Provocative use testing of methyldibromo glutaronitrile in a cosmetic shampoo

Contact Dermatitis

Volumn 42, Issue 2, 2000, Pages 64-67

  Tosti, Antonella ^a,b   Vincenzi, Colombina ^a   Smith, Karin A ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Allergic contact dermatitis; Contact allergy; Cosmetics; Diagnostic patch test; Dibromodicyanobutane; Euxyl K400; Methyldibromo glutaronitrile; Preservative; Provocative use test; Rinse off products; Shampoo; Tektamer 38

Indexed keywords

COSMETIC; EUXYL K 400; PRESERVATIVE; SHAMPOO;

ADOLESCENT; ADULT; ARTICLE; CONTACT DERMATITIS; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PROVOCATION TEST;

ADOLESCENT; ADULT; AGED; ALLERGENS; COSMETICS; DERMATITIS, ALLERGIC CONTACT; FEMALE; FOLLOW-UP STUDIES; HAIR PREPARATIONS; HUMANS; IMMUNIZATION; MALE; MIDDLE AGED; NITRILES; PRESERVATIVES, PHARMACEUTICAL; SAFETY; SKIN TESTS;

EID: 0033968914     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0536.2000.042002064.x     Document Type: Article

References (11)

1. 1. Tosti A, Vincenzi C, Trevisi P, Guerra L. Euxyl K400: incidence of sensitization, patch test concentration and vehicle. Contact Dermatitis 1995: 33: 193 195.
2. 2. Bruze M, Gruvberger B, Agrup G. Sensitization studies in the guinea pig with the active ingredients of Euxyl K400. Contact Dermatitis 1988: 18: 37-39.
3. 3. Hausen B M. The sensitizing potency of Euxyl K400 and its components 1, 2 dibromo-2, 4 dicyanobutane and 2-phenoxyethanol. Contact Dermatitis 1993: 28: 149-153.
4. 4. De Groot A C, Van Ginkel C J W, Weijland J W. Methyldibromoglutaronitrile (Euxyl K400): an important "new" allergen in cosmetics. J Am Acad Dermatol 1996: 35: 743-747.
5. 5. Marks J G, Belsito D V, DeLeo V A, Fowler J F, Fransway A F, Maibach H I, Mathias C G T, Nethercott J R, Rietschel R L, Sherertz E F, Storrs F J, Taylor J S. North American Contact Dermatitis Group patch test results for the detection of delayed-type hypersensitivity to topical allergens. J Am Acad Dermatol 1998: 38: 911-918.
6. 6. Jackson J M, Fowler J F. Methyldibromoglutaronitrile (Euxyl K400): A new and important sensitizer in the United States? J Am Acad Dermatol 1998: 38: 934-937.
7. 7. Fernandez E, Navarro J A, del Pozo L, Fernandez de Corrès L. Allergic contact dermatitis due to dibromodicyanobutane in cosmetics. Contact Dermatitis 1995: 32: 109-110.
8. 8. Van der Walle H B, Brunsveld V M. Dermatitis in hair-dressers (1): the experience of the past 4 years. Contact Dermatitis 1994: 30: 217-221.
9. 9. Fewings J, Menné T. An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/ MI) with focus on rinse-off products. Contact Dermatitis 1999: 41; 1-13
10. 10. The Procter & Gamble Company. Personal communication, 1999.
11. 11. The Procter & Gamble Company. Personal communication, 1999.