Genetic engineering of glycinebetaine synthesis in plants: Current status and implications for enhancement of stress tolerance

Journal of Experimental Botany

Volumn 51, Issue 342, 2000, Pages 81-88

  Sakamoto, Atsushi ^a   Murata, Norio ^a  

^a NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

Compatible solute; Genetic engineering; Glycinebetaine; Stress tolerance; Transgenic plants

Indexed keywords

ARTHROBACTER; BIOACCUMULATION; BIOSYNTHESIS; COLD TOLERANCE; COMPLEMENTARY DNA; ESCHERICHIA COLI; GENETIC ENGINEERING; GLYCINEBETAINE; SALINITY; STRESS TOLERANCE; SURVIVAL;

ARTHROBACTER; ARTHROBACTER GLOBIFORMIS; EMBRYOPHYTA; ESCHERICHIA COLI; MIMOSA; SPINACIA OLERACEA;

EID: 0033963992     PISSN: 00220957     EISSN: None     Source Type: Journal    
DOI: 10.1093/jxb/51.342.81     Document Type: Article

References (49)

1. Allard F, Houde M, Krol M, Ivanov A, Huner NPA, Sarhan F. 1998. Betaine improves freezing tolerance in wheat. Plant and Cell Physiology 39, 1194-1202.
2. Alia, Hayashi H, Chen THH, Murata N. 1998a. Transformation with a gene for choline oxidase enhances the cold tolerance of Arabidopsis during germination and early growth. Plant, Cell and Environment 21, 232-239.
3. Alia, Hayashi H, Sakamoto A, Murata N. 1998b. Enhancement of the tolerance of Arabidopsis to high temperatures by genetic engineering of the synthesis of glycinebetaine. The Plant Journal 16, 155-161.
4. Alia, Kondo Y, Sakamoto A, Nonaka H, Hayashi H, Saradhi PP, Chen THH, Murata N. 1999. Enhanced tolerance to light stress of transgenic Arabidopsis plants that express the cod A gene for a bacterial choline oxidase. Plant Molecular Biology 40, 279-288.
5. Arakawa K, Katayama M, Takabe T. 1990. Levels of betaine in green leaves and etiolated leaves and roots of barley. Plant and Cell Physiology 31, 797-803.
6. Bohnert HJ, Jensen RG. 1996. Strategies for engineering water-stress tolerance in plants. Trends in Biotechnology 14, 89-97.
7. Bohnert HJ, Nelson DE, Jensen RG. 1995. Adaptations to environmental stresses. The Plant Cell 7, 1099-1111.
8. Boyer JS. 1982. Plant productivity and environment. Science 218, 443-448.
9. Brouquisse R, Weigel P, Rhodes D, Yocum CF, Hanson AD. 1989. Evidence for a ferredoxin-dependent choline mono-oxygenase from spinach chloroplast stroma. Plant Physiology 90, 322-329.
10. Deshnium P, Los DA, Hayashi H, Mustardy L, Murata N. 1995. Transformation of Synechococcus with a gene for choline oxidase enhances tolerance to salt stress. Plant Molecular Biology 29, 897-907.
11. Gorham J. 1995. Betaines in higher plants - biosynthesis and role in stress metabolism. In: Wallsgrove RM, ed. Amino acids and their derivatives in higher plants. Cambridge: Cambridge University Press, 171-203.
12. Grumet R, Hanson AD. 1986. Genetic evidence for an osmoregulatory function of glycinebetaine accumulation in barley. Australian Journal of Plant Physiology 13, 353-364.
13. Hanson AD, May AM, Grumet R, Bode J, Jamieson GC, Rhodes D. 1985. Betaine synthesis in Chenopods: localization in chloroplasts. Proceedings of the National Academy of Sciences, USA 82, 3678-3682.
14. Harinasut P, Tsutsui K, Takabe T, Nomura M, Takabe T, Kishitani S. 1996. Exogenous glycinebetaine accumulation and increased salt-tolerance in rice seedlings. Bioscience, Biotechnology, and Biochemistry 60, 366-368.
15. Hayashi H, Alia, Mustardy L, Deshnium P, Ida M, Murata N. 1997. Transformation of Arabidopsis thaliana with the codA gene for choline oxidase; accumulation of glycinebetaine and enhanced tolerance to salt and cold stress. The Plant Journal 12, 133-142.
