Multiepitope synthetic peptide and recombinant protein for the detection of antibodies to Trypanosoma cruzi in patients with treated or untreated Chagas' disease

Journal of Infectious Diseases

Volumn 181, Issue 1, 2000, Pages 325-330

  Houghton, Raymond L ^a   Benson, Darin R ^a   Reynolds, Lisa ^a   McNeill, Patricia ^a   Sleath, Paul ^a   Lodes, Michael ^a   Skeiky, Yasir A W ^a   Badaro, Roberto ^b   Krettli, Antoniana U ^c   Reed, Steven G ^a  

^a GLAXOSMITHKLINE   (United States)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY DETECTION; ARTICLE; CHAGAS DISEASE; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MAJOR CLINICAL STUDY; PARASITEMIA; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

ANTIBODIES, PROTOZOAN; BRAZIL; CHAGAS DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNODOMINANT EPITOPES; OLIGOPEPTIDES; PARASITEMIA; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0033958622     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315165     Document Type: Article

References (29)

1. 1. Tanowitz HB, Kirchhoff LV, Simon D, Morris SA, Weiss LM, Wittner M Chagas' disease. Clin Microbiol Rev 1992; 5:400-19.
2. 2. Kirchhoff LV. Trypanosoma species (American trypanosomiasis, Chagas' disease): biology of trypanosomes. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1997:2077.
3. 3. Schmunis GA. Trypanosoma cruzi, the etiologic agent of Chagas' disease: status in the blood supply in endemic and nonendemic countries. Transfusion 1991; 31:547-57.
4. 4. Wendel S, Gonzaga AL. Chagas' disease and blood transfusion: a New World problem? Vox Sang 1993; 64:1-12.
5. 5. Krieger MA, Almeida E, Oelemann W, et al. Use of recombinant antigens for the accurate immunodiagnosis of Chagas' disease. Am J Trop Med Hyg 1992; 46:427-34.
6. 6. Camargo ME. Fluorescent antibody test for the serodiagnosis of American trypanosomiasis; technical modification employing preserved culture forms of Trypanosoma cruzi in a slide test. Rev Inst Med Trop Sao Paulo 1966; 8:227-34.
7. 7. Schattschneider W, Lopes ER, De Alencar JE, Bienzle U, Feldmeier H. A comparative study of four serological methods for diagnosis of acute and Chronic Chagas' disease in Brazilian patients. Trop Geogr Med 1992; 44: 210-18.
8. 8. Hoshino-Shimizu S, Camargo ME, Nagasse TK. A stable polysaccharide hemagglutination reagent for diagnosis of acute or recent Trypanosoma cruzi infections. Rev Inst Med Trop Sao Paulo 1978; 20:208-12.
9. 9. Cuba CC, Alvarenga NJ, Barreto AC, Marsden PD, Macedo V, Gama MP. Dipetalogaster maximus (Hemiptera, Triatominae) for xenodiagnosis of patients with serologically detectable Trypanosoma cruzi infection. Trans R Soc Trop Med Hyg 1979; 73:524-27.
10. 10. Luz ZM, Coutinho MG, Cancado JR, Krettli AU. Hemocultura: tecnica sensivel na deteccao do Trypanosoma cruzi en pacientes chagasicos na fase cronica do doenca de Chagas. Rev Soc Bras Med Trop 1994; 27:143-48.
11. 11. Bestetti RB, Freitas OC, Muccillo G, Oliveira JS. Clinical and morphological characteristics associated with sudden cardiac death in patients with Chagas' disease. Eur Heart J 1993; 14:1610-14.
12. 12. Skeiky YA, Benson DR, Parsons M, Elkon KB, Reed SG. Cloning and expression of Trypanosoma cruzi ribosomal protein PO and epitope analysis of anti-PO autoantibodies in Chagas' disease patients. J Exp Med 1992; 176:201-11.
13. 13. Van Voorhis WC, Schlekewy L, Trong HL. Molecular mimicry by Trypanosoma cruzi: the F1-160 epitope that mimics mammalian nerve can be mapped to a 12-amino acid peptide. Proc Natl Acad Sci USA 1991; 88: 5993-97.
