Thiorphan, an inhibitor of neutral endopeptidase/enkephalinase (CD10/CALLA) enhances cell proliferation in bone marrow cultures of patients with acute leukemia in remission

Haematologia

Volumn 30, Issue 1, 2000, Pages 1-10

  Stanovic S ^a   Boranic M ^a   Petrovecki M ^b   Batinic D ^b   Skodlar, J ^b   Nemet, D ^b   Labar, B ^b  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b KBC Zagreb   (Croatia)

Author keywords

Acute leukemia; CD10; GM CFU; Neprilysin (membrane metallo endopeptidase: EC 3.4.24.11); Thiorphan

Indexed keywords

ENKEPHALINASE INHIBITOR; THIORPHAN;

ACUTE LEUKEMIA; ARTICLE; BONE MARROW CELL; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA REMISSION; STEM CELL;

EID: 0033953570     PISSN: 00176559     EISSN: None     Source Type: Journal    
DOI: 10.1163/15685590051129814     Document Type: Article

References (30)

1. Letarte, M., Vera, S., Tran, R., Addis, J. B. L., Onizuka, R. J., Quackenbush, E. J., Jongeneel, C., McInnes, R. R., Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase, J. Exp. Med. 168 1247 (1988).
2. Shipp, M. A., Vijayaraghavan, J., Schmidt, E. V., Masteller, E. L., D'Adamio, L., Hersh, L. B., Reinherz, E. L., Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): Direct evidence by cDNA transfection analysis, Proc. Natl. Acad. Sci. USA 86 297 (1989).
3. Arber, D. A., Weiss, L. M., CD10 - A Review, Appl. Immunohistochem. 5, 125 (1997).
4. LeBien, T. W., McCormack, R. T., The common acute lymphoblastic leukemia antigen (CD10) - Emancipation from a functional enigma, Blood 73, 625 (1989).
5. Macedo, A., Orfao, A., Ciudad, J., Gonzalez, M., Vidriales, B., Lopezberges, M. C., Martinez, A., Landolfi, C., Canizo, C., Sanmiguel, J. F., Phenotypic analysis of CD34 subpopulations in normal human bone marrow and its application for the detection of minimal residual disease, Leukemia 9, 1896 (1995).
6. Casale, L., Cardozo, C., Kalb, T., Lesser, M., Quantitation of endopeptidase 24.11 and endopeptidase 24.15 in human blood leukocytes, Enzyme Protein 48, 143 (1994-95).
7. Tran-Paterson, R., Boileau, G., Giguere, V., Letarte, M., Comparative levels of CALLA/neutral endopeptidase on normal granulocytes, leukemic cells, and transfected COS-1 cells, Blood 76, 775 (1990).
8. De Gouw, H. W. F. M., Diamant, Z., Kuijpers, E. A. P., Sont, J. K., Sterk, P. J., Role of neutral endopeptidase in exercise-induced bronchoconstriction in asthmatic subjects, J. Appl. Physiol. 81, 673 (1996).
9. Diamant, Z., Van der Veen, H., Kuijpers, E. A. P., Bakker, P. F., Sterk, P. J., The effect of inhaled thiorphan on allergen-induced airway responses in asthmatic subjects, Clin. Exp. Allergy 26, 525 (1996).
10. Mentlein, R., Roos, T., Proteases involved in the metabolism of angiotensin II, bradykinin, calcitonin gene-related peptide (CGRP), and neuropeptide Y by vascular smooth muscle cells, Peptides 17, 709 (1996).
11. Nagatomo, Y., Kitamura, K., Kangawa, K., Fujimoto, Y., Eto, T., Proadrenomedullin N-terminal 20 peptide is rapidly cleaved by neutral endopeptidase, Biochem. Biophys. Res. Commun. 223, 539 (1996).
12. Roques, B. P., Noble, F., Dauge, V., Fournie-Zaluski, M.-C., Beaumont, A., Neutral endopeptidase 24.11: structure, inhibition and experimental and clinical pharmacology, Peptides 45, 87 (1993).
13. Beaumont, A., Brouet, J. C., Roques, B. P., Neutral endopeptidase 24.11 and angiotensin converting enzyme like activity in Calla positive and Calla negative lymphoid cells, Biochem. Biophys. Res. Commun. 160, 1323 (1989).
