, Scott GE, Krebs R, Thompson BL, Ryan HF. Suicidal thoughts and tendencies association with diazepam therapy. JAMA 1968;203:1137-9.
24. Hall RCW, Jaffe JR. Aberrant response to diazepam: a new syndrome. Am J Psychiatry 1972;129:114-8.
25. George A, Nathan RS, Schulz PM, Perel JM, Soloff PH. Behavioral dyscontrol in borderline patients treated with amitriptyline. Psychopharmacol Bull 1987;23:177-81.
26. Faltus FJ. The positive effect of alprazolam in the treatment of three patients with borderline personality disorder. Am J Psychiatry 1984;141:802-3.
27. Edwards JG, Inman WHW, Pearce GL, Rawson NSB. Prescription event monitoring of 10,895 patients treated with alprazolam. Br J Psychiatry 1991;58:387-92.
28. Boyd JH, Weissman MM. Epidemiology. In: Paykel ES, ed. Handbook of affective disorders. Edinburgh: Churchill-Livingstone, 1982;109-25.
29. Balter MB, Manheimer DI, Mellinger GD, Uhlenhuth EH. A cross-national comparison of anti-anxiety sedative drug use. Curr Med Res Opin 1984;8[suppl 4]:5-20.