The ubiquitin-activating enzyme E1 homologous genes on the mouse Y Chromosome (Ube1y) represent one functional gene and six partial pseudogenes

Mammalian Genome

Volumn 11, Issue 2, 2000, Pages 164-168

  Lévy, Nicolas ^a,b   Navarro, André ^a,b   Bishop, Colin E ^c   Mitchell, Michael J ^a  

^a INSERM   (France)

^b TIMONE HOSPITAL   (France)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE ACTIVATION; GENE DELETION; GENE FUNCTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PSEUDOGENE; SPERMATOGENESIS; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION; Y CHROMOSOME;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, SOUTHERN; EXONS; INTRONS; LIGASES; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; PSEUDOGENES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; Y CHROMOSOME;

EID: 0033955162     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003350010031     Document Type: Article

References (28)

1. Agulnik AI, Mitchell MJ, Lerner JL, Woods DR, Bishop CE (1994) A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. Hum Mol Genet 3, 873-878
2. Agulnik AI, Longepied G, Ty MT, Bishop CE, Mitchell MJ (1999) Mouse H-Y encoding Smcy gene and its X chromosome homolog Smcx. Mamm Genome 10, 926-929
3. Charlesworth B (1978) Model for evolution of Y chromosomes and dosage compensation. Proc Natl Acad Sci USA 75, 5618-5622
4. Ciechanover A (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21
5. Evans EP, Burtenshaw MD, Cattanach BM (1982) Meiotic crossing-over between the X and Y chromosomes of male mice carrying the sex-reversing (Sxr) factor. Nature 300, 443-445
6. Foster JW, Brennan FE, Hampikian GK, Goodfellow PN, Sinclair AH et al. (1992) Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupials. Nature 359, 531-533
7. Handley-Gearhart PM, Stephen AG, Trausch-Azar JS, Ciechanover A, Schwartz AL (1994a) Human ubiquitin-activating enzyme, E1. Indication of potential nuclear and cytoplasmic subpopulations using epitope-tagged cDNA constructs. J Biol Chem 269, 33171-33178
8. Handley-Gearhart PM, Trausch-Azar JS, Ciechanover A, Schwartz AL (1994b) Rescue of the complex temperature-sensitive phenotype of Chinese hamster ovary E36ts20 cells by expression of the human ubiquitin-activating enzyme cDNA. Biochem J 304, 1015-1020
9. Kalderon D, Roberts BL, Richardson WD, Smith AE (1984) A short amino acid sequence able to specify nuclear location. Cell 39, 499-509
10. Kent-First MG, Maffitt M, Muallem A, Brisco P, Shultz J et al. (1996) Gene sequence and evolutionary conservation of human SMCY. Nat Genet 14, 128-129
11. King TR, Christianson GJ, Mitchell MJ, Bishop CE, Scott D et al. (1994) Deletion mapping by immunoselection against the H-Y histocompatibility antigen further resolves the Sxra region of the mouse Y chromosome and reveals complexity of the Hya locus. Genomics 24, 159-168
12. Lahn BT, Page DC (1997) Functional coherence of the human Y chromosome. Science 278, 675-680
13. Mazeyrat S, Mitchell M (1998) Rodent Y chromosome TSPY gene is functional in rat and non-functional in mouse. Hum Mol Genet 7, 557-562
14. Mazeyrat S, Saut N, Sargent C, Grimmond S, Longepied G et al. (1998) The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa region. Hum Mol Genet 7, 1713-1724
15. Mitchell MJ, Bishop CE (1992) A structural analysis of the Sxr region of the mouse Y chromosome. Genomics 12, 26-34
16. Mitchell MJ, Woods DR, Tucker PK. Opp JS, Bishop CE (1991) Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1. Nature 354, 483-486
17. Mitchell MJ, Woods DR, Wilcox SA, Graves JAM, Bishop CE (1992) Marsupial Y chromosome encodes a homologue of the mouse Y-linked candidate spermatogenesis gene Ubely. Nature 359, 528-531
18. Mitchell MJ, Wilcox SA, Watson JM, Lerner JL, Woods DR et al. (1998) The origin and loss of the ubiquitin-activating enzyme gene on the mammalian Y chromosome. Hum Mol Genet 7, 429-434
19. Nishitani H, Goto H, Kaneda S, Yamao F, Seno T et al. ( 1992) tsBN75 and tsBN423, temperature-sensitive X-linked mutants of the BHK21 cell line, can be complemented by the ubiquitin-activating enzyme E1 cDNA. Biochem Biophys Res Commun 184, 1015-1021
20. Odorisio T, Mahadevaiah SK, McCarrey JR, Burgoyne PS (1996) Transcriptional analysis of the candidate spermatogenesis gene Ubely and of the closely related Ubelx shows that they are coexpressed in spermatogonia and spermatids hut are repressed in pachytene spermatocytes. Dev Biol 180, 336-343
21. Roberts C, Weith A, Passage E, Michot JL, Mattei M et al. (1988) Molecular and cytogenetic evidence for location of Tdy and Hya on the mouse Y chromosome short arm. Proc Natl Acad Sci USA 85, 6446-6449
22. Singh L, Jones KW (1982) Sex reversal in the mouse (Mus musculus) is caused by a recurrent nonreciprocal crossover involving the X and an aberrant Y chromosome. Cell 28, 205-216
23. Stephen AG, Trausch-Azar JS, Ciechanover A, Schwanz AL (1996) The ubiquitin-activating enzyme E1 is phosphorylated and localized to the nucleus in a cell cycle-dependent manner. J Biol Chem 271, 15608-15614
24. Sutcliffe MJ, Burgoyne PS (1989) Analysis of the testis of H-Y negative XOSxrb mice suggests that the spermatogenesis gene (Spy) acts during the differentiation of the A spermatogonia. Development 107, 373-380
25. Tucker PK, Lundrigan BL (1993) Rapid evolution of the sex-determining locus in Old World mice and rats. Nature 364, 715-717
26. Tucker PK, Phillip KS, Lundrigen BL (1992) A mouse Y chromosome pseudogene is related to human ubiquitin-activating enzyme. Mamm Genome 3, 28-35
27. Whitfield LS, Lovell-Badge R, Goodfellow P (1993) Rapid sequence evolution of the mammalian sex-determining gene SRY. Nature 364, 713-715
28. Zacksenhaus E, Sheinin R (1990) Molecular cloning, primary structure and expression of the human X linked A1S9 gene cDNA which complements the ts A1S9 mouse L cell defect in DNA replication. EMBO J 9, 2923-2929.