An experience for ELISA for desmoglein 1, suggesting a possible diagnostic help to determine the initial therapy for pemphigus foliaceus

European Journal of Dermatology

Volumn 10, Issue 1, 2000, Pages 18-21

  Aoyama, Yumi ^a   Tsujimura, Yuki ^a   Funabashi, Miyuki ^a   Sato, Miki ^a   Kamiya, Hideki ^a   Kitajima, Yasuo ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bullous disease; Desmoglein; ELISA; Pemphigus

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; BETAMETHASONE; DESMOGLEIN; DEXAMETHASONE; METHYLPREDNISOLONE; PREDNISOLONE;

ADULT; AGED; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EROSION; ERYTHEMA; FEMALE; HUMAN; IMMUNOBLOTTING; MALE; PEMPHIGUS FOLIACEUS; PEMPHIGUS VULGARIS; SEBORRHEIC DERMATITIS;

ADULT; AGED; AUTOANTIBODIES; AUTOANTIGENS; CADHERINS; DESMOGLEIN 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; METHYLPREDNISOLONE; MIDDLE AGED; MONITORING, PHYSIOLOGIC; PEMPHIGUS; PREDNISOLONE; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX;

EID: 0033953553     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. 1. Eyre RW, Stanley JR. Identification of pemphigus vulgaris antigen extracted from normal human epidermis and comparison with pemphigus foliaceus antigen. J Clin Invest 1988; 81: 807-12.
2. 2. Hashimoto K, Shafran KM, Webber PA, Lazarus GS, Singer KH. Anticell surface pemphigus antibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. J Exp Med 1983; 157: 259-72.
3. 3. Buxton RS, Cowin P, Franke WW, Green KJ, King LA, Koch PJ, Magree AI, Rees DA, Stanley R, Steinberg MS. Nomenclature of desmosomal cadherins. J Cell Biol 1993; 121: 481-3.
4. 4. Koulu L, Kusumi A, Steinberg MS, Klaus-Kovtum V, Stanley JR. Human autoantibodies against a desmosomal core protein in pemphigus foliaceus. J Exp Med 1984; 160: 1509-18.
5. 5. Andrew P, Kowalczyk AP, Anderson JE, Bougwardt JE, Hashimoto T, Stanley JR, Green KJ. Pemphigus sera recognize conformationally sensitive epitopes in the aminoterminal regions of desmoglein-1. J Invest Dermatol 1995; 105: 147-52.
6. 6. Weissman V, Feuerman J, Joshua H, Hazaaz B. The correlation between the antibody titers in sera of patients with pemphigus vulgalis and their clinical state. J Invest Dermatol 1978; 71: 107-9.
7. 7. Judd KP, Lever WF. Correlation of antibodies in skin and serum with disease severity in pemphigus. Arch Dermatol 1979; 115: 428-32.
8. 8. Ishii K, Amagai M, Hall RP, et al. Characterization of autoantibodies in pemphigus using antigen-specific ELISAs with baculovirus expressed recombinant desmogleins. J Immunol 1997; 159: 2010-7.
9. 9. Amagai M. Komai A, Hashimoto T, Shirakata Y, Hashimoto K, Yamada T, Kitajima Y, Ohya K, Iwanami H, Nishikawa T. Usefulness of enzyme-linked immunosorbent assay (ELISA) using recombinant desmogleins 1 and 3 for serodiagnosis of pemphigus. Br J Dermatol 1999 (in press).