Multi-night exposure to 60 Hz magnetic fields: Effects on melatonin and its enzymatic metabolite

Journal of Pineal Research

Volumn 28, Issue 1, 2000, Pages 1-8

  Graham, Charles ^a,b   Cook, Mary R ^a   Sastre, Antonio ^a   Riffle, Donald W ^a   Gerkovich, Mary M ^a  

^a MIDWEST RESEARCH INSTITUTE   (United States)

^b MRI Planning   (United States)

Author keywords

Adaptation; Cancer; Circadian rhythm; EMF; Human; Neuroendocrine

Indexed keywords

6 HYDROXYMELATONIN O SULFATE; MELATONIN;

ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ELECTROMAGNETIC FIELD; EXPOSURE; HORMONE URINE LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; METABOLITE; NIGHT;

ADOLESCENT; ADULT; CIRCADIAN RHYTHM; DOUBLE-BLIND METHOD; ELECTROMAGNETIC FIELDS; HUMANS; MALE; MELATONIN; PINEAL GLAND;

EID: 0033955073     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079X.2000.280101.x     Document Type: Article

References (35)

1. Akerstedt, T., B. Arnetz, G. Ficca, L.-E. Paulsson (1997) Low frequency electromagnetic fields suppress SWS. J. Sleep Res. 26:260-260.
2. Arnetz, B.B., M. Berg. (1996) Melatonin and adrenocorticotropic hormone levels in video display unit workers during work and leisure. J. Occup. Environ. Med. 38:1108-1110.
3. Arendt, J. (1995) Melatonin and the Mammalian Pineal Gland. Chapman and Hall, London, 209 p.
4. Brzezinski, A. (1997) Melatonin in humans. New Engl. J. Med. 336:186-195.
5. Barnes, RG, M.J. Forbes, J. Arendt (1998) Shift type and season affect adaptation of the 6-sulphatoxymelatonin rhythm in offshore oil rig workers. Neurosci. Lett. 252:179 182.
6. Burch, J.B., J.S. Reif, M.G. Yost, T.J. Keefe, C.A. Pitrat (1998) Nocturnal excretion of a urinary melatonin metabolite in electric utility workers. Scand. J. Work Environ. Health 24:183-189.
7. Cagnacci, A. (1996) Melatonin in relation to physiology in adult humans. J. Pineal Res. 21:200 213.
8. Cook, M.R., C. Graham, H.D. Cohen, M.M. Gerkovich (1992) A replication study of human exposure to 60 Hz fields: Effects on neurobehavioral measures. Bioelectromagnetics 13:261-285.
9. Dawson, T.W., K. Caputa, M.A. Stuchly (1997) Influence of human model resolution on computed currents induced in organs by 60 Hz magnetic fields. Bioelectromagnetics 18:478-490.
10. Dietrich, F. (1998) Quality Assurance. In: EMF Engineering Review Symposium: Status and Summary of EMF Engineering Research. US Department of Energy, Office of Energy Management, Vol. 5, pp. 1-11
11. Doynov, P., H.D. Cohen, M.R. Cook, C. Graham (1999) Test facility for human exposure to AC and DC magnetic fields. Bioelectromagnetics 20:101-111.
12. Gailey, P., A. Sastre, R.E. McGaughy (1997) Internal electric fields produced by EMF, dosimetry, and endogenous fields. In: EMF Science Review Symposium Breakout Group Reports for Theoretical Mechanisms and In Vitro Research Findings. C. Portier, M. Wolfe, eds. National Institute of Environmental Health Sciences, Research Triangle Park, NC, pp. 55-70.
13. Graham, C., M.R. Cook, H.D. Cohen, M.M. Gerkovich (1994) A dose response study of human exposure to 60 Hz electric and magnetic fields. Bioelectromagnetics 15:447 463.
14. Graham, C., M.R. Cook, D.W. Riffle, M.M. Gerkovich, H.D. Cohen (1996) Nocturnal melatonin levels in human volunteers exposed to intermittent 60 Hz magnetic fields. Bioelectromagnetics 17:263 273.
15. Graham, C., M.R. Cook, D.W. Riffle, M.M. Gerkovich, H.D. Cohen (1997) Human melatonin during continuous magnetic field exposure. Bioelectromagnetics 18:166-171.
16. Graham, C., M.R. Cook, R. Kavet, A. Sastre, D.K. Smith (1998) Prediction of nocturnal plasma melatonin from morning urinary measures. J. Pineal Res. 24:230-238.
