Lack of mucin MUC5AC field change expression associated with tubulovillous and villous colorectal adenomas

Journal of Clinical Pathology

Volumn 53, Issue 2, 2000, Pages 100-104

  Longman, R J ^a   Douthwaite, J ^a   Sylvester, P A ^a   O'Leary, D ^a   Warren, B F ^b   Corfield, A P ^a   Thomas, M G ^a  

^a BRISTOL ROYAL INFIRMARY   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Colorectal adenoma; Field change; Gene expression; Mucin

Indexed keywords

MESSENGER RNA; MUCIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON ADENOMA; COLON BIOPSY; CONTROLLED STUDY; EXCISION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RECTUM ADENOMA; RECTUM BIOPSY; SIGMOIDOSCOPY; TUMOR RECURRENCE; VILLOUS ADENOMA;

ADENOMA, VILLOUS; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; INTESTINAL MUCOSA; MALE; MIDDLE AGED; MUCINS; NEOPLASM PROTEINS; NEOPLASM RECURRENCE, LOCAL; PROSPECTIVE STUDIES; RECTUM; TUMOR MARKERS, BIOLOGICAL;

EID: 0033963663     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.53.2.100     Document Type: Article

References (40)

1. 1 Morson BC, Sobin LH. International classification of tumours No 15. Histological typing of intestinal tumours. Geneva: WHO, 1976.
2. 2 Pollard SG, MacFarlane R, Everett WG. Villous tumours of the large bowel. Br J Surg 1988;75:910 12.
3. 3 Jahadi MR, Baldwin A. Villous adenomas of the colon and rectum. Am J Surg 1975;130:729 32.
4. 4 Sakamoto GD, Mackeigon JM, Senagore AJ. Trans-anal excision of large rectal villous adenomas. Dis Colon Rectum 1991;34:880-5.
5. 5 Steel RJC, Hershman MJ, Mortensen NJMcC, et al. Trans-anal endoscopic microsurgery initial experience from three centres in the United Kingdom. Br J Surg 1996;83 207-10.
6. 6 Mason AY. Surgical access to the rectum a trans-sphincteric exposure. Proc R Soc Med 1970;63:91 4.
7. 7 Berry AR, Souter RG, Campbell WB, et al. Endoscopic trans-anal resection of rectal tumours - a preliminary report of its use. Br J Surg 1990;77:134-7.
8. 8 Buess GR, Mentego B. Trans-anal endoscopic microsurgery (TEM). Min Invas Ther 1992;1:101 9.
9. 9 Thomson JP. Treatment of sessile villous and tubulovillous adenomas of the rectum. Experience of St Mark's Hospital. Dis Colon Rectum 1977:20:467-72.
10. 10 Filipe MI, Branfoot AC. Abnormal patterns of mucous secretion in apparently normal mucosa of large intestine with carcinoma. Cancer 1984;34:282-90.
11. 11 Yoshikawa R, Utunomiya J. Cell proliferation kinetics in transitional mucosa. Br J Surg 1996;83:36-9.
12. 12 Dawson PA, Filipe MI. An ultrastructural and histochemical study of mucus membrane adjacent to and remote from carcinoma of the colon. Cancer 1976;37:2388-98.
13. 13 Van Klinken BJW, Dekker J, Buller HA et al. Biosynthesis of mucins (MUC2-6) along the longitudinal axis of the human gastrointestinal tract. Am J Physiol 1997; 273(Gastrointest Liver Physiol 36):G296 302.
14. 14 Klomp LWJ, Van Rens L, Strous GJ. Cloning and analysis of human gastric cDNA reveals two types of conserved cysteine-rich domains. Biochem J 1995;308:831-8.
15. 15 Gendler SJ, Lancater C, Taylor-Papadimitriou J, et al. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J Biol Chem 1990;265:15286 93.
16. 16 Gum JR, Hicks JW, Swallow DM, et al. Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. Biochem Biophys Res Commun 1990;171:407 15.
17. 17 Porchet N, Ngyen Van Cong J, Dufosse J, et al. Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandem repeated sequences of 48 base pairs. Biochem Biophys Res Commun 1991;175:414-22.
