The induction of hepatic microsomal UDP-glucuronosyltransferase by the methylsulfonyl metabolites of polychlorinated biphenyl congeners in rats

Chemico-Biological Interactions

Volumn 125, Issue 2, 2000, Pages 107-115

  Kato, Yoshihisa ^a   Haraguchi, Koichi ^b   Shibahara, Tomoo ^a   Shinmura, Yasuhiko ^a   Masuda, Yoshito ^b   Kimura, Ryohei ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

Author keywords

Induction; Methylsulfonyl metabolite; Polychlorinated biphenyl; Rat; UDP glucuronosyltransferase

Indexed keywords

GLUCURONOSYLTRANSFERASE; POLYCHLORINATED BIPHENYL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; LIVER METABOLISM; MALE; RAT; XENOBIOTIC METABOLISM;

ANIMALS; ENZYME INDUCTION; GLUCURONOSYLTRANSFERASE; MALE; METHYLATION; MICROSOMES, LIVER; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; SULFONES; THYROXINE;

EID: 0033956499     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(99)00168-4     Document Type: Article

References (35)

1. De Voogt P., Wells D.E., Reutergårdh L., Brinkman U.A.Th. Biological activity, determination and occurrence of planar, mono- and di-ortho PCBs. Int. J. Anal. Chem. 40:1990;1-46.
2. Safe S. Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems. Environ. Health Perspect. 100:1992;259-268.
3. Olafsson P.G., Bryan A.M., Stone W. PCB congener-specific analysis: a critical evaluation of toxic levels in biota. Chemosphere. 16:1987;2585-2593.
4. Kannan N., Tanabe S., Ono M., Tatsukawa R. Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean. Arch. Environ. Contam. Toxicol. 18:1989;850-857.
5. Safe S., Safe L., Mullin M. Polychlorinated biphenyls: congener-specific analysis of a commercial mixture and a human milk extract. J. Agric. Food Chem. 33:1985;24-29.
6. Dewailly É., Weber J.-P., Gingras S., Laliberté C. Coplanar PCBs in human milk in the province of Québec, Canada: are they more toxic than dioxin for breast fed infants? Bull. Environ. Contam. Toxicol. 47:1991;491-498.
7. Haraguchi K., Athanasiadou M., Bergman Å., Hovander L., Jensen S. PCB and PCB methyl sulfones in selected groups of seals from Swedish waters. Ambio. 21:1992;546-549.
8. Bergman Å., Athanasiadou M., Bergek S., Haraguchi K., Jensen S., Klasson-Wehler E. PCB and PCB methyl sulfones in mink treated with PCB and various PCB fractions. Ambio. 21:1992;570-576.
9. Bergman Å., Norstrom R.J., Haraguchi K., Kuroki H., Béland P. PCB and DDE methyl sulfones in mammals from Canada and Sweden. Environ. Toxicol. Chem. 13:1994;121-128.
10. Letcher R.J., Norstrom R.J., Bergman Å. Geographical distribution and identification of methyl sulphone PCB and DDE metabolites in pooled polar bear (Ursus maritimus) adipose tissue from western hemisphere Arctic and Subarctic regions. Sci. Total Environ. 160/161:1995;409-420.
11. Haraguchi K., Kuroki H., Masuda Y. Capillary gas chromatographic analysis of methylsulphone metabolites of polychlorinated biphenyls retained in human tissues. J. Chromatogr. 361:1986;239-252.
12. Haraguchi K., Kuroki H., Masuda Y. Polychlorinated biphenyl methylsulfone congeners in human tissues: identification of methylsulfonyl dichlorobiphenyls. Chemosphere. 18:1989;477-484.
13. Norén K., Lundén Å., Pettersson E., Bergman Å. Methylsulfonyl metabolites of PCBs and DDE in human milk in Sweden, 1972-1992. Environ. Health Perspect. 104:1996;766-772.
14. Weistrand C., Norén K. Methylsulfonyl metabolites of PCBs and DDE in human tissues. Environ. Health Perspect. 105:1997;644-649.
15. Weistrand C., Norén K., Nilsson A. Organochlorine compounds in blood plasma from potentially exposed workers: PCB, PCN, PCDD/PCDF, HCB and methylsulphonyl metabolites of PCB. Environ. Sci. Pollut. Res. 4:1997;2-9.