14. Li, C., Hersh, L. B., Neprilysin: Assay methods, purification, and characterization, Methods Enzym. 248, 253 (1995).
15. Helene, A., Milhiet, P.-E., Haouas, H., Boucheix, C., Beaumont, A., Roques, B. P., Effects of monoclonal antibodies raised against the common acute lymphoblastic leukemia antigen on endopeptidase-24.11 activity, Biochem. Pharmacol. 43, 809 (1992).
16. Milhiet, P.-E., Beaumont, A., Garbay-Jaureguiberry, C., Roques, B. P., Increase of neutral endopeptidase-24.11 with cellular density and enzyme modulation with an inhibitor on human REH6 cell line, Biochem. Pharmacol. 43, 1711 (1992).
17. Boranić, M., Krizanac-Bengez, LJ., Gabrilovac, J., Marotti, T., Breljak, D., Enkephalins in hematopoiesis, Biomed. Pharmacother. 51, 29 (1997).
18. Petrovečki, M., Nemet, D., Kolevska, T., Marušić, M., Granulocyte-monocyte colony forming unit content of autologous bone marrow transplants in patients with haematological malignancy, Eur. J. Clin. Chem. Clin. Biochem. 33, 687 (1995).
19. Coutinho, L. H., Gilleece, M. H., DeWynter, E. A., Will, A., Testa, N. G., Clonal and long-term cultures using human bone marrow, in: Haematopoiesis, A Practical Approach, Testa, N.G., Molineux, G. (Eds), p. 173. Oxford University Press, Oxford, New York, Tokyo (1993).
20. Stanović, S., Boranić, M., Petrovečki, M., Skodlar, J., Golubić-Ćepulić, B., Nemet, D., Labar, B., Thiorphan stimulates clonal growth of GM-CFU in short term cultures of bone marrow from a healthy donor and patients with non-Hodgkin lymphoma, Biomed. Pharmacother. 52, 397 (1998).
21. Križanac-Bengez, LJ., Boranić, M., Enkephalinase-blocking agent thiorphan affects cell growth and differentiation in long term culture of mouse bone marrow, Biomed. Pharmacother. 49, 375 (1995).
22. Ishimaru, F., Potter, N. S., Shipp, M. A., Phorbol ester-mediated regulation of CD10/neutral endopeptidase transcripts in acute lymphoblastic leukemias, Exp. Hematol. 24, 43 (1996).
23. Erdös, E. G., Wagner, B., Harbury, C. B., Painter, R. G, Skidgel, R. A., Fa, X.-G., Down-regulation and inactivation of neutral endopeptidase 24.11 (enkephalinase) in human neutrophils, J. Biol. Chem. 264, 14519 (1989).
24. Ernst, T. J., Ritchie, A., Demetri, G. D., Griffin, J. D., Regulation of granulocyte-and monocyte-colony stimulating factor mRNA levels in human blood monocytes is mediated primarily at a post-transcriptional level, J. Biol., Chem. 264, 5700 (1989).
25. Delikat, S. E., Galvani, D. W., Zuzel, M., A function of CD10 on bone marrow stroma, Br. J. Haematol. 87, 655 (1994).
26. Pierart, M. E., Najdovski, T., Appelboom, T. E., Deschodt-Lanckman, M. M., Effect of human endopeptidase 24.11 ("enkephalinase") on IL-1-induced thymocyte proliferation acitivity, J. Immunol. 140, 3808 (1988).
27. Kuis, W., Villiger, M. P., Leser, H. G., Lotz, M., Differential processing of proenkephalin-A by human peripheral blood monocytes and T lymphocytes, J. Clin. Invest. 88, 817 (1991).
28. Vindrola, O., Padrós, M. R., Steri-Prync, A., Ase, A., Finkielman, S., Nahmod, V., Proenkephalin system in human polymorphonuclear cells, J. Clin. Invest. 86, 531 (1990).
29. Vaškû, A., Souček, M., Znojil, V., Řiháček, Cīdl, K., Střelcová, L., Vácha, L., Does angiotensin-I converting enzyme inhibitor therapy have an antiproliferative effect on blood-forming bone marrow? Exp. Hematol. 26, 277 (1998).
30. Yeung, J. H. K., Chu, S. C. S., Effects of sulphydril and non-sulphydril angiotensin converting enzyme inhibitors on mitogen-induced proliferation of mouse splenocytes, Methods Find. Exp. Clin. Pharmacol. 15, 699 (1993).