L-Glutamate suppresses amyloid β-protein-induced stellation of cultured rat cortical astrocytes

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 280-286

  Abe, Kazuho ^a   Saito, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Amyloid protein; Astrocyte; Culture; Glutamate; Stellation

Indexed keywords

AMYLOID BETA PROTEIN; ASPARTIC ACID; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; PROTEIN SUBUNIT;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRUCTURE; CELL VIABILITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STELLATE CELL;

AMYLOID BETA-PROTEIN; ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE;

ANIMALIA;

EID: 0033961790     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740280.x     Document Type: Article

References (42)

1. 2+ concentration in rat hippocampal neurons. Brain Res. 587, 102-108.
2. Abe K. and Saito H. (1996) Menadione toxicity in cultured rat cortical astrocytes. Jpn. J. Pharmacol. 72, 299-306.
3. Abe K. and Saito H. (1997) Developmental changes in cyclic AMP-stimulated stellation of cultured rat cortical astrocytes. Jpn. J. Pharmacol 75, 433-438.
4. Abe K. and Saito H. (1998) Adenosine stimulates stellation of cultured rat cortical astrocytes. Brain Res. 804, 63-71.
5. 2-adrenoceptor-mediated contractions of rat tail artery. Eur. J. Pharmacol. 171, 59-67.
6. Abe K., Kato M., and Saito H. (1997) Human amylin mimics amyloid β protein-induced reactive gliosis and inhibition of cellular redox activity in cultured astrocytes. Brain Res. 762, 285-288.
7. Amato A., Ballerini L., and Attwell D. (1994) Intracellular pH changes produced by glutamate uptake in rat hippocampal slices. J. Neurophysiol. 72, 1686-1696.
8. Arriza J. L., Fairman W. A., Wadiche J. I., Murdoch G. H., Kavanaugh M. P., and Amara S. G. (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J. Neurosci. 14, 5559-5569.
9. Arriza J. L., Eliasof S., Kavanaugh M. P., and Amara S. G. (1997) Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc. Natl. Acad. Sci. USA 94, 4155-4160.
10. Bales K. R., Du Y., Dodel R. C., Yan G. M., Hamilton-Byrd E., and Paul S. M. (1998) The NF-κB/Rel family of proteins mediates Aβ-induced neurotoxicity and glial activation. Mol. Brain Res. 57, 63-72.
11. Behl C., Davis J. B., Lesley R., and Schubert D. (1994) Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77, 817-827.
12. Canning D. R., McKeon R. J., DeWitt D. A., Perry G., Wujek J. R., Frederickson R. C. A., and Silver J. (1993) β-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal growth. Exp. Neurol. 124, 289-298.
13. Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
14. Davis-Cox M. I., Turner J. N., Szarowski D., and Shain W. (1994) Phorbol ester-stimulated stellation in primary cultures of astrocytes from different brain regions. Microsc. Res. Tech. 29, 319-327.
15. Dickson D. W., Farlo J., Davies P., Crystal H., Fuld P., and Yen S. C. (1988) A double-labeling immunohistochemical study of senile plaques. Am. J. Pathol. 132, 86-101.
16. Duffy P. E., Rapport M., and Graf L. (1980) Glial fibrillary acidic protein and Alzheimer-type senile dementia. Neurology 30, 778-782.
17. Fairman W. A., Vandenberg R. J., Arriza J. L., Kavanaugh M. P., and Amara S. G. (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375, 599-603.
18. Flott B. and Seifert W. (1991) Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain. Glia 4, 293-304.
19. +-dependent glutamate uptake in rat hippocampal astrocyte cultures. J. Neurochem. 67, 277-286.
20. Hu J., Akama K. T., Krafft G. A., Chromy B. A., and Van Eldik L. J. (1998) Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release. Brain Res. 785, 195-206.
21. Kanai Y. and Hediger M. A. (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360, 467-471.
22. Kanner B. I. (1993) Glutamate transporters from brain: a novel neurotransmitter transporter family. FEBS Lett. 325, 95-99.
23. Kato M., Saito H., and Abe K. (1997) Nanomolar amyloid β protein-induced inhibition of cellular redox activity in cultured astrocytes. J. Neurochem. 68, 1889-1895.
24. Koh J. Y., Yang L. L., and Cotman C. W. (1990) β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533, 315-320.
25. Mandybur T. I. and Chuirazzi C. C. (1990) Astrocytes and the plaques of Alzheimer's disease. Neurology 40, 635-639.
26. Mattson M. P., Cheng B., Davis D., Bryant K., Lieberburg I., and Rydel R. E. (1992) β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12, 376-389.
27. Mattson M. P., Tomaselli K. J., and Rydel R. E. (1993) Calcium-destabilization and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF. Brain Res. 621, 35-49.
28. Mobley P. L., Scott S. L., and Cruz E. G. (1986) Protein kinase C in astrocytes: a determinant of cell morphology. Brain Res. 398, 366-369.
29. Moonen G., Cam Y., Sensenbrenner M., and Mandel P. (1976) Variability of the effects of serum-free medium, dibutyryl cyclic AMP, or theophylline on the morphology of cultured newborn rat astrocytes. Cell Tissue Res. 163, 365-372.
30. Parpura-Gill A., Beitz D., and Uemura E. (1997) The inhibitory effects of β-amyloid on glutamate and glucose uptakes by cultured astrocytes. Brain Res. 754, 65-71.
31. Patel A. J., Gunasekera S., Jen A., and Rohan de Silva H. A. (1996) β-Amyloid-mediated inhibition of redox activity (MTT reduction) is not an indicator of astroglial degeneration. Neuroreport 7, 2026-2030.
32. Pike C. J., Walencewicz A. J., Glabe C. G., and Cotman C. W. (1991) In vivo aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563, 311-314.
33. Pike C. J., Cummings B. J., Monzavi R., and Cotman C. W. (1994) β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience 63, 517-531.
34. Pines G., Danbolt N. C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J., Seeberg E., and Kanner B. I. (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature 360, 464-467.
35. Rothman S. M. and Olney J. W. (1986) Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol 19, 105-111.
36. Sarantis M., Ballerini L., Miller B., Silver R. A., Edwards M., and Attwell D. (1993) Glutamate uptake from the synaptic cleft does not shape the decay of the non-NMDA component of the synaptic current. Neuron 11, 541-549.
37. +-dependent glutamate transporters by cyclic AMP analogs and neurons. Mol. Pharmacol. 53, 355-369.
38. Schwarcz R., Foster A. C., French E. D., Whetsell W. O., and Kohler C. (1984) Excitotoxic models for neurodegenerative disorders. Life Sci. 35, 19-32.
39. +-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA 89, 10955-10959.
40. Swanson R. A., Liu J., Miller J. W., Rothstein J. D., Farrel K., Stein B. A., and Longuemare M. C. (1997) Neuronal regulation of glutamate transporter subtype expression in astrocytes. J. Neurosci. 17, 932-940.
41. Tanaka K. (1993) Expression cloning of a rat glutamate transporter. Neurosci. Res. 16, 149-153.
42. Yankner B. A., Duffy L. K., and Kirschner D. A. (1990) Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 25, 279-282.