Artefact formation in the determination of residual solvents according to a method of the European Pharmacopeia

International Journal of Pharmaceutics

Volumn 195, Issue 1-2, 2000, Pages 159-169

  Lee, C R ^a   Nguyen Van Dau, C ^a   Krstulovic A M ^a  

^a SANOFI   (France)

Author keywords

Diltiazem; GC headspace analysis; Pharmacopeial method

Indexed keywords

ALKYLATING AGENT; DIETHYLAMINE; DILTIAZEM; DIMETHYLAMINE; ETHER; HYDROCHLORIC ACID; HYPOCHLORITE SODIUM; N,N DIMETHYLFORMAMIDE; REAGENT; SOLVENT; SUCCINIMIDE DERIVATIVE;

ARTICLE; ARTIFACT; DRUG HYDROLYSIS; DRUG IMPURITY; DRUG SOLUBILITY; EUROPE; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICAL LITERATURE; PRIORITY JOURNAL; VOLATILIZATION;

CALCIUM CHANNEL BLOCKERS; DILTIAZEM; DIMETHYLAMINES; DIMETHYLFORMAMIDE; DRUG CONTAMINATION; EUROPE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROCARBONS, CHLORINATED; MOLECULAR STRUCTURE; PHARMACOPOEIAS; SOLVENTS;

EID: 0033951526     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00386-5     Document Type: Article

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