Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 278, Issue 1 41-1, 2000, Pages

  Ballatori, Nazzareno ^a,g   Rebbeor, James F ^a   Connolly, Gregory C ^a   Seward, David J ^b   Lenth, Benjamin E ^c   Henson, John H ^d   Sundaram, Pazhani ^e,f   Boyer, James L ^e,f  

^a UNIVERSITY OF ROCHESTER   (United States)

^b WILLIAMS COLLEGE   (United States)

^c WESLEYAN UNIVERSITY   (United States)

^d DICKINSON COLLEGE   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f MOUNT DESERT ISLAND BIOLOGICAL LABORATORY   (United States)

^g UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

ATP dependent; Bile salt transport; Membrane vesicles

Indexed keywords

BILE SALT; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PROTEIN BSEP; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BILE FLOW; CONTROLLED STUDY; ELECTRIC FISH; GENE CASSETTE; IMMUNOFLUORESCENCE; LIVER METABOLISM; MALE; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TRANSPORT KINETICS;

EID: 0033955249     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.278.1.g57     Document Type: Article

References (28)

1. Adachi, Y., H. Kobayashi, Y. Kurumi, M. Shouji, M. Kitano, and T. Yamamoto. ATP-dependent taurocholate transport by rat liver canalicular membrane vesicles. Hepatology 14: 655-659, 1991.
2. Ballatori, N., R. H. Moseley, and J. L. Boyer. Sodium gradient-dependent L-glutamate transport is localized to the canalicular domain of liver plasma membranes. J. Biol. Chem. 261: 6216-6221, 1986.
3. Ballatori, N., and A. T. Truong. Multiple canalicular transport mechanisms for glutathione S-conjugates: transport on both ATP- and voltage-dependent carriers. J. Biol. Chem. 270: 3594-3601, 1995.
4. Boyer, J. L., J. Schwarz, and N. Smith. Biliary secretion in elasmobranchs. II. Hepatic uptake and biliary excretion of organic anions. Am. J. Physiol. 230: 974-981, 1976.
5. Childs, S., R. L. Yeh, E. Georges, and V. Ling. Identification of a sister gene to P-glycoprotein. Cancer Res. 55: 2029-2034, 1995.
6. Childs, S., R. L. Yeh, D. Hui, and V. Ling. Taxol resistance mediated by transfection of the liver-specific sister of P-glycoprotein. Cancer Res. 58: 4160-4167, 1998.
7. Fricker, G., R. Wossner, J. Drewe, R. Fricker, and J. L. Boyer. Enterohepatic circulation of scymnol sulfate in an elasmobranch, the little skate (Raja erinacea). Am. J. Physiol. Gastrointest. Liver Physiol. 273: G1023-G1030, 1997.
8. Gerloff, T., B. Stieger, B. Hagenbuch, J. Madon, L. Landmann, J. Roth, A. F. Hofmann, and P. J. Meier. The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J. Biol. Chem. 273: 10046-10050, 1998.
9. Jacquemin, E., B. Hagenbuch, A. W. Wolkoff, P. J. Meier, and J. L. Boyer. Expression of sodium-independent organic anion uptake systems of skate liver in Xenopus laevis oocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 268: G18-G23, 1995.
10. Karlaganis, G., S. E. Bradley, J. L. Boyer, A. K. Batta, G. Salen, B. Egestad, and J. Sjovall. A bile alcohol sulfate as a major component in the bile of the small skate (Raja erinacea). J. Lipid Res. 30: 317-322, 1989.
11. Meier, P. J., U. Eckhardt, A. Schroeder, B. Hagenbuch, and B. Stieger. Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver. Hepatology 26: 1667-1677, 1997.
12. Meier, P. J., E. S. Sztul, A. Reuben, and J. L. Boyer. Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J. Cell Biol. 98: 991-1000, 1984.
13. Miller, D. S., G. Fricker, J. H. Henson, D. N. Hager, S. Nundy, N. Ballatori, and J. L. Boyer. Active, microtubule-dependent secretion of a fluorescent bile salt derivative in skate hepatocyte clusters. Am. J. Physiol. Gastrointest. Liver Physiol. 270: G887-G896, 1996.
14. Muller, M., T. Ishikawa, U. Berger, C. Klunemann, L. Lucka, A. Schreyer, C. Kannicht, W. Reutter, G. Kurz, and D. Keppler. ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt. J. Biol. Chem. 266: 18920-18926, 1991.
15. Muller, M., and P. L. M. Jansen. Molecular aspects of hepatobiliary transport. Am. J. Physiol. Gastrointest. Liver Physiol. 272: G1285-G1303, 1997.
16. Nishida, T., Z. Gatmaitan, M. Che, and I. M. Arias. Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system. Proc. Natl. Acad. Sci. USA 88: 6590-6594, 1991.
17. Noe, B., B. Hagenbuch, B. Stieger, and P. J. Meier. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc. Natl. Acad. Sci. USA 94: 10346-10350, 1997.
18. Ortiz, D. F., M. V. St. Pierre, A. Abdulmessih, and I. M. Arias. A yeast ATP-binding cassette-type protein mediating ATP-dependent bile acid transport. J. Biol. Chem. 272: 15358-15365, 1997.
19. Schneider, S., U. Schramm, A. Schreyer, H. P. Buscher, W. Gerok, and G. Kurz. Fluorescent derivatives of bile salts. I. Synthesis and properties of NBD-amino derivatives of bile salts. J. Lipid Res. 32: 1769-1779, 1991.
20. Schramm, U., A. Dietrich, S. Schneider, H. P. Buscher, W. Gerok, and G. Kurz. Fluorescent derivatives of bile salts. II. Suitability of NBD-amino derivatives of bile salts for the study of biological transport. J. Lipid Res. 32: 1755-1767, 1991.
21. Sellinger, M., N. Ballatori, and J. L. Boyer. Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea. Toxicol. Appl. Pharmacol. 107: 369-376, 1991.
22. Smith, D. J., M. Grossbard, E. R. Gordon, and J. L. Boyer. Taurocholate uptake by isolated skate hepatocytes: effect of albumin. Am. J. Physiol. Gastrointest. Liver Physiol. 252: G479-G484, 1987.
23. Smith, D. J., M. Grossbard, E. R. Gordon, and J. L. Boyer. Isolation and characterization of a polarized isolated hepatocyte preparation in the skate (Raja erinacea). J. Exp. Zool. 241: 291-296, 1987.
24. Song, C. S., W. Rubin, and A. Kappa. Plasma membranes of the rat liver. J. Cell Biol. 41: 124-132, 1969.
25. Stieger, B., B. O'Neill, and P. J. Meier. ATP-dependent bile salt transport in canalicular rat liver plasma membrane vesicles. Biochem. J. 284: 67-74, 1992.
26. Strautnieks, S. S., L. N. Bull, A. S. Knisely, S. Kocoshis, N. Dahl, H. Arnell, E. Sokal, K. Dahan, S. Childs, V. Ling, M. S. Tanner, A. F. Kagalwalla, A. Nemeth, J. Pawlowska, A. Baker, G. Mielivergani, N. B. Freimer, R. M. Gardiner, and R. J. Thompson. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat. Genet. 20: 233-238, 1998.
27. Tammar, A. R. Bile salts in fishes. Chem. Zool. 8: 595-661, 1974.
28. Wolters, H., F. Kuipers, M. J. H. Sloff, and R. J. Vonk. Adenosine triphosphate-dependent taurocholate transport in human liver plasma membranes. J. Clin. Invest. 90: 2321-2326, 1992.