Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin

Gene

Volumn 242, Issue 1-2, 2000, Pages 59-64

  Meng, Gaoyuan ^a   Inazawa, Johji ^b   Ishida, Reiko ^a   Tokura, Katsunobu ^a   Nakahara, Kazuhiko ^c   Aoki, Katsunori ^a,c   Kasai, Masataka ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b THE UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

1q44 ter; POZ domain; Transcriptional repressor

Indexed keywords

ZINC FINGER PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME 1Q; CHROMOSOME MAP; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ISOLATION; GENE STRUCTURE; GENETIC ORGANIZATION; HETEROCHROMATIN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CLONING, MOLECULAR; DNA; DNA, COMPLEMENTARY; EXONS; GENE EXPRESSION; GENES; HETEROCHROMATIN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MALE; MICE; MOLECULAR SEQUENCE DATA; REPRESSOR PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0033967954     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00477-1     Document Type: Article

References (18)

1. Albagli O., Dhordain P., Deweindt C., Lecocg G., Leprince D. The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins. Cell Growth Differ. 6:1995;1193-1198.
2. Aoki K., Inazawa J., Takahashi T., Kasai M. Genomic structure and chromosomal localization of the gene encoding Translin, a recombination hotspot binding protein. Genomics. 43:1997;237-241.
3. Aoki K., Meng G., Suzuki K., Takashi T., Kameoka Y., Nakahara K., Ishida R., Kasai M. RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression. J. Biol. Chem. 273:1998;26698-26704.
4. Bardwell V.J., Treisman R. The POZ domain: a conserved protein-protein interaction motif. Genes Dev. 8:1994;1664-1677.
5. Becker K.G., Lee I.J., Nagle J.W., Canning R.D., Gado A.M., Torres R., Polymeropoulos M.H., Massa P.T., Biddison W.E., Drew P.D. C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain. Int. J. Dev. Neurosci. 15:1997;891-899.
6. Breathnach R., Chambon P. Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:1981;349-383.
7. Halal F., Vekemans M., Kaplan P., Zeesman S. Distal deletion of chromosome 1q in an adult. Am. J. Med. Genet. 35:1990;379-382.
8. Hu Z.Z., Zhuang L., Meng J., Dufau M.L. Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1. J. Biol. Chem. 273:1998;26225-26235.
9. Inazawa J., Fukunaga R., Seto Y., Nakagawa H., Misawa S., Abe T., Nagata S. Assignment of the human granulocyte colony-stimulating factor receptor gene (CSF3R) to chromosome 1 at p35-p34.3. Genomics. 10:1991;1075-1078.
10. Jiang J.G., Zarnegar R. A novel transcriptional regulatory region within the core promoter of the hepatocyte growth factor gene is responsible for its inducibility by cytokines via the C/EBP family of transcription factors. Mol. Cell. Biol. 17:1997;5758-5770.
11. Kaplan J., Calame K. The ZiN/POZ domain of ZF5 is required for both transcriptional activation and repression. Nucleic Acids Res. 25:1997;1108-1116.
12. Kennerknecht I., Barbi G., Rodens K. Dup(1q)(q42→qter) syndrome: case report and review of literature. Am. J. Med. Genet. 47:1993;1157-1160.
13. Murayama K., Greenwood R.S., Rao K.W., Aylsworth A.S. Neurological aspects of del(1q) syndrome. Am. J. Med. Genet. 40:1991;488-492.
14. Numoto M., Niwa O., Kaplan J., Wong K.-K., Merrell K., Kamiya K., Yanagihara K., Calame K. Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins. Nucleic Acids Res. 21:1993;3767-3775.
15. Raynaud S.D., Brunet B., Chischportich M., Bayle J., Gratecos N., Pesce A., Dujardin P., Flandrin G., Ayraud N. Recurrent cytogenetic abnormalities observed in complete remission of acute myeloid leukemia do not necessarily mark preleukemic cells. Leukemia. 8:1994;245-249.
16. Sugawara M., Scholl T., Ponath P.D., Strominger J.L. A factor that regulates the class II major histocompatibility complex gene DPA is a member of a subfamily of zinc finger proteins that includes a Drosophila developmental control protein. Mol. Cell. Biol. 14:1994;8438-8450.
17. Wilmore H.P., White G.F., Howell R.T., Brown K.W. Germline and somatic abnormalities of chromosome 7 in Wilms' tumor. Cancer Genet. Cytogenet. 77:1994;93-98.
18. Zollman S., Godt D., Prive G.G., Couderc J.L., Laski F.A. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc. Natl. Acad. Sci. USA. 91:1994;10717-10721.