18. 18 Dufosse J, Porchet N, Audie JP, et al. Degenerate 87-base-pair tandem repeats create hydrophilic/ hydrophobic alternating domains in human peptides mapped to 11p15. Biochem J 1993;293:329-37.
19. 19 Toribara NW, Roberton AM, Ho SB, et al. Human gastric mucin. Identification of a unique species by expression cloning. J Biol Chem 1993;268:5879-85.
20. 20 Bobek LA, Tsai H, Biesbrock RA, et al. Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7). J Biol Chem 1993;268:20563 9.
21. 21 Gum JR, Hicks JW, Toribara NW, et al. Molecular cloning of human intestinal mucin (MUC2) cDNA. J Biol Chem 1994;269:2440-6.
22. 22 Shankar V, Gilmore MS, Elkins RC, et al. A novel human airway mucin cDNA encodes a protein with unique tandem-repeat organization. Biochem J 1994;300:295-8.
23. 23 Meezerman DP, Charles P, Daskal E, et al. Cloning and analysis of a cDNA encoding major airway glycoprotein, human tracheobronchial mucin (MUC5). J Biol Chem 1994;269:12932-9.
24. 24 Guyonnet-Duperat V, Audie J-P, Debailleul V et al. Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes? Biochem J 1995;305:211-19.
25. 25 Pigny P, Guyonnet-Duperat V, Hill AS, et al. Human mucin genes assigned to 11p15.5; identification and organization of a cluster of genes. Genomics 1996;38:340-52.
26. 26 Audie JP, Janin A, Porchet N, et al. Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridisation. J Histochem Cytochem 1993;41:1479-85.
27. 27 Weiss AA, Babyatsky MW, Ogata S, et al. Expression of MUC2 and MUC3 mRNA in human normal, malignant, and inflammatory intestinal tissues. J Histochem Cytochem 1996;44:1161 6.
28. 28 Chang SK, Dohrman AF, Basbaum CB, et al. Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. Gastroenterology 1994;107:28 36.
29. 29 Buisine MP, Janin A, Maunory V, et al. Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma. Gastroenterology 1996;110:84-91.
30. 30 Bartman AE, Sanderson SJ, Ewing SL, et al. Aberrant expression of MUC5AC and MUC6 gastric mucin genes in colorectal polyps. Int J Cancer 1999;80:210-18.
31. 31 Bara J, Gautier R, Daher N, et al. Monoclonal antibodies against oncofetal mucin MI antigens associated with precancerous colonic mucosae. Cancer Res 1986;46:3983-9.
32. 32 Bara J, Chastre E, Mahiou J, et al. Gastric MI mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene. Int J Cancer 1998;75:767-73.
33. 33 Filipe MI. Mucins in the human gastrointestinal tract: a review. Invest Cell Pathol 1979;2:195-216.
34. 34 Jass JR, Allison LJ, Stewart SM, et al. Ulex curopaeus agglutinin-1 binding in hereditary bowel cancer. Pathology 1993;25:114-19.
35. 35 Jass JR. Evolution of hereditary bowel cancer. Murat Res 1993;290:13-25.
36. 36 Boland CR, Sato J, Appelman HD, et al. Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal progression. Nature Med 1995;1:902-7.
37. 37 Habib NA, Dawson PM, Blount MA, et al. Study of the histochemical changes in mucus from normal and tumour bearing mucosa in patients with colorectal cancer. Eur J Surg Oncol 1985;11:243-5.
38. 38 Dawson PM, Habib NA, Rees HC, et al. Mucosal field change in colorectal cancer. Am J Surg 1987;153:281 4.
39. 39 Pilbrow SJ, Herzog PJ, Linnane AW. The adenomacarcinoma sequence in the colorectum - early appearance of a hierarchy of small intestinal mucin antigen (SIMA) epitopes and correlation with malignant potential. Br J Cancer 1992;66:748-57.
40. 40 Kyzer S, Nitmaker B, Gordon PH, et al. Proliferative activity of colonic mucosa at different distances from primary adenocarcinoma as determined by the presence of statin: a nonproliferative-specific nuclear protein. Dis Colon Rectum 1992;35:879-83.