Characterisation of a 5-HT7 binding site in mouse ileum

European Journal of Pharmacology

Volumn 387, Issue 3, 2000, Pages 265-272

  Hemedah, Maggie ^a   Coupar, Ian M ^a   Mitchelson, Fred J ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

5 HT7 receptor; 3H Mesulergine; Ileum, mouse

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 5 CARBAMOYLTRYPTAMINE; LYSERGIDE; MESSENGER RNA; MESULERGINE; METERGOLINE; PINDOLOL; RISPERIDONE; RITANSERIN; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING SITE; FEMALE; ILEUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BINDING SITES; ERGOLINES; FEMALE; ILEUM; MALE; MICE; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 0033955424     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00797-9     Document Type: Article

References (43)

1. Aronstam R.S., Narayanan T.K. Temperature effect on the detection of muscarinic receptor-G protein interactions in ligand binding assays. Biochem. Pharmacol. 37:1988;1045-1049.
2. 7) positively linked to adenylate cyclase. J. Biol. Chem. 31:1993;23422-23426.
3. Boess F.G., Martin I.L. Molecular biology of 5-HT receptors. Neuropharmacology. 33:1994;275-317.
4. 3H]-RS-42358-197: evidence for receptor heterogeneity. J. Neurochem. 61:1993;1927-1932.
5. 2C receptor antagonist. Neuropharmacology. 36:1997;621-629.
6. Bradford M.M. A rapid sensitive method for quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
7. Carter D., Champney M., Hwang B., Eglen R.M. Characterization of post-junctional 5-hydroxytryptamine (5-HT) receptor mediating relaxation of guinea pig isolated ileum. Eur. J. Pharmacol. 280:1995;243-250.
8. Castro E.M., RomòN T., Castillo M.J., Del Olmo E., Pazos A., De Arco C. Identification and characterisation of a new serotonergic recognition site with high affinity for 5-carboxamidotryptamine in mammalian brain. J. Neuropharmacol. 69:1997;2123-2131.
9. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:1973;3099-3108.
10. 3H]Mesulergine, a selective ligand for serotonin-2 receptors. Life Sci. 32:1983;2485-2495.
11. Cushing D.J., Cohen M.L. Sertonin-induced relaxation in canine coronary artery smooth muscle. J. Pharmacol. Exp. Ther. 263:1992;123-129.
12. Dyer S.M., Bexis S., Mane M.T., De La Lande I.S., Frewin D.B., Head R.J. Interactions between 5-hydroxytryptamine, noradrenaline and the thromboxane-A(2) mimetic U44069 in the marmoset isolated aorta. Clin. Exp. Pharmacol. Physiol. 21:1994;201-206.
13. 7 receptor. Expert Opin. Invest. Drugs. 3:1994;175-177.
14. 7 receptor: orphan found. Trends Pharmacol. Sci. 18:1997;104-107.
15. Erlander M.G., Lovenberg T.W., Baron B.M., Delecea L., Danielson P.E., Racke M., Slone A.L., Siegel B.W., Foye P.E., Cannon K., Bruns J.E., Sutcliffe J.G. Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc. Natl. Acad. Sci. U.S.A. 90:1993;3452-3457.
16. Feniuk W., Humphrey P.P.A., Watts A.D. 5-Hydroxytryptamine-induced relaxation of isolated mammalian smooth muscle. Eur. J. Pharmacol. 96:1984;71-78.
17. 7 receptor in rat brain. Br. J. Pharmacol. 117:1996;657-666.
18. 7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organisation. J. Neurochem. 68:1997;1372-1381.
19. 7 sites in rat brain and guinea pig ileum but not rat jejunum. Br. J. Pharmacol. 126:1999;179-188.
20. Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Martin G.R., Mylecharane E.J., Saxena P.R., Humphrey P.P.A. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46:1994;157-204.
21. 125I]LSD binding. Eur. J. Pharmacol. 129:1986;139-145.
22. Kenakin T. The classification of drugs and drug receptors in isolated tissues. Pharmacol. Rev. 36:1984;165-222.
23. 7 receptors in inhibition of porcine myometrial contractility by 5-hydroxytryptamine. Br. J. Pharmacol. 123:1998;173-182.
24. 7) implicated in the regulation of mammalian circadian rhythms. Neuron. 11:1993;449-458.
25. 3 receptor mediating contraction of rat isolated jejunum. Eur. J. Pharmacol. 312:1996;215-225.
26. Monsma F.J. Jr., Shen Y., Ward R.P., Hamblin M.W., Sibley D.R. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol. Pharmacol. 43:1993;320-327.
27. Pazos A., Hoyer D., Palacios J.M. Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors. Eur. J. Pharmacol. 106:1985;531-538.
28. Plassat J.L., Amlaiky N., Hen R. Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol. Pharmacol. 44:1993;229-236.
29. Rinne U.K. New ergot derivatives in the treatment of Parkinson's disease. Calne D.B.et al. Lisuride and other dopamine agonists. 1983;431-442 Raven Press, New York.
30. Roth B.L., Craigo S.C., Choudhary M.S., Uluer A., Monsma F.J., Shen Y., Meltzer H.Y., Sibley D.R. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 268:1994;1403-1410.
31. 7) activating cyclic AMP formation. Proc. Natl. Acad. Sci. U.S.A. 90:1993;8547-8551.
32. Sanger G.J. 5-Hydroxytryptamine and functional bowel disorders. Neurogastroenterol. Motil. 8:1996;319-331.
33. 1-like receptors: a time to bid goodbye. Trends Pharmacol. Sci. 19:1998;311-316.
34. 7 serotonin receptor subtype. J. Biol. Chem. 268:1993;18200-18204.
35. Shenker A., Maayani S., Weinstein H., Green J.P. Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes. Mol. Pharmacol. 31:1987;357-367.
36. 7 receptor binding sites in rat hypothalamus: sensitivity of chronic antidepressant treatment. Mol. Pharmacol. 47:1995a;99-103.
37. 7 serotonin receptors: molecular biology and pharmacology. Neurotransmissions. 11:1995b;1-5.
38. Sumner M.J., Feniuk W., Humphrey P.P.A. Further characterisation of the 5-HT receptor mediating vascular relaxation and elevation of cyclic AMP in porcine isolated vena cava. Br. J. Pharmacol. 97:1989;292-300.
39. 2 receptors is not sensitive to GTP analogs. Mol. Pharmacol. 43:1993;915-920.
40. 7 receptors in guinea pig brain. Br. J. Pharmacol. 115:1995;107-116.
41. 7 receptor positively coupled to adenylyl cyclase. J. Neurochem. 63:1994;456-464.
42. 2-dopamine receptor in calf brain. Mol. Pharmacol. 25:1983;10-17.
43. Zifa E., Fillion G. 5-Hydroxytryptamine receptors. Pharmacol. Rev. 44:1992;401-458.