The skin permeation mechanism of ketotifen: Evaluation of permeation pathways and barrier components in the stratum corneum

Drug Development and Industrial Pharmacy

Volumn 26, Issue 1, 2000, Pages 45-53

  Inoue, Kazuhiro ^a   Ogawa, Kengo ^a   Suzuki, Yukie ^a   Okada, Junichi ^a   Kusai, Akira ^a   Ikeda, Masaru ^a   Nishimura, Kenji ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Delipidization; Ketotifen; Lipid; Partition coefficient; Permeability coefficient; Protein; Stratum corneum; Uptake

Indexed keywords

KETOTIFEN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG PENETRATION; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PARTITION COEFFICIENT; SKIN PERMEABILITY; STRATUM CORNEUM;

ALGORITHMS; ANIMALS; ANTIPRURITICS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; KETOTIFEN; LIPIDS; MALE; MICE; MICE, INBRED HRS; PHARMACEUTICAL SOLUTIONS; SKIN; SKIN ABSORPTION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0033959507     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100100326     Document Type: Article

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