16. Hayashi H, Alia, Sakamoto A, Nonaka H, Chen THH, Murata N. 1998. Enhanced germination under high-salt conditions of seeds of transgenic Arabidopsis with a bacterial gene (codA) for choline oxidase. Journal of Plant Research 111, 357-362.
17. Hayashi H, Murata N. 1998. Genetically engineered enhancement of salt tolerance in higher plants. In: Satoh K, Murata N, eds. Stress responses of photosynthetic organisms. Amsterdam: Elsevier, 133-148.
18. Holmstrøm K-O, Welin B, Mandal A, Kristiansdottir I, Teeri TH, Lamark T, Strøm AR, Palva ET. 1994. Production of the Escherichia coli glycinebctaine-aldehyde dehydrogenase, an enzyme required for the synthesis of the osmoprotectant glycine betaine, in transgenic plants. The Plant Journal 6, 749-758.
19. Ikuta S, Mamura S, Misaki H, Horiuti Y. 1977. Purification and characterization of choline oxidase from Arthrobacter globiformis. Journal of Biochemistry 82, 1741-1749.
20. Ishitani M, Arakawa K, Mizuno S, Kishitani S, Takabe T. 1993. Betaine aldehyde dehydrogenase in the Gramineae - levels in leaves of both betaine-accumulating and nonaccumulating cereal plants. Plant and Cell Physiology 34, 493-495.
21. Ishitani M, Nakamura T, Han SY, Takabe T. 1995. Expression of the betaine aldehyde dehydrogenase gene in barley in response to osmotic stress and abscisic acid. Plant Molecular Biology 27, 307-315.
22. Itai C, Paleg LG. 1982. Responses of water-stressed Hordeum distichum L. and Cucumis sativus to proline and betaine. Plant Science Letters 25, 329-335.
23. Kishitani S, Watanabe K, Yasuda S, Arakawa K, Takabe T. 1994. Accumulation of glycinebetaine during cold acclimation and freezing tolerance in leaves of winter and spring barley plants. Plant. Cell and Environment 17, 89-95.
24. Lamark T, Kaasen I, Eshoo MW, Falkenberg P, McDougall J, Strøm AR. 1991. DNA sequence and analysis of the bet genes encoding the osmoregulatory choline-glycine betaine pathway of Escherichia coli. Molecular Microbiology 5, 1049-1064.
25. Landfald B, Strom AR. 1986. Choline-glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli. Journal of Bacteriology 165, 849-855.
26. Le Rudulier D, Strøm AR, Dandekar AM, Smith LT, Valentaine RC. 1984. Molecular biology of osmoregulation. Science 224, 1064-1068.
27. Lilius G, Holmberg N, Bülow L. 1996. Enhanced NaCl stress tolerance in transgenic tobacco expressing bacterial choline dehydrogenase. Bio/Technology 14, 177-180.
28. Mäkelä P, Mantila J, Hinkkanen R, Pehu E, Peltonen-Sainio P. 1996. Effect of foliar applications of glycinebetaine on stress tolerance, growth, and yield of spring cereals and summer turnip rape in Finland. Journal of Agronomy & Crop Science 176, 223-234.
29. Matoh T, Watanabe J, Takahashi E. 1987. Sodium, potassium, chloride, and betaine concentrations in isolated vacuoles from salt-grown Atriplex gmelini leaves. Plant Physiology 84, 173-177.
30. McCue KF, Hanson AD. 1990. Drought and salt tolerance: towards understanding and application. Trends in Biotechnology 8, 358-362.
31. Nakamura T, Yokota S, Muramoto Y, Tsutsui K, Oguri Y, Fukui K, Takabe T. 1997. Expression of a betaine aldehyde dehydrogenase gene in rice, a glycinebetaine nonaccumulator, and possible localization of its protein in peroxisomes. The Plant Journal 11, 1115-1120.
32. Nishida I, Murata N. 1996. Chilling sensitivity in plants and cyanobacteria: The crucial contribution of membrane lipids. Annual Review of Plant Physiology and Plant Molecular Biology 47, 541-568.
