Relative efficiency of FISH on metaphase and interphase nuclei from non-mosaic trisomic or triploid fibroblast cultures

Prenatal Diagnosis

Volumn 20, Issue 2, 2000, Pages 159-162

  Ruangvutilert, Pornpimol ^a   Delhanty, Joy D A ^a   Rodeck, Charles H ^a   Harper, Joyce C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

FISH; Interphase nuclei; Metaphase nuclei; Non mosaicism; Triploidy; Trisomy

Indexed keywords

ARTICLE; CELL NUCLEUS; CENTROMERE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME ANALYSIS; CHROMOSOME MOSAICISM; CLINICAL TRIAL; FETUS; FIBROBLAST CULTURE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; INTERPHASE; KARYOTYPE; METAPHASE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; TRIPLOIDY; TRISOMY; X CHROMOSOME; Y CHROMOSOME;

CELL NUCLEUS; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 21; FEMALE; FIBROBLASTS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; MALE; METAPHASE; PLOIDIES; PREGNANCY; PREIMPLANTATION DIAGNOSIS; PRENATAL DIAGNOSIS; SEX CHROMOSOMES; TRISOMY;

EID: 0033953437     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(200002)20:2<159::AID-PD760>3.0.CO;2-2     Document Type: Article

References (14)

1. Bryndorf T, Christensen B, Vad M, Parner J, Carelli MP, Ward BE, Klinger KW, Bang J, Philip J. 1996. Prenatal detection of chromosome aneuploidies in uncultured chorionic villus samples by FISH. Am J Hum Genet 59: 918-926.
2. Bryndorf T, Christensen B, Vad M, Parner J, Brocks V, Philip J. 1997. Prenatal detection of chromosome aneuploidies by fluorescence in situ hybridization: experience with 2000 uncultured amniotic fluid samples in a prospective preclinical trial. Prenat Diagn 17: 333-341.
3. Cacheux V, Tachdjian G, Druart L, Oury JF, Serero S, Blot P, Nessmann C. 1994. Evaluation of X, Y, 18, and 13/21 alpha satellite DNA probes for interphase cytogenetic analysis of uncultured amniocytes by fluorescence in situ hybridization. Prenat Diagn 14: 79-86.
4. Christensen B, Bryndorf T, Philip J, Lundsteen C, Hansen W. 1992. Rapid prenatal diagnosis of trisomy 18 and triploidy in interphase nuclei of uncultured amniocytes by non-radioactive in situ hybridization. Prenat Diagn 12: 241-250.
5. Conn CM, Cozzi J, Harper JC, Winston RM, Delhanty JDA. 1999. Preimplantation genetic diagnosis for couples at high risk of Down syndrome pregnancy owing to parental translocation or mosaicism. J Med Genet 36: 45-50.
6. Delhanty JD, Harper JC, Ao A, Handyside AH, Winston RM. 1997. Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients. Hum Genet 99: 755-760.
7. Gersen SL, Carelli MP, Klinger KW, Ward BE. 1995. Rapid prenatal diagnosis of 14 cases of triploidy using FISH with multiple probes. Prenat Diagn 15: 1-5.
8. Harper JC, Coonen E, Ramaekers FCS, Delhanty JDA, Handyside AH, Winston RML, Hopman AHN. 1994. Identification of the sex of human preimplantation embryos in two hours using an improved spreading method and fluorescent in-situ hybridization (FISH) using directly labelled probes. Hum Reprod 9: 721-724.
9. Harper JC, Coonen E, Handyside AH, Winston RM, Hopman AH, Delhanty JD. 1995. Mosaicism of autosomes and sex chromosomes in morphologically normal, monospermic preimplantation human embryos. Prenat Diagn 15: 41-49.
10. Hook EB. 1977. Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use. Am J Hum Genet 29: 94-97.
11. Munne S, Marquez C, Magli C, Morton P, Morrison L. 1998. Scoring criteria for preimplantation genetic diagnosis of numerical abnormalities for chromosomes X, Y, 13, 16, 18 and 21. Molec Hum Reprod 4: 863-870.
12. van Opstal D, van Hemel JO, Eussen BH, van der Heide A, van den Berg C, In'T Veld PA, Los FJ. 1995. A chromosome 21-specific cosmid cocktail for the detection of chromosome 21 aberrations in interphase nuclei. Prenat Diagn 15: 705-711.
13. Winsor EJ, Silver MP, Theve R, Wright M, Ward BE. 1996. Maternal cell contamination in uncultured amniotic fluid. Prenat Diagn 16: 49-54.
14. Zheng YL, Ferguson-Smith MA, Warner JP, Ferguson-Smith ME, Sargent CA, Carter NP. 1992. Analysis of chromosome 21 copy number in uncultured amniocytes by fluorescence in situ hybridization using a cosmid contig. Prenat Diagn 12: 931-943.