Pathogenic mechanism of mouse brain damage caused by oral infection with Shiga toxin-producing Escherichia coli O157:H7

Infection and Immunity

Volumn 68, Issue 3, 2000, Pages 1207-1214

  Kita, Eiji ^a   Yunou, Yoshihisa ^a   Kurioka, Takaaki ^a   Harada, Hiroko ^a   Yoshikawa, Shinji ^a   Mikasa, Keiichi ^a   Higashi, Nobutaka ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SHIGA TOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; BRAIN INJURY; CYTOKINE PRODUCTION; ESCHERICHIA COLI; FEMALE; HISTOPATHOLOGY; MOUSE; MOUTH INFECTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BACTERIAL TOXINS; BRAIN; CYTOKINES; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI O157; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; SHIGA TOXINS; TRIHEXOSYLCERAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033964155     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.3.1207-1214.2000     Document Type: Article

References (39)

1. Brodin, N. T., J. Dahmén, B. Nilsson, L. Messeter, S. Martensson, J. Heldrup, H. O. Sjögren, and A. Lundblad. 1988. Monoclonal antibodies produced by immunization with neoglycoproteins containing Galα1-4Galβ1-4Glc-O and Galα1-4Galβ1-4GlcNAc-O residues: useful immunochemical and cytochemical reagents for blood group P antigens and a differentiation marker in Burkitt lymphoma and other B-cell malignancies. Int. J. Cancer 42:185-194.
2. Fujii, J., T. Kita, S. Yoshida, T. Takeda, H. Kobayashi, N. Nakata, K. Ohsato, and Y. Mizuguchi. 1994. Direct evidence of neuron impairment by oral infection with verotoxin-producing Escherichia coli O157:H- in mitomycin-treated mice. Infect. Immun. 62:3447-3453.
3. Fujii, J., Y. Kinoshita, T. Kita, A. Higure, T. Takeda, N. Tanaka, and S. Yoshida. 1996. Magnetic resonance imaging and histopathological study of brain lesions in rabbits given intravenous verotoxin 2. Infect. Immun. 64: 5053-5060.
4. Fujii, J., Y. Kinoshita, Y. Yamada, T. Yutsudo, T. Kita, T. Takeda, and S. Yoshida. 1998. Neurotoxicity of intrathecal Shiga toxin 2 and protection by intrathecal injection of anti-Shiga toxin 2 antiserum in rabbits. Microb. Pathog. 25:139-146.
5. Garred, Ø., E. Dubinina, P. K. Holm, S. Olsnes, B. Deurs, J. V. Kozlov, and K. Sandvig. 1995. Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants. Exp. Cell Res. 218:39-49.
6. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
7. Glaser, B. A., P. A. D'Amore, R. G. Michels, A. Patz, and A. Fenslau. 1980. Demonstration of vasoproliferative activity from mammalian retina. J. Cell Biol. 84:298-304.
8. Hamano, S., Y. Nakanishi, T. Nara, T. Seki, T. Ohtani, T. Oishi, K. Joh, T. Oikawa, Y. Muramatsu, Y. Ogawa, and S. Akashi. 1993. Neurological manifestations of hemorrhagic colitis in the outbreak of Escherichia coli O157:H7 infection in Japan. Acta Pediatr. 82:454-458.
9. Harel, Y., M. Silva, B. Giroir, A. Weinberg, T. B. Cleary, and B. Beutler. 1993. A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by Shiga-like toxin. J. Clin. Investig. 92:2110-2116.
10. Hogan, M. M., P. Y. Perera, and S. N. Vogel. 1989. Examination of macrophage cell surface antigen regulation by rIFN-γ and IFN-α/β utilizing digital imaging by a novel laser detection system. Anchored cell analysis station (ACAS) 470. J. Immunol. Methods 123:9-18.
11. Isogai, E., H. Isogai, K. Kimura, S. Hayashi, T. Kubota, N. Fujii, and K. Takeshi. 1998. Role of tumor necrosis factor alpha in gnotobiotic mice infected with an Escherichia coli O157:H7 strain. Infect. Immun. 66:197-202.
12. Karmali, M. A. 1989. Infection by verocytotoxin-producing Escherichia coli. Clin. Microbiol. Rev. 2:15-38.
13. Karpman, D., H. Cornell, M. Svensson, F. Scheutz, P. Alm, and C. Svanborg. 1997. The role of lipopolysaccharide and Shiga-like toxin in a mouse model of Escherichia coli O157:H7 infection. J. Infect. Dis. 175:611-620.
14. Kaye, S. A., C. B. Louise, B. Boyd, C. A. Lingwood, and T. G. Obrig. 1993. Shiga toxin-associated hemolytic uremic syndrome: interleukin-1β enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro. Infect. Immun. 61:3886-3891.
15. Kundu, S. K. 1981. DEAE-silica gel and DEAE-controlled porous glass as ion exchangers for the isolation of glycolipids. Methods Enzymol. 72:174-185.
16. Kurioka, T., Y. Yunou, and E. Kita. 1998. Enhancement of susceptibility to Shiga toxin-producing Escherichia coli O157:H7 by protein calorie malnutrition in mice. Infect. Immun. 66:1726-1734.
17. Ladisch, S., and B. Gillard. 1985. A solvent partition method for microscale ganglioside purification. Anal. Biochem. 146:220-231.
