Fetal 'space-suit' hydrops in the first trimester: Differentiating risk for chromosome abnormalities by delineating characteristics of nuchal translucency

Prenatal Diagnosis

Volumn 20, Issue 1, 2000, Pages 30-32

  Shulman, Lee P ^a,b   Phillips, Owen P ^a   Emerson, Donald S ^a   Felker, Richard E ^a   Tharapel, Avirachan T ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Chromosome abnormalities; First trimester; Nuchal translucency; Prenatal diagnosis; Ultrasound

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; AUTOSOME ABERRATION; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CYTOGENETICS; FEMALE; FETUS ECHOGRAPHY; FETUS HYDROPS; FETUS KARYOTYPING; FIRST TRIMESTER PREGNANCY; GENETIC COUNSELING; GESTATIONAL AGE; HUMAN; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SEX CHROMOSOME; TRANSVAGINAL ECHOGRAPHY;

HYDROPS;

EID: 0033960266     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(200001)20:1<30::AID-PD750>3.0.CO;2-9     Document Type: Article

References (14)

1. Bernstein HS, Filly RA, Goldberg JD. Golbus MS. 1991. Prognosis of fetuses with a cystic hygroma. Prenat Diagn 11: 349-355.
2. Brady AF, Pandya PP, Yuksel B, Greenough A, Patton MA, Nicolaides KH. 1998. Outcome of chromosomally normal livebirths with increased fetal nuchal translucency at 10-14 weeks' gestation. J Med Genet 35: 222-224.
3. Bronshtein M, Bar-Hava I, Blumenfeld I, Bejar J, Toder A, Blumenfeld Z. 1993. The difference between septated and nonseptated nuchal cystic hygroma in the early second trimester. Obstet Gynecol 81: 683-687.
4. Hyett J, Perdu M, Sharland G, Snijders R, Nicolaides KH. 1999. Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14 weeks of gestation: population based cohort study. BMJ 318: 81-85.
5. Lazanakis MS, Rodgers K, Economides DL. 1998. Increased nuchal translucency and CATCH 22. Prenat Diagn 18: 507-510.
6. Nicolaides KH, Azar G, Byrne D, Mansur C, Marks K. 1992. Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy. Br Med J 304: 867-869.
7. Pandya PP, Snijders RJM, Johnson SJ, Brizot M, Nicolaides KH. 1995. Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10 to 14 weeks of gestation. Br J Obstet Gynaecol 102: 957-962.
8. Sebire NJ, Snijders RJ, Brown R, Southall T, Nicolaides KH. 1998. Detection of sex chromosome abnormalities by nuchal translucency screening at 10-14 weeks. Prenat Diagn 18: 581-584.
9. Shulman LP, Emerson DS, Felker RE, Phillips OP, Simpson JL, Elias S. 1992. High frequency of cytogenetic abnormalities in fetuses with cystic hygroma diagnosed in the first trimester. Obstet Gynecol 80: 80-82.
10. Shulman LP, Emerson DS, Grevengood C, Felker RE, Gross SJ, Phillips OP, Elias S. 1994a. Clinical course and outcome of fetuses with isolated cystic nuchal lesions and normal karyotypes detected in the first trimester. Am J Obstet Gynecol 171: 1278-1281.
11. Shulman LP, Raafat NA, Mace PC, Emerson DS, Felker RE, Simpson JL. Elias S. 1994b. Significance of septations in isolated fetal cystic hygroma detected in the first trimester. Prenat Diagn 14: 223-226.
12. Snijders RJM, Johnson S, Sebire NJ, Noble PL, Nicolaides KH. 1996. First-trimester ultrasound screening for chromosomal defects. Ultrasound Obstet Gynecoll: 216-226.
13. Van Vugt JMG, Tinnemans BW, van Zalen-Sprock RM. 1998. Outcome and early childhood follow-up of chromosomally normal fetuses with increased nuchal translucency at 10-14 weeks' gestation. Ultrasound Obstet Gynecol 11: 407-409.
14. Van Zalen-Sprock RM, Van Vugt JMG, Van Geijn HP. 1993. First-trimester diagnosis of cystic hygroma-course and outcome. Am J Obstet Gynecol 167: 94-98.