16. Kato Y., Haraguchi K., Kawashima M., Yamada S., Masuda Y., Kimura R. Induction of hepatic microsomal drug metabolizing enzymes by methylsulphonyl metabolites of polychlorinated biphenyl congeners in rats. Chem.-Biol. Interact. 95:1995;257-268.
17. Kato Y., Haraguchi K., Kawashima M., Yamada S., Isogai M., Masuda Y., Kimura R. Characterization of hepatic microsomal cytochrome P-450 from rats treated with methylsulphonyl metabolites of polychlorinated biphenyl congeners. Chem.-Biol. Interact. 95:1995;269-278.
18. Kato Y., Haraguchi K., Tomiyasu K., Saito H., Isogai M., Masuda Y., Kimura R. Structure-dependent induction of CYP2B1/2 by 3-methylsulfonyl metabolites of polychlorinated biphenyl congeners in rats. Environ. Toxicol. Pharmacol. 3:1997;137-144.
19. Y. Kato, K. Haraguchi, K. Tomiyasu, H. Saito, T. Shibahara, Y. Masuda, R. Kimura, The role of 3-methylsulfonyl-2,2′,4′,5,5′-pentachlorobiphenyl, a metabolite of 2,2′,4,5,5′-pentachlorobiphenyl, in the induction of hepatic microsomal drug-metabolizing enzymes by 2,2′,4,5,5′-pentachlorobiphenyl in rats. Environ. Toxicol. Pharmacol. 8 (1999) 39-47.
20. Kato Y., Haraguchi K., Shibahara T., Masuda Y., Kimura R. Reduction of thyroid hormone levels by methylsulfonyl metabolites of polychlorinated biphenyl congeners in rats. Arch. Toxicol. 72:1998;541-544.
21. Kato Y., Haraguchi K., Shibahara T., Yumoto S., Masuda Y., Kimura R. Reduction of thyroid hormone levels by methylsulfonyl metabolites of tetra- and pentachlorinated biphenyls in male Sprague-Dawley rats. Toxicol. Sci. 48:1999;51-54.
22. Y. Kato, K. Haraguchi, T. Shibahara, S. Yumoto, Y. Masuda, R. Kimura, Reduction of serum thyroxine concentrations by methylsulfonyl metabolites of tetra-, penta- and hexachlorinated biphenyls in male Sprague-Dawley rats. Chemosphere 40 (2000) 1233-1240.
23. Carlson G.P. Induction of cytochrome P-450 by halogenated benzenes. Biochem. Pharmacol. 27:1978;361-363.
24. Bock K., Fröhling W., Remmer H., Rexer B. Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. Biochim. Biophys. Acta. 327:1973;46-56.
25. Haraguchi K., Kuroki H., Masuda Y. Synthesis and characterization of tissue-retainable methylsulfonyl polychlorinated biphenyl isomers. J. Agric. Food Chem. 35:1987;178-182.
26. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
27. Isselbacher K.J., Chrabas M.F., Quinn R.C. The solubilization and partial purification of a glucuronyl transferase from rabbit liver microsomes. J. Biol. Chem. 237:1962;3033-3036.
28. Winsnes A. Studies on the activation in vitro of glucuronyltransferase. Biochim. Biophys. Acta. 191:1969;279-291.
29. Ishii Y., Tsuruda K., Tanaka M., Oguri K. Purification of a phenobarbital-inducible morphine UDP-glucuronyltransferase isoform, absent from Gunn rat liver. Arch. Biochem. Biophys. 315:1994;345-351.
30. Barter R.A., Klaassen C.D. Rat liver microsomal UDP-glucuronosyltransferase activity toward thyroxine: characterization, induction, and form specificity. Toxicol. Appl. Pharmacol. 115:1992;261-267.
31. Mackenzie P.I., Owens I.S., Burchell B., Bock K.W., Bairoch A., Belanger A. et al. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics. 7:1997;255-269.
32. Barter R.A., Klaassen C.D. Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicol. Appl. Pharmacol. 128:1994;9-17.
33. Van Birgelen A.P.J.M., Smit E.A., Kampen I.M., Groeneveld C.N., Fase K.M., Van der Kolk J. et al. Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment. Eur. J. Pharmacol. 293:1995;77-85.
34. Schuur A.G., Boekhorst F.M., Brouwer A., Visser T.J. Extrathyroidal effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone turnover in male Sprague-Dawley rats. Endocrinology. 138:1997;3727-3734.
35. Visser T.J. Pathways of thyroid hormone metabolism. Acta Med. Austriaca Heft. 1/2:1996;10-16.