Free radicals are involved in the damage to protein synthesis after anoxia/aglycemia and NMDA exposure

Brain Research

Volumn 857, Issue 1-2, 2000, Pages 172-182

  Monje, Michelle L ^a   Chatten Brown, Justin ^a   Hye, Scott E ^a   Raley Susman, Kathleen M ^a  

^a VASSAR COLLEGE   (United States)

Author keywords

Anoxia aglycemia; Free radical; N Acetylcysteine; N Methyl D Aspartate; Protein synthesis; Vitamin E

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID; CALCIUM; FREE RADICAL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SCAVENGER; XANTHINE; XANTHINE OXIDASE;

ANIMAL TISSUE; ANOXIA; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL DEATH; CONTROLLED STUDY; DOSE RESPONSE; HIPPOCAMPUS; HYPOGLYCEMIA; HYPOXIA; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; ANOXIA; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FREE RADICAL SCAVENGERS; FREE RADICALS; HIPPOCAMPUS; HYPOGLYCEMIA; MALE; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; VITAMIN E;

EID: 0033963703     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02404-X     Document Type: Article

References (57)

1. Acosta D., Kass I.S., Cottress J.E. Effect of a-tocopherol and free radicals on anoxic damage in the rat hippocampal slice. Exp. Neurol. 97:1987;607-614.
2. Barth A., Barth L., Newell D.W. Combination therapy with MK-801 and a-phenyl-tert-butyl-nitrone enhances protection against ischemic neuronal damage in organotypic hippocampal slice cultures. Exp. Neurol. 141:1996;330-336.
3. Beck T., Wree A., Schleicher A. Glucose utilization in rat hippocampus after long-term recovery from ischemia. J. Cereb. Blood Flow Metab. 10:1990;542-549.
4. Bodsch W., Barbier A., Oehmichen M., Grosse-Ophoff B., Hossmann K.-A. Recovery of monkey brain after prolonged ischemia: II. Protein synthesis and morphological alterations. J. Cereb. Blood Flow Metab. 6:1986;22-33.
5. Braughler J.M., Duncan L.A., Goodman T. Calcium enhances in vitro free radical-induced damage to brain synaptosomes, mitochondria and cultured spinal cord neurons. J. Neurochem. 45:1985;1288-1293.
6. Brostrom C.O., Brostrom M.A. Calcium-dependent regulation of protein synthesis in intact mammalian cells. Annu. Rev. Physiol. 52:1990;577-590.
7. Carter A.J., Muller R.E. Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices. J. Neurochem. 57:1991;888-896.
8. Carter A.J., Muller R.E., Pschorn U., Stransky W. Preincubation with creatine enhances levels of creatine phosphate and prevents anoxic damage in rat hippocampal slices. J. Neurochem. 64:1995;2691-2699.
9. Choi D.W., Maulucci-Gedde M., Kriegstein R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
10. Clemens M.J. Regulatory mechanisms in translational control. Curr. Opin. Cell Biol. 1:1989;1160-1197.
11. Cooper H.K., Zalewska T., Kawakami S., Hossmann K.-A., Kleihues P. The effect of ischemia and recirculation on protein synthesis in the rat brain. J. Neurochem. 28:1977;929-934.
12. DeGracia D.J., Neumar R.W., White B.C., Krause G.S. Global brain ischemia and reperfusion: Modifications in eukaryotic initiation factors associated with inhibition of translation initiation. J. Neurochem. 67:1996;2005-2012.
13. Djuricic B., Gohn G., Paschen W., Hossmann K.A. Calcium activity and post-ischemic suppression of protein synthesis. Experientia. 51:1995;245-248.
14. Dumuis A., Sebben M., Haynes L., Pin J.P., Bockaert J. NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Nature. 336:1988;68-70.
