Aromatic hydroxylation in PBN spin trapping by hydroxyl radicals and cytochrome P-450

Free Radical Biology and Medicine

Volumn 28, Issue 3, 2000, Pages 345-350

  Reinke, Lester A ^a   Moore, Danny R ^a   Sang, Hong ^b   Janzen, Edward G ^b   Kotake, Yashige ^b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF PHARMACY   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Drug metabolism; Free radicals; Hydroxyl radicals; Mixed function oxidation; Phenyl N tert butylnitrone; Spin trapping

Indexed keywords

4 HYDROXY N TERT BUTYL ALPHA PHENYLNITRONE; BENZOIC ACID; CATALASE; CYTOCHROME P450; DEFEROXAMINE; DRUG METABOLITE; FERROUS GLUCONATE; FERROUS SULFATE; FREE RADICAL; HYDROGEN PEROXIDE; HYDROXYL RADICAL; N TERT BUTYL ALPHA PHENYLNITRONE; PHENOL DERIVATIVE; PROADIFEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE LEVEL; BLOOD LEVEL; CONTROLLED STUDY; DRUG CONJUGATION; DRUG METABOLISM; HYDROXYLATION; LIVER LEVEL; LIVER MICROSOME; MALE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; REACTION ANALYSIS; SPIN TRAPPING; URINE LEVEL;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; HYDROGEN PEROXIDE; HYDROXYL RADICAL; HYDROXYLATION; IRON; MALE; MICROSOMES, LIVER; NITROGEN OXIDES; RATS; RATS, WISTAR; SPIN LABELS;

ANIMALIA;

EID: 0033955235     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00248-8     Document Type: Article

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