33. Nomura M, Ishitani M, Takabe T, Rai AK, Takabe T. 1995. Synechococcus sp. PCC7942 transformed with Escherichia coli bet genes produces glycine betaine from choline and acquires resistance to salt stress. Plant Physiology 107, 703-708.
34. Nuccio ML, Russell BL, Nolte KD, Rathinasabapathi B, Gage DA, Hanson AD. 1998. The endogenous choline supply limits glycine betaine synthesis in transgenic tobacco expressing choline monooxygenase. The Plant Journal 16, 487-496.
35. Papageorgiou GC, Murata N. 1995. The unusually strong stabilizing effects of glycine betaine on the structure and function of the oxygen-evolving photosystem II complex. Photosynthesis Research 44, 243-252.
36. Rajendrakumar CSV, Suryanarayana T, Reddy AR. 1997. DNA helix destabilization by prolinc and betaine: possible role in the salinity tolerance process. FEBS Letters 410, 201-205.
37. Rathinasabapathi B, Burnet M, Russel BL, Gage DA, Liao P-C, Nye GJ, Scott P, Golbeck JH, Hanson AD. 1997. Choline monooxygenase, an unusual iron sulphur enzyme catalyzing the first step of glycine betaine synthesis in plants: prosthetic group characterization and cDNA cloning. Proceedings of the National Academy of Sciences, USA 94, 3454-3458.
38. Rathinasabapathi B, Gage DA, Mackill DJ, Hanson AW. 1993. Cultivated and wild rices do not accumulate glycinebetaine due to deficiencies in two biosynthetic steps. Crop Science 33, 534-538.
39. Rathinasabapathi B, McCue KF, Gage DA, Hanson AD. 1994. Metabolic engineering of glycine betaine synthesis: plant glycinebetaine aldehyde dehydrogenases lacking typical transit peptides are targeted to tobacco chloroplasts where they confer glycinebetaine aldehyde resistance. Planta 193, 155-162.
40. Rhodes D, Hanson AD. 1993. Quaternary ammonium and tertiary sulphonium compounds in higher plants. Annual Review of Plain Physiology and Plant Molecular Biology 44, 357-384.
41. Rhodes D, Pich PJ, Brunk DG, Ju GC, Rhodes JC, Pauly MH, Hansen LA. 1989. Development of two isogenic sweet corn hybrids differing for glycinebetaine content. Plant Physiology 91, 1112-1121.
42. Sakamoto A, Alia, Murata N. 1998. Metabolic engineering of rice leading to biosynthesis of glycinebetaine and tolerance to salt and cold. Plant Molecular Biology 38, 1011-1019.
43. Saneoka H, Nagasaka C, Hahn DT, Yang W-J, Premachandra GS, Joly RJ, Rhodes D. 1995. Salt tolerance of glycinebetaine-deficient and -containing maize lines. Plant Physiology 107, 631-638.
44. Trossat C, Rathinasabapathi B, Hanson AD. 1997. Transgenically expressed betaine aldehyde dehydrogenase efficiently catalyzes oxidation of dimethylsulphoniopropionaldehyde and ω-aminoaldehydes. Plant Physiology 113, 1457-1461.
45. Weigel P, Weretilnyk EA, Hanson AD. 1986. Betaine aldehyde oxidation by spinach chloroplasts. Plant Physiology 82, 753-759.
46. Weretilnyk EA, Bednarek S, McCue KF, Rhodes D, Hanson AD. 1989. Comparative biochemical and immunological studies of the glycine betaine synthesis pathway in diverse families of dicotyledons. Planta 178, 342-352.
47. Weretilnyk EA, Hanson AD. 1990. Molecular cloning of a plant betaine-aldehyde dehydrogenase, an enzyme implicated in adaptation to salinity and drought. Proceedings of the National Academy of Sciences, USA 87, 2745-2749.
48. Wilken DR, McMacken ML, Rodriquez A. 1970. Choline and betaine aldehyde oxidation by rat liver mitochondria. Biochimica et Biophysica Acta 216, 305-317.
49. Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN. 1982. Living with water stress: evolution of osmolyte systems. Science 217, 1214-1222.