The addition of topotecan to carboplatin and paclitaxel as first-line therapy for advanced ovarian cancer; Is it possible only with peripheral blood stem cell support?

European Journal of Gynaecological Oncology

Volumn 21, Issue 1, 2000, Pages 84-85

  Cacciari, N ^a   Zamagni, C ^a   Martoni, Andrea ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Carboplatin; Ovarian cancer; Paclitaxel; Polychemotherapy; Topotecan

Indexed keywords

CARBOPLATIN; PACLITAXEL; TOPOTECAN;

ARTICLE; BONE MARROW; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CLINICAL TRIAL; DRUG TOLERABILITY; EPITHELIUM CELL; FEMALE; HUMAN; NEUTROPENIA; OVARY CANCER; PERIPHERAL BLOOD STEM CELL; PHASE 1 CLINICAL TRIAL; THROMBOCYTOPENIA;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MIDDLE AGED; NEUTROPENIA; OVARIAN NEOPLASMS; PACLITAXEL; THROMBOCYTOPENIA; TOPOTECAN;

EID: 0033965662     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. ten Bokkel Huinink W. W. Gore M., Carmichael J. et al.: "Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer". J. Clin. Oncol. 1997, 15, 2183.
2. Zamagni C., Martoni A., Cacciari N., Gentile A. and Pannuti F: "The combination of paclitaxel and carboplatin as first line chemotherapy in patients with stage III and IV ovarian cancer: a phase I-II study". Am. J. Clin. Oncol., 1998, 21, 491.
3. Armstrong D. K., O'Reilly S., Bookman M. et al.: "A phase I study of topotecan, cisplatin and paclitaxel in newly diagnosed epithelial ovarian cancer, a Gynecologic Oncology Group (GOG 9602) study". Proceedings of ASCO, 17 (abst. 1351) 1998.
4. ten Bokkel Huinink W. W., Richel D. J., Herben V. M. M. et al.: "Feasibility study of the combination of cisplatin, paclitaxel and topotecan in ovarian cancer patients". Proceedings of ASCO 17 (abst. 1353) 1998.
5. Schilder R. J., Gallo J. M., Johnson S. W. et al.: "Phase I study of multiple cycles of high dose topotecan, carboplatin and paclitaxel with peripheral blood stem cell support". Proceedings of ASCO 17 (abst. 290) 1998.