The molar vesicle fluid contains the β-core fragment of human chorionic gonadotropin

Placenta

Volumn 21, Issue 1, 2000, Pages 79-87

  Khan, S ^a   Katabuchi, H ^a   Araki, M ^a   Ohba, T ^a   Koizumi, T ^b   Okamura, H ^a   Nishimura, R ^b  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b Hyogo Institute of Clinical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CHORIONIC GONADOTROPIN BETA SUBUNIT; HORMONE ANTIBODY; LECTIN;

ARTICLE; CLINICAL ARTICLE; CYTOPLASM; FEMALE; GEL CHROMATOGRAPHY; HORMONE BINDING; HUMAN; HYDATIDIFORM MOLE; IMMUNOREACTIVITY; LECTIN BINDING; MACROPHAGE; PERITONEUM; PRIORITY JOURNAL; STROMA; SUPERNATANT; URINALYSIS;

EID: 0033954825     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.1999.0453     Document Type: Article

References (28)

1. Alfthan H., Stenman U.H. Pregnancy serum contains the β-core fragment of human choriogonadotropin. J Clin Endocrinol Metab. 70:1990;783-787.
2. Alfthan H., Haglund C., Roberts P., Stenman U.H. Elevation of free β subunit of human choriogonadotropin and core β fragment of human choriogonadotropin in the serum and urine of patients with malignant pancreatic and billiary disease. Cancer Res. 52:1992;4628-4633.
3. Birken S., Armstrong E.G., Kolks M.A., Cole L.A., Agosto G.M., Krichevsky A., Vaitukaitis J.L., Canfield R.E. Structure of the human chorionic gonadotropin β-subunit fragment from pregnancy urine. Endocrinology. 123:1988;572-583.
4. Braunstein G.D., Frumovitz M., Do L., Seliktar J., Gonzales E. The β-core fragment of human chorionic gonadotropin is not complexed to macromolecules in amniotic fluid. J Clin Endocrinol Metab. 78:1994;1349-1353.
5. Cole L.A., Birken S. Origin and occurrence of human chorionic gonadotropin β-subunit core fragment. Mol Endocrinol. 2:1988;825-830.
6. Cole L.A., Wang Y., Elliott M., Latif M., Chambers J.T., Chambers S.K., Schwartz P.E. Urinary human chorionic gonadotropin free β-subunit and β-core fragment: a new marker of gynecological cancers. Cancer Res. 48:1988;1356-1360.
7. Cole L.A., Kardana A., Park S-Y, Braunstein G.D. The deactivation of hCG by nicking and dissociation. J Clin Endcrinol Metab. 76:1993;704-710.
8. de Medeiros S.F., Amato F., Matthews C.D., Norman R.J. Comparison of specific immunoassays for detection of the β-core human chorionic gonadotropin fragment in body fluids. J Endocrinol. 135:1992a;161-174.
9. de Medeiros S.F., Amato F., Bacich D., Wang L., Matthews C.D., Norman R.J. Distribution of the β-core human chorionic gonadotropin fragment in human body fluids. J Endocrinol. 135:1992b;175-188.
10. Endo T., Nishimura R., Saito S., Kanazawa K., Nomura K., Katsuno M., Shii K., Mukhapadhay K., Baba S., Kobata A. Carbohydrate structure of β-core fragment of human choriogonadotropin isolated from a pregnant individual. Endocrinology. 130:1992;2052-2058.
11. Franchimont P., Gaspard U., Reuter A., Heynen G. Polymorphism of protein and polypeptide hormone. Clin Endocrinol. 1:1972;315-336.
12. Fukumatsu Y., Katabuchi H., Miyamura S., Matsuura K., Okamura H. Activated macrophages in the peritoneal fluid of women with endometriosis: Examination of the intracytoplasmic localization of endogenous peroxidase and interleukin-1. Acta Obstet Gynaecol Jpn. 44:1992;529-536.