14. 14. Cotrim PC, Paranhos GS, Mortara RA, et al. Expression in Escherichia coli of a dominant immunogen of Trypanosoma cruzi recognized by human chagasic sera. J Clin Microbiol 1990; 28:519-24.
15. 15. Skeiky YA, Benson DR, Elwasila M, Badaro R, Burns JM, Reed SG. Antigens shared by Leishmania species and Trypanosoma cruzi: immunological comparison of the acidic ribosomal PO proteins. Infect Immun 1994; 62:1643-51.
16. 16. Ibanez CF, Affranchino JL, Macina RA, et al. Multiple Trypanosoma cruzi antigens containing tandemly repeated aminoacid sequence motifs. Mol Biochem Parasitol 1988; 30:27-34.
17. 17. Vergara U, Veloso C, Gonzalez A, Lorca M. Evaluation of an enzyme-linked immunosorbent assay for the diagnosis of Chagas' disease using synthetic peptides. Am J Trop Med Hyg 1992; 46:39-43.
18. 18. Hoft DF, Kim KS, Otsu K, et al. Trypanosama cruzi expresses diverse repetitive protein antigens. Infect Immun 1989; 57:1959-67.
19. 19. Burns JM, Shreffler WG, Rosman DR, Sleath PR, March CJ, Reed SG. Identification and synthesis of a major conserved antigenic epitope of Trypanosoma cruzi. Proc Natl Acad Sci USA 1992; 89:1239-43.
20. 20. Peralta JM, Teixeira MG, Shreffler WG, et al. Serodiagnosis of Chagas' disease by an enzyme-linked immunosorbent assay using two synthetic peptides as antigens. J Clin Microbiol 1994; 32:971-74.
21. 21. Houghton RL, Benson DR, Skeiky YA, et al. Multi-epitope peptide ELISA for the detection of serum antibodies to Trypanosama cruzi in patients with treated and untreated Chagas' disease. Transfusion 1996; 36(Suppl): S135.
22. 22. Houghton RL, Benson DR, Skeiky YA, et al. A multi-epitope ELISA for the detection of antibodies to Trypanosoma cruzi in RIPA confirmed and consensus positive sera. Transfusion 1996; 36(Suppl):S14.
23. 23. Honghton RL, Benson DR, Reynolds LD, et al. A multi-epitope synthetic peptide and recombinant protein for the detection of antibodies to Trypanosoma cruzi in radioimmunoprecipitation confirmed and consensus-positive sera. J Infect Dis 1999; 179:1226-34.
24. 24. Galvao LM, Nunes RM, Cancado JR, Brener Z, Krettli AU. Lytic antibody titer as a means of assessing cure after treatment of Chagas' disease: a 10 years follow up study, Trans R Soc Trop Med Hyg 1993; 87:220-23.
25. 25. Krautz GM, Galvao LM, Cancado JR, Guevara-Espinoza A, Ouaissi A, Krettli AU. Use of a 24 kilodalton Trypanosoma cruzi recombinant protein to monitor cure of human Chagas' disease. J Clin Microbiol 1995; 33: 2086-90.
26. 26. Western KA, Schultz MG, Farrar WE, Kagan I. Laboratory acquired Chagas' disease treated with Bay 2502. Bol Oficina Sanit Panam (Communicaciones). 1969; 67:94 (abstract).
27. 27. Kirchhoff LV, Gam AA, Gusmao RA, Goldsmith RS, Rezende JM, Rassi A. Increased specificity of serodiagnosis of Chagas' disease by detection of antibody to the 72-and 90 kilodalton glycoproteins of Trypanosoma cruzi. J Infect Dis 1987; 155:561-64.
28. 28. Brashear RJ, Winkler MA, Schur JD, et al. Detection of antibodies to Trypanosoma cruzi among blood donors in the southwestern and western United States I. Evaluation of the sensitivity of an enzyme immunoassay for detecting antibodies to T. cruzi, Transfusion 1995; 35:213-8.
29. 29. Winkler MA, Brashear RJ, Hall HJ, Schur JD, Pan AA. Detection of antibodies to Trypanosoma cruzi among blood donors in the southwestern and western United States, II: evaluation of a supplemental enzyme immunoassay and radioimmunoprecipitation assay for the confirmation of seroreactivity. Transfusion 1995; 35:219-25.