Influence of a 5HT1 receptor agonist on gastric accommodation and initial transpyloric flow in healthy subjects

Neurogastroenterology and Motility

Volumn 12, Issue 1, 2000, Pages 95-101

  Vingerhagen, S ^a   Hausken, Trygve ^a   Gilja, O H ^a   Berstad, A ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

Gastric accommodation; Sumatriptan; Transpyloric flow; Ultrasonography

Indexed keywords

SEROTONIN; SEROTONIN AGONIST; SEROTONIN RECEPTOR; SUMATRIPTAN; SUMATRIPTAN SUCCINATE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DYSPEPSIA; ECHOGRAPHY; EXHAUSTION; FATIGUE; FEMALE; FLUSHING; HUMAN; HUMAN EXPERIMENT; INGESTION; MALE; MEAL; MOTOR ACTIVITY; MUSCLE STIFFNESS; NAUSEA; NORMAL HUMAN; PAIN; PERISTALSIS; POSTPRANDIAL STATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH EMPTYING; STOMACH FUNDUS; THORAX PAIN; VERTIGO;

ADULT; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DYSPEPSIA; FEMALE; GASTRIC EMPTYING; HUMANS; MALE; PERISTALSIS; PYLORIC ANTRUM; REFERENCE VALUES; SEROTONIN AGONISTS; SUMATRIPTAN;

EID: 0033965956     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.2000.00184.x     Document Type: Article

References (21)

1. 1 Read NW, Houghten LA. Physiology of gastric emptying and pathophysiology of gastroparesis. Gastroenterol Clinics North Am 1989; 18: 359-73.
2. 2 Mawe GM, Schemann M, Wood JD, Gershon MD. Immunocytochemical analysis of potential neurotransmitters present in the myenteric plexus and muscular layers of the corpus of the guinea-pig stomach. The Anat Record 1989; 224: 431-42.
3. 3 Coulie B, Tack J, Maes B, Geypens B, De Roo M, Janssens J. Sumatriptan, a selective 5-HT1 receptor agonist, induces a lag phase for gastric emptying of liquids in humans. Am J Physiol 1997; 272: G902-8.
4. 4 Tack J, Coulie B, Wilmer A, Andrioli A, Janssens J. Effect of sumatriptan on gastric fundus tone and on the perception of gastric distension in man. Gastroenterology 1996; 110: A767.
5. 5 Tack J, Coulie B, Wilmer A, Peeters T, Janssens J. Actions of the 5-Hydroxytryptamine-1 receptor agonist sumatriptan on interdigestive gastrointestinal motility in man. Gut 1998; 42: 36-41.
6. 6 Hausken T, Berstad A. Wide antral area in patients with non-ulcer dyspepsia. Effect of cisapride. Scand J Gastroenterol 1992; 27: 427-32.
7. 7 Gilja OH, Hausken T, Ødegaard S, Berstad A. Monitoring postprandial size of the proximal stomach using ultrasonography. J Ultrasound 1995; 14: 81-9.
8. 8 King PM, Adam RD, Pryde A, McDicken WN, Heading RC. Relationships of human antroduodenal motility and transpyloric fluid movement: non-invasive observations with real-time ultrasound. Gut 1984; 25: 1384-91.
9. 9 King PM, Heading RC, Pryde A. Coordinated motor activity of the human gastroduodenal region. Dig Dis Sci 1985; 30: 219-24.
10. 10 Hausken T, Ødegaard S, Matre K, Berstad A. Antroduodenal motility and movements of luminal contents studied by duplex songraphy. Gastroenterology 1992; 102: 1583-90.
11. 11 Gilja OH, Hausken T, Wilhelmsen I, Berstad A. Impaired accommodation of proximal stomach to a meal in functional dyspepsia. Dig Dis Sci 1996; 41 (4): 689-96.
12. 12 Houghton LA, Fowler P, Keene ON, Read NW. Effect of sumatriptan, a new selective 5HT1-like agonist, on liquid emptying in man. Aliment Pharmacol Ther 1992; 6: 685-96.
13. 13 Hausken T, Gilja OH, Ødegaard S, Berstad A. Effects of glyceryl trinitrate on transpyloric flow of a soup meal. Scand J Gastroenterol 1998; 33: 484-90.
14. 14 Tack J, Coulie B, Janssens J. 5-HT1 receptor activation has a major impact on gastrointestinal functions in man. Gastroenterol 1996; 110 (Suppl. 4): A1123.
15. 15 Tack J, Piessevaux H, Coulie B, Caenepeel P, Janssens J. Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 1998; 115: 1346-52.
16. 16 Dechant KL, Clissold SP. Sumatriptan: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and clustered headache. Drugs 1992; 43: 776-98.
17. 17 Meulemans AL, Helsen LF, de Ridder WJA, Schuurkes JAJ. Effects of sumatriptan on the guinea-pig isolated stomach. Neurogastroenterol Motil 1996; 8: A183.
18. 18 Coulie B, Tack J, Sifrim D, Andrioli A, Janssens J. Role of nitric oxide in fasting gastric fundus tone and in 5HT1 receptor-mediated relaxation of gastric fundus. Am J Physiol 1999; 276: G373-7.
19. 19 Konturec JW, Thor P, Domschke W. Effects of nitric oxide on antral motility and gastric emptying in humans. Eur J Gastroenterol Hepatol 1995; 7: 97-102.
20. 20 Allescher HD, Daniel EE. Role of NO in pyloric, antral, and duodenal motility and its interaction with other inhibitory mediators. Dig Dis Sci 1994; 39: 73S-75S.
21. 21 Novitol R, Coffin B, Azpiroz F, Mearin F, Serra J, Malagelada JR. Gastric tone determines the sensitivity of the stomach to distension. Gastroenterology 1995; 108: 330-36.