17. Hardeland, R., R.J. Reiter, B. Poeggeler, D.-X. Tan (1993) The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances. Neurosci. Biobehav. Rev. 17:347-357.
18. Kato, A., K. Honma, T. Skigemitsu, Y. Shiga (1994) Horizontal or vertical 50 Hz 1-UT magnetic fields have no effect on pineal gland or plasma melatonin concentrations of albino rats. Neurosci. Lett. 168:205-208.
19. Kaune, W., S. Davis, R. Stevens (1997) Relation between residential magnetic fields, light-at-night, and nocturnal urine melatonin levels in women. EPRI Report TR-107242-V1
20. Klante, G., T. Brinschwitz, K. Secci, F. Wollnik (1997) Creatinine is an appropriate reference for urinary sulphatoxymelatonin of laboratory animals and humans. J. Pineal Res. 23:191 197.
21. Kumlin, T., N.H. Hansen, M. Kilpelainen, S. Kukkonen, J. Laitinen, R.W. Stevens, B.W. Wilson, J. Juutilainen (1997) Night-time melatonin production in female workers exposed to magnetic fields. In: 5th Nordic Workshop, Biological Effects of LF EMF, A. Johansson, G. Oftcdal, eds. Norwegian Radiation Protection Authority, Oslo, Norway, pp. 67 68.
22. Lai, H., N.P. Singh (1997) Melatonin and N-tert-butyl-α-phenylnitrone block 60 Hz magnetic field-induced DNA single and double strand breaks in rat brain cells. J. Pineal Res. 22:152 162.
23. Lushington, K., D. Dawson, N. Engel, L. Lack (1996) Urinary 6-sulfatoxymelatonin cycle-to-cycle variability. Chronobiol. Int. 13:411 421.
24. Midwinter, M.J., J. Arendt (1991) Adaptation of the melatonin rhythm in human subjects following night-shift work in Antarctica. Neurosci. Lett. 122:195 198.
25. Pfluger, D.H., C.E. Minder (1996) Effects of exposure to 16.7 Hz magnetic fields on urinary 6-hydroxymelatonin sulfate excretion of Swiss railway workers. J. Pineal Res. 21:91 100.
26. Portier, C.J., M.S. Wolfe (1998) Assessment of Health Effects from Exposure to Power-Line Frequency Electric and Magnetic Fields: NIEHS Working Group Report. NIH Publ. No. 98 3981.
27. Reiter, R., L. Tang, J.J. Garcia, A. Munoz-Hoyos (1997) Pharmacological actions of melatonin in oxygen-radical pathophysiology. Life Sci. 60:2255-2271.
28. Reiter, R.J. (1998) Melatonin and human reproduction. Ann. Med. 30:103 108.
29. Sastre, A., M.R. Cook, C. Graham (1998) Nocturnal exposure to intermittent 60 Hz magnetic fields alters human cardiac rhythm. Bioelectromagnetics 19:98 106.
30. Selmaoui, B., Y. Touitou (1995) Sinusoidal 50 Hz magnetic fields depress rat pineal NAT activity and serum melatonin: Role of duration and intensity of exposure. Life Sci. 57:1351-1358.
31. Selmaoui, B., J. Lambrozo, Y. Touitou (1996) Magnetic fields and pineal function in humans: Evaluation of nocturnal acute exposure to ELF magnetic fields on serum melatonin and urinary aMT6s circadian rhythms. Life Sci. 58:1539 1549.
32. Stevens, R.G. (1987) Electric power use and breast cancer: A hypothesis. Am. J. Epidemiol. 125:556 561.
33. Stevens, R.G., B.W. Wilson, L.E. Anderson (1997) The Melatonin Hypothesis: Breast Cancer and the Use of Electricity. Buttelle Press, Columbus, OH, 760 p.
34. Waldhauser, F., Dietzel, M. (1985) Daily and annual rhythms in human melatonin secretion: Role in puberty control. In: The Medical and Biological Effects of Light. R.J. Wurtman, M.J. Baum, J.T. Potts, Jr., eds. Annals New York Acadamy of Science, New York, Vol. 453, pp. 205-214
35. Wilson, B.W., C.W. Wright, J.E. Morris, R.L. Buschbom, D.P. Brown, D.L. Miller, R. Sommers-Flannigan, L.E. Anderson (1990) Evidence for an effect of ELF electromagnetic fields on human pineal gland function. J. Pineal Res. 9:259-269.