Platelet aggregation during abdominal surgery in an experimental pig model: The effects of presurgical antibiotic protocols and volume replacement with hydroxyethyl starch

Thrombosis Research

Volumn 97, Issue 3, 2000, Pages 143-151

  Frese, Achim ^a   Rinke, Daniela ^a   Künnecke, Martin ^a   Stinner, Benno ^a   Lorenz, Wilfried ^a   Wesemann, Wolfgang ^a   Opper, Claus ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b DRG Instruments   (Germany)

Author keywords

Aggregation; Antibiotics; Hydroxyethyl starch; Platelets; Surgery

Indexed keywords

ADENOSINE DIPHOSPHATE; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; CEFUROXIME; COLLAGEN; HETASTARCH; METRONIDAZOLE; PLASMA SUBSTITUTE;

ABDOMINAL SURGERY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD PRESSURE; CONTROLLED STUDY; HEART RATE; HEMOSTASIS; LAPAROTOMY; NONHUMAN; PRIORITY JOURNAL; SWINE; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT;

ABDOMEN; ADENOSINE DIPHOSPHATE; ANIMALS; ANTIBIOTIC PROPHYLAXIS; BLOOD PRESSURE; BLOOD VOLUME; DISEASE MODELS, ANIMAL; HEART RATE; HEMODILUTION; HETASTARCH; ISOTONIC SOLUTIONS; LAPAROSCOPY; PLATELET AGGREGATION; PLATELET COUNT; SWINE;

EID: 0033963623     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(99)00163-2     Document Type: Article

References (42)

