ABT-627, an endothelin ET(A) receptor-selective antagonist, attenuates tactile allodynia in a diabetic rat model of neuropathic pain

European Journal of Pharmacology

Volumn 388, Issue 1, 2000, Pages 29-35

  Jarvis, Michael F ^a   Wessale, Jerry L ^a   Zhu, Chang Z ^a   Lynch III, James J ^a   Dayton, Brian D ^a   Calzadilla, Samuel V ^a   Padley, Robert J ^a   Opgenorth, Terry J ^a   Kowaluk, Elizabeth A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Allodynia; Diabetic neuropathy; Endothelin; Streptozotocin

Indexed keywords

(2ALPHA,3BETA,4ALPHA) 4 (1,3 BENZODIOXOL 5 YL) 1 [2 (2,6 DIETHYLPHENYL)AMINO] 2 OXOETHYL] 2 (4 PROPOXYPHENYL) 3 PYRROLIDINECARBOXYLIC ACID; ATRASENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; MORPHINE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; MALE; NEURALGIA; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANALGESICS, NON-NARCOTIC; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; HUMANS; MALE; PAIN; PAIN MEASUREMENT; PHYSICAL STIMULATION; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; STEREOISOMERISM; VASOCONSTRICTOR AGENTS;

EID: 0033967648     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00865-1     Document Type: Article

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