15. 2+ account for poor pyramidal cell structure in hippocampal slices. J. Neurochem. 55:1990;473-483.
16. Furata S., Ohta S., Hatakeyama T., Nakamura K., Sakaki S. Recovery of protein synthesis in tolerance-induced hippocampal CA1 neurons after transient forebrain ischemia. Acta Neurol. (Berlin). 86:1993;329-336.
17. Gill R., Foster A.C., Woodruff G.N. Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil. J. Neurosci. 7:1987;3343-3349.
18. Grotta J.C., Picone C.M., Dedman J.R., Rhoades H.M., Strong R.A., Earls R.M., Yao L.P. Neuronal protection correlates with prevention of calcium-calmodulin binding in rats. Stroke. 21:1990;28-31.
19. Hossmann K.A. Disturbances of cerebral protein synthesis in global and ischemic cell death. Prog. Brain Res. 96:1993;161-177.
20. Hu B.R., Wieloch T. Stress-induced inhibition of protein synthesis initiation: modulation of initiation factor 2 and guanine nucleotide exchange factor activities following transient cerebral ischemia in the rat. J. Neurosci. 13:1993;1830-1838.
21. Ikeda M., Yoshida S., Busto R., Santiso M., Ginsberg M.D. Polyphosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia. J. Neurochem. 47:1986;123-132.
22. Kellogg E.W., Fridovich I. Liposome oxidation and erythrocyte lysis by enzymatically generated superoxide and hydrogen peroxide. J. Biol. Chem. 252:1977;6721-6728.
23. Kitigawa K., Matsumoto M., Niinobe M., Mikoshiba K., Hata R., Ueda H., Handa N., Fukunaga R., Isaka Y., Kimura K., Kamada T. Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage: immunohistochemical investigation of dendritic damage. Neuroscience. 31:1989;401-411.
24. Lafon-Cazal M., Pietri S., Culcasi M., Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature. 364:1993;535-537.
25. Lipton P., Heimbach C.J. Mechanism of extracellular potassium stimulation of protein synthesis in the in vitro hippocampus. J. Neurochem. 31:1978;1299-1307.
26. Lobner D., Lipton P. Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: relationship to electrophysiological damage. J. Neurosci. 13:1993;4861-4871.
27. Lust W.D., Feussner G.K., Barbehenn E.K., Passonneau J.V. The enzymatic measurement of adenine nucleotides and P-creatine in picomole amounts. Anal. Biochem. 110:1981;258-266.
28. Majewska M.D., Bell J.A. Ascorbic acid protects neurons from injury induced by glutamate and NMDA. NeuroReport. 1:1990;194-196.
29. Majewska M.D., Bell J.A., London E.D. Regulation of the NMDA receptor by redox phenomena: inhibitory role of ascorbate. Brain Res. 537:1990;328-332.
30. Matesic D.F., Lin R.C.S. Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain. J. Neurochem. 63:1994;1012-1020.
31. McCord J.M. Superoxide radical: A likely link between reperfusion injury and inflammation. Adv. Free Radical Biol. Med. 2:1986;325-345.
32. Michaels R.L., Rothman S.M. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J. Neurosci. 10:1990;283-292.
33. Novelli A., Reilly J.A., Lysko P.G., Henneberry R.C. Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res. 451:1988;205-212.
34. Patel M., Day B.J., Crapo J.D., Fridovich I., McNamara J.O. Requirement for superoxide in excitotoxic cell death. Neuron. 16:1996;345-355.
35. Pellegrini-Giampietro D.E., Cherici G., Alesiani M., Carla V., Moroni F. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 10:1990;1035-1041.
36. Pellegrini-Giampietro D.E., Cozzi A., Moroni F. The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil. Neuroscience. 63:1994;701-709.
37. Pellerin L., Wolfe L.S. Release of arachidonic acid by NMDA receptor activation in the rat hippocampus. Neurochem. Res. 16:1991;983-989.
