Comparison of the permeability surface product (PS) of the blood capillary wall in skeletal muscle tissue of various species and in vitro porous membranes using hydrophilic drugs

Journal of Pharmaceutical Sciences

Volumn 89, Issue 1, 2000, Pages 115-127

  Schmittmann, Georg ^a   Rohr, Uwe D ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Blood capillary wall; In vitro in viva correlation; Intramuscular application; Membrane surface; Permeability; PS product; Unstirred water layer

Indexed keywords

DRUG;

ARTICLE; BLOOD VESSEL PERMEABILITY; DRUG DIFFUSION; DRUG ELIMINATION; DRUG TRANSPORT; HUMAN; HYDROPHOBICITY; NONHUMAN;

EID: 0033966130     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6017(200001)89:1<115::AID-JPS12>3.0.CO;2-7     Document Type: Article

References (40)

1. Higuchi WI. 1992. Bioavailability and bioequivelance of topically delivered drugs. Abstracts of FDA workshop on topical drug delivery, Arlington, VA.
2. Shah VP. 1992. Drug release standards. FDA workshop on topical drug delivery, Arlington, VA.
3. Beck-Sickinger A, Marrer S, Imanidis G. 1996. Quality assurance in the development, production control, and registration of peptides and proteins. Pharm Acta Helv 71:381.
4. Bassingthwaigthe JB. 1974. Blood flow and diffusion through mammalian organs. Science 167: 1347-1353.
5. Bass L, Robinson P. 1982. Capillary permeability of heterogeneous organs. A parsimonious interpretation of indicator diffusion data. Clin Exp Pharmacol Physiol 9:363-388.
6. Crone C, Levitt DG. 1984. Capillary permeability to small solutes. In: Renkin EM, Michel CC, editors. Handbook of physiology; American Physiological Society. Bethesda, MD, Vol 4, p 411-491.
7. Haunso S, Paaske WP, Sejrsen P, Amtrop O. 1980. Capillary permeability in canine myocardium as determined by bolus injection. Acta Physiol Scand 108:389-397.
8. Haraldson B. 1988. Diffusional transport of albumin from interstitium to blood across small pores in the capillary walls of rat skeletal muscle. Acta Physiol Scand 133:63-71.
9. 131I-albumin in the resting human. Cardiovasc Res 24:737-740.
10. Rippe B, Haraldson B. 1986. Capillary permeability in rat hindquarters as determined by estimation of capillary reflection coefficients. Acta Physiol Scand 127:289-303.
11. Wolf MB. 1994. Identification of microvascular transport pathways in skeletal muscle. Am J Physiol 267:H383-H399.
12. Watson PD. 1995. Permeabilities of skeletal muscle capillaries to small solutes. Am J Physiol 268:184-193.
13. Caldwell JH, Martin GV, Raymond GM, Bassingthwaighte JB. 1994. Regional myocardial flow and capillary permeability-surface area product are nearly proportional. Am J Physiol 267:654-666.
14. Overholser KA, Bhatte MJ, Laughlin MH. 1991. Modeling the effect of flow heterogeneity on coronary permeability-surface area. J Appl Physiol 71:758-769.
15. 51Cr EDTA in the excised forearm of long-term diabetics. Clin Sci Mol Med 39:39-49.
16. m DTPA in the human forearm. Phys Med Biol 37:1759-1771.
17. 51Cr]EDTA in human forearm. Acta Physiol Scand 133:335-342.
18. Shibata M, Yoshida M, Kamiya A. 1991. Measurement of local capillary permeability in skeletal muscle by microscopic clearance method. Jpn J Physiol 41:725-734.
19. Deguchi Y, Terasaki T, Kawasaki S, Tsuji A. 1991. Muscle microdialysis as a model to relate the drug concentration in tissue interstitial fluid and dialysate. J Pharmacobiodyn 14:483-492.
20. Sejrsen P. 1979. Capillary permeability measured by bolus injection, residue and venous detection. Acta Physiol Scand 105:73-92.
21. Paaske WP. 1976. Capillary permeability in cutaneous tissue. Acta Physiol Scand 98:492-499.
22. Rohr UD, Schmittmann G, Kissel T. 1997. In vitro model for intramuscular drug bioavailability. II Proc Int Symp Control Rel Bioact Mater 24:533-534.
23. Higuchi WI. 1961. Drug relese out of ointments. J Pharm Sci 33:237-241.
24. Roseman T, Higuchi WI. 1970. Drug release out of a matrix across an adjacent membrane. J Pharm Sci 59:353-357.
25. Renkin EM. 1955. Effect of blood flow on diffusion kinetics in isolated perfused hindlegs of cats: a double circulation hypothesis. Am J Physiol 183: 125-136.
26. Renkin EM. 1959. Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles. Am J Physiol 197:1205-1210.
27. Beck RE, Schultz JS. 1972. Hindrance of solute diffusion within membranes as measured with microporous membranes of known pore geometry. Biochim Biophys Acta 255:273-303.
28. Aguir A. 1979. Gastrointestinal absorption of drugs. American Pharmaceutical Association, Washington D.C.
29. Baker RW, Lonsdale HK. 1973. Controlled release: Mechanism and rates. In Tanquary AC, Lacey RE, editor. Controlled release of biological active agents. Plenum Press: New York.
30. Meylan WM, Howard PH. 1995. Atom/fragment contribution method for estimating octanol-water partition coefficients. J Pharm Sci 84:83-92.
31. Harrison DJ, Knutson K. 1995. Accurate determination of skin flux from flowthrough cell diffusion data. Pharm Res 12:2003-2011.
32. Abdou H. 1989. Dissolution, Bioavailability and Bioequivalence. Mack Publishing Company: Easton, PA.
33. Hanson W. 1977. Solving the puzzle of random variables in dissolution techniques. Pharm Technol 32:321-348.
34. Langenbucher F. 1969. In vitro assessment of dissolution kinetics: description and evaluation of a column type method. J Pharm Sci 58:1265-1269.
35. Gibaldi M. 1984. Biopharmaceutics and Clinical Pharmacokinetics. Lea and Febiger: Philadelphia, PA.
36. Kissel Th., Demirdere A. 1987. Microspheres: A controlled release system for parenteral application. In: Müller BW, editor. Controlled drug delivery; APV, Wissenschaftliche Verlagsgesellschaft: Stuttgart.
37. Morgan DJ. 1996. Permeability of myocardial capillaries to hydrophilic drugs: the paracellular pathway. Clin Exp Pharmacol Physiol 23:975-979.
38. Granger DN, Granger JP, Brace RA, Parker RE, Taylor AE. 1981. Analysis of the permeability of cat intestinal capillaries. Circ Res 44:335-344.
39. Rizzo A. 1990. Intramuscular injection of theophylline. J Asthma 27:165-169.
40. Azzam Z, Krivoy N, Alroy G, Zinder O. 1994. Serum kinase levels after a single intramuscular injection: dependence on injection volume. Ann Clin Biochem 31:193-194.