1. McClure P.D., Casserly J.G., Crozier D. Carbenicillin-induced bleeding disorders. Lancet. 19:1970;1307-1308.
2. Fletcher C., Pearson C., Choi S.C., Duma R.J., Evans H.J., Quershi G.D. In vitro comparison of antiplatelet effects of β-lactam penicillins. J Lab Clin Med. 108:1986;217-223.
3. Kariyazono H., Nakamura K., Shinkawa T., Moriyama Y., Toyohira H., Taira A., Yamada K. Inhibitory effects of antibiotics on platelet aggregation in vitro. Hum Exp Toxicol. 16:1997;662-666.
4. Shattil S.J., Bennett J.S., McDonough M., Turnbull J. Carbenicillin and penicillin G inhibit platelet function in vitro by impairing the interaction of agonists with the platelet surface. J Clin Invest. 65:1980;329-337.
5. Burroughs S.F., Johnson G.J. β-Lactam antibiotics inhibit agonist stimulated platelet calcium influx. Thromb Haemost. 69:1993;503-508.
6. Pastakia K.B., Terle D., Prodouz K.N. Penicillin-induced dysfunction of platelet membrane glycoproteins. J Lab Clin Med. 121:1993;546-554.
7. Schermerhorn T., Barr S.C., Stoffregen Dana A., Koren Roth Y., Erb H.N. Whole-blood platelet aggregation, buccal mucosa bleeding time, and serum cephalotin concentration in dogs receiving a presurgical antibiotic protocol. Am J Vet Res. 55:1994;1602-1607.
8. Barr S.C., Ludders J.W., Looney A.L. Platelet aggregation in dogs after sedation with acepromazine and atropine and during subsequent general anaesthesia and surgery. Am J Vet Res. 53:1992;2067-2070.
9. Naesh O., Friis J.T., Hindberg I., Winther K. Platelet function in surgical stress. Thromb Haemost. 54:1985;849-852.
10. Bengtsson A. Cascade system activation in shock. Acta Anesthesiol Scand. 37:1993;7-10.
11. Fukuoka Y., Tachibana T., Yasui A. Anaphylatoxin C3a induces rapid protein phosphorylation in guinea pig platelets. Immunpharmacology. 98:1994;95-104.
12. Strauss R.G. Review of the effects of hydroxyethyl starch on the blood coagulation system. Transfusion. 21:1991;299-301.
13. Vickers J.D., Kinlough Rathbone Raelene L, Mustard F Changes in phosphatidylinositol-4,5-bisphosphate 10 seconds after stimulation of washed rabbit platelets with ADP. Blood. 60:1982;1247-1250.
14. Lorenz W., Barth H., Kusche J., Reimann H.J., Schmal A., Matejka E., Mathias C., Werle E. Histamin in the pig. Determination, distribution, release and pharmacological actions Eur J Pharmacol. 14:1971;155-175.
15. Born G.V.R., Cross H.J. The aggregation of blood platelets. J Physiol. 160:1963;178-195.
16. Fass R.J., Copelan E.A., Brandt J.T., Moeschberger M.L., Ashton J.J. Platelet-mediated bleeding caused by broad-spectrum penicillins. J Infect Dis. 155:1987;1242-1248.
17. Shevchuk Y.M., Conly J.M. Antibiotic-associated hypothrombinemia. A review of prospective studies, 1966-1988 Rev Infect Diseases. 12:1990;1109-1125.
18. Riess H., Braun G., Brehm G., Hiler E. Critical evaluation of platelet aggregation in whole human blood. Am J Clin Pathol. 85:1986;50-56.
19. Bertolini G., Noris P., Balduini C.L. Effect of different sample preparation methods on the results of the impedance technique in the study of platelet hyper- and hypo-function in whole blood. Thromb Res. 71:1993;89-94.
20. Thompson C.B. Selective consumption of large platelets during massive bleeding. Br Med J. 95:1985;291-292.
21. Treib J., Haass A., Pindur G., Wenzel E., Schimrigl K. Blutungskomplikationen durch Hydroxyethylstärke sind vermeidbar. Deutsches Ärzteblatt. 94:1997;2326-2330.
22. Strauss R.G., Stump D.C., Henriksen R.A., Saunders A. Effects of hydroxyethyl starch on fibrinogen, fibrin clot formation, and fibrinolysis. Transfusion. 25:1985;230-234.
23. Stump D.C., Strauss R.G., Henriksen R.A., Petersen R.E., Saunders A. Effects of hydroxyethyl starch on blood coagulation, particularly factor VIII. Transfusion. 25:1985;349-354.
24. MacIntyre E., Mackie I.J., Ho D., Tinker J., Bullen C., Machin S.J. The haemostatic effects of hydroxyethyl starch used as a volume expander. Intensive Care Med. 11:1985;300-303.
25. Lewis J.H., Szeto I.L.F., Bayer W.L., Takaori M., Safar P. Severe hemodilution with hydroxyethyl starch and dextrans. Arch Surg. 93:1966;941-950.
26. Shatney C.H., Deepika K., Militello P.R., Majerus T.C., Dawson B. Efficacy of hetastarch in the resuscitation of patients with multisystem trauma and shock. Arch Surg. 118:1983;804-809.
27. Symington B.E. Hetastarch and bleeding complications. Ann Intern Med. 105:1986;627-628.
28. Damon L., Adams M., Stricker R.B., Ries C. Intracranial bleeding during treatment with hydroxyethyl starch. N Engl J Med. 317:1987;964-965.
29. Cope J.T., Banks D., Mauney M.C., Lucktong T., Shockey K.S., Kron J.L., Tribble C.G. Intraoperative hetastarch infusion impairs hemostasis after cardiac operations. Ann Thorac Surg. 63:1997;78-83.
30. Herwaldt L.A., Swartzendruber S.K., Edmond M.B., Embrey R.P., Wilkerson K.R., Wenzel R.P., Perl T.M. The epidemiology of hemorrhage related to cardiotheracic operations. Infect Control Hosp Epidemiol. 19:1998;9-16.
31. Strauss R.G. Volume replacement and coagulation. A comparative review J Cardiothorac Anesth. 2:1988;24-32.
32. Consensus Conference-Thrombosis and Embolism. Prevention of venous thrombosis and pulmonary embolism. JAMA 1986;256:744-9.
33. Boldt J., Knothe C., Zickmann B., Res P., Dapper F., Hempelmann G. Influence of different intravascular volume therapies on platelet function in patients undergoing cardioplulmonary bypass. Anesth Analg. 76:1993;1185-1190.
34. Tigchelaar I., Gallat Huet R.C.G., Korsten J., Boonstra P.W., Van Oeveren W. Hemostatic effects of three colloid plasma substitutes for priming solution in cardiopulmonary bypass. Eur J Cardio-thoracic Surg. 11:1997;626-632.
35. Treib J., Haass A., Pindur G., Grauer M.T., Treib W., Wenzel E., Schimrigk K. Influence of low and medium molecular weight hydroxyethyl starch on platelets during long-term hemodilution in patients with cerebrovascular disease. Arzneim-Forschung/Drug Res. 46:1996;1064-1066.
36. Vogt N.H., Bothner U., Lerch G., Lindner K.H., Georgieff M. Large dose administration of 6% hydroxyethyl starch 200/0.5 for total hip arthroplasty. Plasma homeostasis, hemostasis, and renal function compared to use of 5% human albumin Anest Analg. 83:1996;262-268.
37. Boldt J., Müller M., Heesen M., Heyn O., Hempelmann G. Influence of different volume therapies on platelet function in the critically ill. Intensive Care Med. 22:1996;1075-1081.
38. Badimon L., Badimon J.J., Turitto V.T., Vallabhajosula S., Fuster V. Platelet thrombus formation on collagen typ I. Circulation. 78:1988;1431-1442.
39. Popov Cenic S., Müller N., Kladetzky R.G., Hack G., Lang U., Safer A., Rahlfs V.W. Durch Prämedikation, Narkose und Operation bedingte Änderungen des Gerinnungs- und Fibrinolysesystems und der Thrombozyten Einfluβ von Dextran und Hydroxyäthylstärke (HÄS) während und nach operation. Anaesthesist. 26:1977;77-84.
40. Scherer R., Giebler R., Kampe S., Kox W.J. Effects of hypertonic saline hydroxyethyl starch solution on collagen-induced platelet aggregation and ATP secretion. Infusionsther Transfusionsmed. 21:1994;310-314.
41. Harbury C.B., Schrier S.L. The effect of a partial release reaction on subsequent platelet function. J Lab Clin Med. 83:1974;877-886.
42. Aursnes I., Stenberg Nielsen H. Low dose infusion of adenosine diphosphate prolongs bleeding time in rats and rabbits. Thromb Res. 68:1992;67-74.