38. Pelligrini-Giampietro D.E., Cherici G., Alesiani M., Carla V., Moroni F. Excitatory amino acid release from rat hippocampal slices as a consequence of free radical formation. J. Neurochem. 51:1988;1960-1963.
39. Raley-Susman K.M., Barnes J.R. The effects of extracellular pH and calcium manipulation on protein synthesis and response to anoxia/aglycemia in the rat hippocampal slice. Brain Res. 782:1998;281-289.
40. Raley-Susman K.M., Barnes J.R., Kaja J. Effects of volatile anesthetics on hippocampal slice metabolism, response to anoxia with or without glucose. Brain Res. 755:1997;1-8.
41. Raley-Susman K.M., Lipton P. In vitro ischemia and protein synthesis in the rat hippocampal slice: the role of calcium and NMDA receptor activation. Brain Res. 515:1990;27-38.
42. Raley-Susman K.M., Murata J. Time course of protein changes following in vitro ischemia in the rat hippocampal slice. Brain Res. 694:1995;94-102.
43. Randall R.D., Thayer S.A. Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12:1992;1882-1895.
44. Rice M.E., Perez-Pinzon M.A., Lee E.J.K. Ascorbic acid, but not glutathione, is taken up by brian slices and preserves cell morphology. J. Physiol. 71:1994;1591-1596.
45. Rotman E.I., Brostrom M.A., Brostrom C.O. Inhibition of protein synthesis in intact mammalian cells by arachidonic acid. Biochem. J. 282:1992;487-494.
46. Saez J.C., Kessler J.A., Bennett M.V.L., Spray D.C. Superoxide dismutase protects cultured neurons against death by starvation. PNAS. 84:1987;3056-3059.
47. Schmidt-Kastner R., Freund T.F. Selective vulnerability of the hippocampus in brain ischemia. Neuroscience. 40:1991;599-636.
48. Schurr A., Payne R.S., Rigor B.M. Synergism between diltiazem and MK-801 but not APV in protecting hippocampal slices against hypoxic damage. Brain Res. 684:1995;233-236.
49. Siesjo B.K., Bengtsson F. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab. 9:1989;127-140.
50. Smith D.S., Rehncrona S., Siesjo B.K. Barbiturates as protective agents in brain ischemia and as free radical scavengers in vitro. Acta Physiol. Scand. Suppl. 492:1980;129-134.
51. + channels, glutamate release, and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. J. Neurosci. 16:1996;5004-5013.
52. Vornov J.J., Coyle J.T. Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice. J. Neurochem. 56:1991;996-1006.
53. Wauquier A., Ashton D., Clincke G., Fransen J. "Calcium entry blockers" as cerebral protecting agents: comparative activity in tests of hypoxia and hyperexcitability. Jpn. J. Pharmacol. 38:1985;1-7.
54. White B.C., Daya A., DeGracia D.J., O'Neil B.J., Skjaerlund J.M., Krause G.S., Rafols J.A. Fluorescent histochemical localization of lipid peroxidation during brain reperfusion following cardiac arrest. Acta Neuropathol. (Berlin). 86:1993;1-9.
55. Whittingham T.S., Assaf H., Selman W.R., Ratcheson R.A., Lust W.D. Glutamate-induced energetic stress in hippocampal slices: evidence against NMDA and glutamate uptake as mediators. Met. Brain Dis. 7:1992;77-91.
56. Whittingham T.S., Lust W.D., Passonneau J.V. An in vitro model of ischemia: metabolic and electrical alterations in the hippocampal slice. J. Neurosci. 4:1984;793-802.
57. Yamashima T., Saido T.C., Takita M., Miyazawa A., Yamano J., Miyakawa A., Nishijyo H., Yamashita J., Kawashima S., Ono T., Yoshioka T. Transient brain ischaemia provokes Ca2+, PIP2 and calpain responses prior to delayed neuronal death in monkeys. Eur. J. Neurosci. 8:1996;1932-1944.