13. Good A., Ramos-Uribe M., Ryan R.J., Kempers R.D. Molecular forms of human chorionic gonadotropin in serum, urine, and placental extracts. Fertil Steril. 28:1977;846-850.
14. Iles R.K., Javid M.K., Gunn L.K., Chard T. Cross-reaction with luteinizing hormone β-core is responsible for the age-dependent increase of immunoreactive β-core fragment of human chorionic gonadotropin in women with nonmalignant conditions. Clin Chem. 45:1999;532-538.
15. Kardana A., Cole L.A. Serum hCGβ-core fragment is masked by associated macromolecules. J Clin Endocrinol Metab. 71:1990;1393-1395.
16. Kardana A., Cole L.A. Human chorionic gonadotropin β-subunit nicking enzymes in pregnancy and cancer patient serum. J Clin Endcrinol Metab. 79:1994;761-767.
17. Katabuchi H., Naito M., Miyamura S., Takahashi K., Okamura H. Macrophages in human chorionic villi. Prog Clin Biol Res. 296:1989;453-458.
18. Katabuchi H., Fukumatsu Y., Araki M., Mizutani H., Ohba T., Okamura H. Localization of chorionic gonadotropin in macrophages of the human chorionic villi. Endocr J. 41:1994;141-153.
19. Kato Y., Braunstein G.D. β-core fragment is a major form of immunoreactive urinary chorionic gonadotropin in human pregnancy. J Clin Endocrinol Metab. 66:1988;1197-1201.
20. Kliman H.J., Lee K.S., Meaddough E.L., Cole L.A. hCG degradation in the human chorionic villous β-core. Abstracts of Symposium on Glycoprotein Hormones: structure, function and clinical implications. 1993.
21. Lefort G.P., Stolk J.M., Nisula B.C. Evidence that desialylation and uptake by hepatic receptors for galactose-terminated glycoproteins are immaterial to the metabolism of human choriogonadotropin in the rat. Endocrinology. 115:1984;1551-1557.
22. Lefort G.P., Stolk J.M., Nisula B.C. Renal metabolism of the β-subunit of human choriogonadotropin in the rat. Endocrinology. 119:1986;924-931.
23. MaKay D.G., Roby C.C., Hertig T.H., Richardson M.V. Studies of the function of early human trophoblasts. I. Observations on the chemical composition of the fluid of hydatidiform moles. Am J Obstet Gynecol. 69:1955;722-734.
24. Nishimura R., Kitajima T., Hasegawa K., Takeuchi K., Mochizuki M. Molecular forms of human chorionic gonadotropin in choriocarcinoma serum and urine. Jpn J Cancer Res. 80:1989;968-974.
25. Nishimura R., Koizumi T., Morisue K., Yamanaka N., Lalwani R., Yoshimura M., Nakagawa T., Shii M., Hasegawa K., Baba S. Expression and secretion of the β subunit of human chorionic gonadotropin by bladder carcinoma in vivo and in vitro. Cancer Res. 55:1995;1479-1484.
26. O'Conner J.F.O., Kovalevskaya G., Birken S., Schlatterer J.P., Schechter D., McMahon D.J., Canfield R.E. The expression of the urinary forms of human luteinizing hormone beta fragment in various populations as assessed by a specific immunoradiometric assay. Human Reprod. 13:1998;826-835.
27. Wehmann R.E., Blithe D.L., Akar A.H., Nisula B.C. Disparity between β-core levels in pregnancy urine and serum: Implications for the origin of urinary β-core. J Clin Endocrinol Metab. 70:1990;371-378.
28. Yoshimura M., Nishimura R., Murotani A., Miyamoto Y., Nakagawa T., Hasegawa K., Koizumi T., Shii M., Baba S., Tsubota N. Assessment of urinary β-core fragment of human chorionic gonadotropin as a new tumor marker of lung cancer. Cancer. 73:1994;2745-2752.