VEGF, flt-1, and KDR/flk-1 as prognostic indicators in endometrial carcinoma

Gynecologic Oncology

Volumn 76, Issue 1, 2000, Pages 33-39

  Fine, B A ^a   Valente, P T ^a   Feinstein, G I ^a   Dey, T ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Angiogenesis; Endometrial carcinoma; VEGF

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; ENDOMETRIUM CARCINOMA; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; METASTASIS; PRIORITY JOURNAL; PROGNOSIS;

EID: 0033954660     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1999.5658     Document Type: Article

References (41)

1. Fidler, I, J: Molecular biology of cancer: invasion and metastasis. In De Vita, J, R, Hellman, S, Rosenberg, S, A (eds): Cancer Principles and Practice of Oncology, Lippincott-Raven, Philadelphia, 135-152, 1997.
2. Koochekpour S, Merzak A, Pilkington G J. Vascular endothelial growth factor production is stimulated in response to growth factors in human glioma cells. Oncol Rep. 2:1995;1059-1061.
3. Tsai J C, Goldman C K, Gillespie G Y. Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PEDGF-BB, AND Bfgf. J Neurosurg. 82:1995;864-873.
4. Cohen T, Nahari D, Cerem L W, Neufeld G, Levi B Z. Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem. 271:1996;736-741.
5. Weidner N, Semple J P, Welch W R, Rolkman J. Tumor angiogenesis and metastasis - correlation in invasive breast cancer. N Engl J Med. 324:1991;1-8.
6. Weidner M, Carroll P R, Flax J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol. 143:1993;401-409.
7. Macchiarini P, Fontanini G, Hardin M J. Relation of neovaxcularization to metastasis on non-small-cell lung cancer. Lancet. 340:1992;145-146.
8. Srivastava A, Laidler P, Davies R P. The prognostic significance of tumor vascularity in intermediate-thickness (.76-4.0 mm thick) skin melanoma: a quantitative histologic study. Am J Pathol. 133:1988;419-423.
9. Guidi A J, Abu-Jawdeh G, Tognazzi K, Dvorak H F, Brown L F. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma. Cancer. 78:1996;454-460.
10. Ferrara N, Henzel W J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun. 161:1989;851-859.
11. Ploüet J, Schilling J, Gospodarowicz D. Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT20 cells. EMBO J. 8:1989;3801-3807.
12. Silverberg S G, Major F J, Blessing J A. Carcinosarcoma (malignant mixed mesodermal tumor) of the uterus: a Gynecologic Oncology Group pathologic study of 203 cases. Int J Gynecol Pathol. 9:1990;1.
13. Hendrickson M, Ross J, Eifel P. Uterine papillary serous carcinoma. A highly malignant form of endometrial adenocarcinoma. Am J Surg Pathol. 6:1982;93-108.
14. Polverini P I, Leibovich S J. Induction of neovascularization in vivo and endothelial cell proliferation in vitro by tumor-associated macrophages. Lab Invest. 51:1984;635-642.
15. Polverini P J, Cotran R S, Gimbron M A Jr, Unanue E R. Activated macrophages induced vascular proliferation. Nature. 269:1977;804-806.
16. Starkey J R, Crowle P K, Taubenberger S. Mast-cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis. Int J Cancer. 42:1988;48-52.
17. Welch, D, R, Schissel, D, J, Howey, R, P, Tumor-elicited polymorphonuclear cells, in contrast to 'normal' circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells, Proc Natl Acad Sci USA, 86: 5859, - 5863.
18. Briozzo P, Badet J, Capony F, Pieri I, Montcourrier P, Barritault D. MCF7 mammary cancer cells respond to bFGF and internalize it following its release from the extracellular matrix: a permissive role for cathepsin D. Exp Cell Res. 194:1991;252-259.
19. deVries C, Escobedo J A, Ureno H, Houck K A, Ferrara N, Williams L T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science. 255:1992;989-991.
20. Terman B I, Vermazen M D, Carrion M E. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun. 34:1992;1578-1586.
21. Shibuya M, Yamaguchi S, Yamane A. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase (flt) closely related to the fms family. Oncogene. 8:1990;519-527.
22. Matthews W, Jordan C T, Gavin M, Jenkins N A, Copeland N G, Lemischka I R. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic lineage to c-kit. Proc Natl Acad Sci USA. 88:1991;9026-9030.
23. Quinn T, Peters K G, deVries C, Ferrara N, Williams L T. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA. 90:1993;7533-7537.
24. Millauer B, Wizigmann-Voos S, Schnurch H. High affinity binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 72:1993;835-846.
25. Fong G-H, Rassant J, Gertenstein M, Breitman M. Role of Flt-1 receptor tyrosine kinase in regulation of assembly of vascular endothelium. Nature. 376:1995;66-67.
26. Shalabi F, Rossant J, Yamaguchi T P. Failure of blood island formation and vasculogenesis in Flk-1 deficient mice. Nature. 376:1995;62-66.
27. Ferrara N, Houck K, Jakeman L, Leung D W. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrinol Rev. 13:1992;18-32.
28. Brown L F, Berse B, Jackman R W. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res. 53:1993;4727-4735.
29. Suzuki K, Hayashi N, Miyamoto Y. Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res. 56:1996;3004-3009.
30. Plate K H, Breier G, Weich H A, Risau W. Vascular endothelial growth is a potential tumour angiogenesis factor in vivo. Nature. 359:1992;845-847.
31. Doldi N, Bassan M, Gulisano M, Broccoli V, Boncinellii E, Ferrari A. Vascular endothelial growth factor messenger ribonucleic acid expression in human ovarian and endometrial cancer. Gynecol Endocrinol. 10:1996;375-382.
32. Toi M, Hoshima S, Takayanagi T, Tominaga T. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn J Cancer Res. 85:1994;1045-1049.
33. Maeda K, Chung Y S, Ogawa Y. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer. 77:1996;858-863.
34. Toi M, Inada K, Suzuki H. Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res Treat. 36:1995;193-204.
35. Guidi A J, Abu-Jawdeh G, Berse B. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst. 87:1995;1237-1245.
36. McCulloch P, Choy A, Martin L. Association between tumor angiogenesis and tumor cell shedding into effluent venous blood during breast cancer surgery. Lancet. 346:1995;1334-1335.
37. Creasman W T, Morrow C P, Bundy B N. Surgical pathologic spread patterns of endometrial cancer (a Gynecologic Oncology Group study). Cancer. 60:1987;2035.
38. Boronow R C, Morrow C P, Creasman W T. Surgical staging in endometrial cancer: clinical-pathologic findings of a prospective study. Obstet Gynecol. 63:1984;825.
39. Bucy G S, Mendenhall W M, Morgan L S. Clinical Stage I and II endometrial carcinoma treated with surgery and/or radiation therapy: analysis of prognostic and treatment-related factors. Gynecol Oncol. 33:1989;290.
40. Piver M S, Lele S B, Barlow J J. Para-aortic lymph node evaluation in stage I endometrial carcinoma. Gynecol Oncol. 59:1982;97.
41. Yoshiji H, Harris S R, Thorgeirsson U P. Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells. Cancer Res. 57:1997;3924-3928.