Isolation and characterization of vancomycin-tolerant Streptococcus pneumoniae from the cerebrospinal fluid of a patient who developed recrudescent meningitis

Journal of Infectious Diseases

Volumn 181, Issue 1, 2000, Pages 369-373

  McCullers, Jonathan A ^a,b   English, B Keith ^b,c   Novak, Rodger ^a,d  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b LE BONHEUR CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFOTAXIME; CEFTRIAXONE; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL MENINGITIS; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; FEMALE; HUMAN; INFANT; PRIORITY JOURNAL; STRAIN DIFFERENCE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

BACTERIOLYSIS; CEPHALOSPORINS; FEMALE; HEAD; HUMANS; INFANT; MAGNETIC RESONANCE IMAGING; MENINGITIS, PNEUMOCOCCAL; RECURRENCE; SPINE; TOMOGRAPHY; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 0033958626     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315216     Document Type: Article

References (12)

1. 1. Schuchat A, Robinson K, Wenger JD, et al. Bacterial meningitis in the United States in 1995. Active Surveillance Team. N Engl J Med 1997; 337:970-6.
2. 2. Kaplan SL, Mason EOJ, Barson WJ, et al. Three-year multicenter surveillance of systemic pneumococcal infections in children. Pediatrics 1998; 102:538-45.
3. 3. American Academy of Pediatrics Committee on Infectious Diseases. Therapy for children with invasive pneumococcal infections. Pediatrics 1997; 99: 289-99.
4. 4. Novak R, Henriques B, Charpentier E, Normark S, Tuomanen E. Emergence of vancomycin tolerance in Streptococcus pneumoniae. Nature 1999; 399: 590-3.
5. 5. Novak R, Charpentier E, Henriques B, Normark S, Tuomanen E. Vancomycin tolerance in Streptococcus pneumoniae: transport of a signal peptide regulated by a two component system [abstract 97-CC-145]. In: Proceedings of 38th Interscierice Conference of Antimicrobial Agents and Chemotherapy (San Diego) 1998.
6. 6. Tuomanen E, Pollack H, Parkinson A, et al. Microbiological and clinical significance of a new property of defective lysis in clinical strains of pneumococci. J Infect Dis 1988; 158:36-43.
7. 7. Liu HH, Tomasz A. Penicillin tolerance in multiply drug-resistant natural isolates of Streptococcus pneumoniae. J Infect Dis 1985; 152:365-72.
8. 8. Tomasz A, Albino A, Zanati E. Multiple antibiotic resistance in a bacterium with suppressed autolytic system. Nature 1970; 227:138-40.
9. 9. Lacks S, Hotchkiss RD. A study of the genetic material determining an enzyme activity in pneumococcus. Biochem Biophys Acta 1960; 39:508-17.
10. 10. Mosser JL, Tomasz A. Choline-containing teichoic acid as a structural component of pneumococcal cell wall and its role in sensitivity to lysis by an autolytic enzyme. J Biol Chem 1970; 245:287-98.
11. 11. Tomasz A, Beckerdite S, McDonnell M, Elsbach P. The activity of the pneumococcal autolytic system and the fate of the bacterium during ingestion by rabbit polymorphonuclear leukocytes. J Cell Physiol 1977; 92:155-60.
12. 12. Holtje JV, Tuomanen EI. The murein hydrolases of Escherichia coli: properties, functions and impact on the course of infections in vivo. J Gen Microbiol 1991; 137:441-54.