18. Louise, C. B., and T. G. Obrig. 1991. Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1β, and tumor necrosis factor alpha on human vascular endothelial cells in vitro. Infect. Immun. 59:4173-4179.
19. Lucas, R., I. Garcia, Y. R. A. Donati, M. Hribar, S. J. Mandriota, C. Giroud, W. A. Buurman, L. Fransen, P. M. Suter, G. Nuñez, M. S. Pepper, and G. E. Grau. 1998. Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cell. Eur. J. Immunol. 28:3577-3586.
20. Mangeney, M., C. A. Lingwood, S. Taga, B. Caillou, T. Tursz, and J. Wiels. 1993. Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen. Cancer Res. 53:5314-5319.
21. Murata, A., T. Shimazu, T. Yamamoto, N. Taenaka, K. Nagayama, T. Honda, H. Sugimoto, M. Monden, N. Matsuura, and S. Okada. 1998. Profiles of circulating inflammatory-and anti-inflammatory cytokines in patients with hemolytic uremic syndrome due to E. coli O157 infection. Cytokine 10: 544-548.
22. Obrig, T. G., C. B. Louise, C. A. Lingwood, B. Boyd, L. Barley-Maloney, and T. O. Daniel. 1993. Endothelial heterogeneity in Shiga toxin receptors and responses. J. Biol. Chem. 268:15484-15488.
23. Pai, C. H., J. K. Kelly, and G. L. Meyers. 1986. Experimental infection of infant rabbits with verotoxin-producing Escherichia coli. Infect. Immun. 51: 16-23.
24. Pober, J. S. 1998. Activation and injury of endothelial cells by cytokines. Pathol. Biol. 46:159-163.
25. Polunovsky, V. A., C. H. Wendt, D. H. Ingbar, and M. S. Peterson. 1994. Induction of endothelial cell apoptosis by TNF-α: modulation by inhibitors of protein synthesis. Exp. Cell Res. 214:584-594.
26. Richardson, S. E., T. A. Rotman, V. Jay, C. R. Smith, L. F. Becke, M. Petric, N. F. Olivieri, and M. A. Karmali. 1992. Experimental verocytotoxemia in rabbits. Infect. Immun. 60:4154-4167.
27. Saito, T., and S. Hakomori. 1971. Quantitative isolation of total glycosphingolipids from animal cells. J. Lipid Res. 12:257-259.
28. Sandvig, K., Ø. Garred, K. Prydz, J. V. Kozlov, S. H. Hansen, and B. van Deurs. 1992. Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature 358:510-512.
29. Sharefkin, J. B., K. D. Fairchild, R. A. Albus, D. F. Cruess, and N. M. Rich. 1986. The cytotoxic effect of surgical glove powder particles on adult human vascular endothelial cell cultures: implications for clinical uses of tissues culture techniques. J. Surg. Res. 41:463-472.
30. Taga, S., K. Carlier, Z. Mishal, C. Capoulade, and M. Mangeney. 1997. Intracellular signaling events in CD77-mediated apoptosis of Burkitt's lymphoma cells. Blood 90:2757-2767.
31. Tesh, V. L., J. E. Samuel, L. P. Perera, J. B. Sharefkin, and A. D. O'Brien. 1991. Evaluation of the role of Shiga and Shiga-like toxins in mediating direct damage to human vascular endothelial cells. J. Infect. Dis. 164:344-352.
32. Tzipori, S., C. W. Chow, and H. R. Powell. 1988. Cerebral infection with Escherichia coli O157:H7 in humans and gnotobiotic piglets. J. Clin. Pathol. 41:1099-1103.
33. Tzipori, S., K. I. Wachsmuth, C. Chapman, R. Birner, J. Brittinghan, C. Jackson, and J. Hogg. 1986. Studies on the pathogenesis of hemorrhagic colitis caused by Escherichia coli O157:H7 in gnotobiotic piglets. J. Infect. Dis. 154:712-716.
34. Van De Kar, N. C. A. J., T. Kooistra, M. Vermeer, W. Lesslauer, L. A. H. Monnens, and V. W. M. van Hinsbergh. 1995. Tumor necrosis factor-alpha induces endothelial galactosyl transferase activity and verocytotoxin receptors. Role of specific tumor necrosis factor receptors and protein kinase C. Blood 85:734-743.
35. Wadolkowski, E. A., J. A. Burris, and A. D. O'Brien. 1990. Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 58:2438-2445.
36. Wadolkowski, E. A., L. M. Sung, J. A. Burris, J. E. Samuel, and A. D. O'Brien. 1990. Acute renal tubular necrosis and death of mice orally infected with Escherichia coli strains that produce Shiga-like toxin type II. Infect. Immun. 58:3959-3965.
37. Weinberg, D. S., K. A. Ault, M. Gurley, and G. S. Pinkus. 1986. The human lymph node germinal center cell: characterization and isolation by using two-color flow cytometry. J. Immunol. 137:1486-1494.
38. Woods, K. M., and S. K. Chapes. 1993. Three distinct cell phenotype of induced TNF cylotoxicity and their relationship to apoptosis. J. Leukoc. Biol. 53:37-44.
39. Yutsudo, T., N. Nakabayashi, T. Hirayama, and Y. Takeda. 1987. Purification and some properties of a Vero toxin from Escherichia coli O157:H7 that is immunologically unrelated to Shiga toxin. Microb. Pathog. 3:21-30.