Cerebral glucose utilization and glucose transporter expression: Response to water deprivation and restoration

Journal of Cerebral Blood Flow and Metabolism

Volumn 20, Issue 1, 2000, Pages 192-200

  Koehler Stec, Ellen M ^a   Li, Kang ^a   Maher, Fran ^a   Vannucci, Susan J ^b   Smith, Carolyn B ^c   Simpson, Ian A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Deoxyglucose; Energy metabolism; Glucose transport; GLUT1; GLUT3; Hypothalamoneurohypophysial system

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; M PROTEIN; MESSENGER RNA; WATER;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WATER DEPRIVATION;

EID: 0033962167     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200001000-00024     Document Type: Article

References (28)

1. Boado RJ, Pardridge WM (1993) Glucose deprivation causes posttranscriptional enhancement of brain capillary endothelial glucose transporter gene expression via GLUT1 mRNA stabilization. J Neurochem 60:2290-2296
2. Bondy CA, Lee W-H, Zhou J (1992) Ontogeny and cellular distribution of brain glucose transporter gene expression. Mol Cell Neurosci 3:305-314
3. Droz B, Lebond CP (1963) Axonal migration of proteins in the central nervous system and peripheral nerves as shown by radioautography. J Comp Neural 121:325-346
4. Dwyer KJ, Boado RJ, Pardridge WM (1996) Cis-element/cytoplasmic protein interaction within the 3′-untranslated region of the GLUT1 glucose transporter mRNA. J Neurochem 66:449-158
5. Dyball REJ, Leng G (1989) Hypothalamic microcircuits involved in osmoregulation. Biomed Res 10:21-32
6. Gainer H, Wray S (1994) Cellular and molecular biology of oxytocin and vasopressin. In: The Physiology of Reproduction (Knobil E, Neill JD, eds). 2nd ed. New York, Raven Press, Vol. 2, pp 1099-1129
7. Grafstein B, Foreman DS (1980) Intracellular transport in neurons. Physhl Rev 60(4): 1167-1283
8. Hatton GI (1988) Pituicytes, glia and control of terminal secretion. J Exp Biol 139:67-79
9. Hatton GI (1990) Emerging concepts of structure-function dynamics in adult brain: the hypothalamo-neurohypophysial system. Prog Neurobiol 34:437-504
10. Jirikowski GF, Sanna PP, Bloom FE (1990) mRNA coding for oxytocin in present in axons of the hypothalamo-neurohypophysial tract. Proc NAll Acad Sci USA 87:7400-7404
11. Kadekaro M, Gross PM, Sokoloff L, Holcomb HH, Saavedra JM (1983) Elevated glucose utilization in subfornical organ and pituitary neural lobe of the Brattleboro rat. Brain Res 275:189-193
12. Kadekaro M, Summy-Long JY, Freeman S, Harris JS, Terrell ML, Eisenberg HM (19,92) Cerebral metabolic responses and vasopressin and oxytocin secretions during progressive water deprivation in rats. Am J Physiol 262:R310-R317
13. Khayat ZA, McCall AL, Klip A (1998) Unique mechanism of GLUTS transporter regulation by prolonged energy demand: increased protein half-life. Biochem J 333:713-718
14. Klein B, Kuschinsky W, Schrock H, Viard I (1986) Interdependency of local capillary density, blood flow, and metabolism in rat brains. Am J Physiol 251:HI333-HI340
15. Klip A, Tsakiridis T, Marette A, Ortiz PA (1994) Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures. FASEB J 8:43-53
16. Lawson LJ, Perry VH, Gordon S (1993) Microglial responses to physiological change: osmotic stress elevates DNA synthesis of neurohypophyseal microglia. Neuroscience 56(4):929-938
17. Lee W-H, Bondy CA (1993) Ischemic injury induces brain glucose transporter gene expression. Endocrinology 133:2540-2544
18. Li K, Vannucci SJ, Maher F, Barone FC, Lysko PG, Simpson IA (1996) GLUTS microglial response in adult and immature rat brain following stroke [abstract]. Soc Neurosci 22:1423
19. Maher F, Davies-Hill TM, Lysko PG, Henneberry RC, Simpson IA (1991) Expression of two glucose transporters, GLUT1 and GLUT3 in cultured cerebellar neurons: evidence for neuronspecific expression of GLUT3. Mol Cell Neurosci 2:351-360
20. Maher F, Vannucci S, Takeda J, Simpson IA (1992) Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain. Biochem Biophys Res Commun 182(2):703-711
21. Maher F, Vannucci SJ, Simpson IA (1994) Glucose transporter proteins in brain. FASEB J 8:1003-1011
22. Mander TH, Morris JF (1994) Perivascular microglia in the rat neural lobe engulf magnocellular secretory terminals during osmotic stimulation. Neurosci Lett 180:235-238
23. McGowan KM, Long SD, Pekala PH (1995) Glucose transporter gene expression: regulation of transcription and mRNA stability. Pharmacol Ther 66(3):465-505
24. McKinley MJ, Denton DA, Rundgren M, Weisinger RS (1987) Osmoreception. In: Circumventricular Organs and Body Fluids (Gross PM, ed), Boca Raton, FL, CRC Press, Vol. 3, pp 85-103
25. Mohr E, Fehr S, Richter D (1991) Axonal transport of neuropeptideencoding mRNAs within the hypothalamo-hypophyseal tract of rats. EMBO J 10:2419-2424
26. Paxinos G, Watson C (1986) The Rat Brain in Stereotaxic Coordinates. 2nd ed. San Diego, CA, Academic Press
27. Payne J, Mattiaci LA, Maher F, Simpson IA, Davies P (1993) Expression of GLUTS on microglia in normal and AD brain [abstract]. Soc Neurosci 19:1042
28. Rahner-Welsch S, Vogel J, Kuschinsky W (1995) Regional congruence and divergence of glucose transporters (GLUT1) and capillaries in rat brains. J Cereb Blood Flow Metab 15:681-686