LMCE3 treatment strategy: Results in 99 consecutively diagnosed stage 4 neuroblastomas in children older than I year at diagnosis

Journal of Clinical Oncology

Volumn 18, Issue 3, 2000, Pages 468-476

  Frappaz, D ^a   Michon, J ^a   Coze, C ^a   Berger, C ^a   Plouvier, E ^a   Lasset, C ^a   Bernard, J L ^a   Stephan, J L ^a   Bouffet, E ^a   Buclon, M ^a   Combaret, V ^a   Fourquet, A ^a   Philip, T ^a   Zucker, J M ^a  

^a UNIVERSITY HOSPITAL OF BESANÇON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CISPLATIN; CREATININE; CYCLOPHOSPHAMIDE; DOPAMINE; DOXORUBICIN; ETOPOSIDE; FERRITIN; HOMOVANILLIC ACID; LACTATE DEHYDROGENASE; MELPHALAN; NEURON SPECIFIC ENOLASE; VANILMANDELIC ACID; VINCRISTINE;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER STAGING; CHILD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROBLASTOMA; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; SURVIVAL RATE; TREATMENT OUTCOME; WHOLE BODY RADIATION;

EID: 0033950139     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.2000.18.3.468     Document Type: Article

References (49)

1. Hartmann O, Scopinaro M, Tournade MF, et al: Neuroblastomes traités à l'Institut Gustave Roussy de 1979 à 1979: Cent soixante treize cas. Arch Fr Ped 40:15-21, 1983
2. Berthold F, Sahin K, Hero B, et al: The current contribution of molecular factors to risk estimation in neuroblastoma patients. Eur J Cancer 33:2092-2097, 1997
3. Philip T: Overview of current treatment of neuroblastoma. Am J Hematol Oncol 14:97-102, 1992
4. Philip T, Bernard JL, Zucker JM, et al: High dose chemotherapy with bone marrow transplantation as consolidation treatment in neuroblastoma: An unselected group of stage IV patients over one year of age. J Clin Oncol 5:266-271, 1987
5. Philip T, Zucker JM, Bernard JL, et al: Improved survival at 2 and 5 years in the LMCE1 unselected group of 72 children with stage IV neuroblastoma older than 1 year of age at diagnosis: Is cure possible in a small subgroup? J Clin Oncol 9:1037-1044, 1991
6. Ladenstein R, Lasset C, Hartmann O, et al: Impact of megatherapy on survival after relapse from stage 4 neuroblastoma in patients over 1 year of age at diagnosis: A report from the European Group for Bone Marrow Transplantation. J Clin Oncol 11:2330-2341, 1993
7. Coze C, Hartmann O, Michon J, et al: NB87 induction protocol for stage 4 neuroblastoma in children over 1 year of age: A report from the French Society of Pediatric Oncology. J Clin Oncol 12:3433-3440, 1997
8. Philip T, Ladenstein R, Zucker JM, et al: Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: The LMCE2 study. Br J Cancer 67:119-127, 1993
9. Frappaz D, Michon J, Hartmann O, et al: VP16-carboplatin in neuroblastoma: A SFOP phase II study. J Clin Oncol 10:1592-1601, 1992
10. Zucker JM, Philip T, Bernard JL, et al: Single or double consolidation treatment according to remission status after initial therapy in metastatic neuroblastoma: First results of LMCE3 study in 40 patients, in Evans AE, D'Angio GJ, Knudson AG, et al (eds): Advances in Neuroblastoma Research 3. New York, NY, Wiley Liss Inc, 1991, pp 543-551
11. Brodeur GM, Pritchard J, Berthold F, et al: Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 11:1466-1477, 1993
12. Favrot MC, Frappaz D, Maritaz O, et al: Histological, cytological and immunological analyses are complementary for the detection of neuroblastoma cells in the bone marrow. Br J Cancer 54:637-641, 1986
13. World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment. Geneva, Switzerland, World Health Organization, WHO Offset Publication 48, 1979
14. Combaret V, Favrot MC, Chauvin F, et al: Immunomagnetic depletion of malignant cells from autologous bone marrow graft: From experimental models to clinical trials. J Immunogenet 16:125-136, 1989
15. Bernard JL, Philip T, Zucker JM, et al: Sequential cisplatin/VM 26 and vincristine/cyclophosphamide/doxorubicin in metastatic neuroblastoma: An effective non cross resistant regimen? J Clin Oncol 5:1952-1959, 1987
16. Shafford EA, Rogers DW, Pritchard J: Advanced neuroblastoma: Improved response rate using multidrug regimen (OPEC) including sequential cis platinum and VM 26. J Clin Oncol 2:742-747, 1984
17. Kushner BH, Laquaglia MP, Bonilla MA, et al: Highly effective induction therapy for stage 4 neuroblastoma in children over 1 year of age. J Clin Oncol 12:2607-2613, 1994
18. Graham Pole J, Casper J, Elfenbein G, et al: High-dose chemoradiotherapy supported by marrow infusions for advanced neuroblastoma: A Pediatric Oncology Group study. J Clin Oncol 9:152-158, 1991
19. Stram DO, Matthay KK, O'Leary M, et al: Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: A report of two concurrent Children's Cancer Group studies. J Clin Oncol 14:2417-2426, 1996
20. Kletzel M, Abella EM, Sandier ES, et al: Thiotepa and cyclophosphamide with stem cell rescue for consolidation therapy for children with high-risk neuroblastoma: A phase I/II study of the Pediatric Blood and Marrow Transplant Consortium. J Pediatr Hematol Oncol 20:49-54, 1998
21. Pinkerton CR: Where next with therapy in advanced neuroblastoma? Br J Cancer 61:351-353, 1990
22. Dini G, Lanino E, Garaventa A, et al: Myeloablative therapy and unpurged bone marrow transplantation for poor prognosis neuroblastoma: Report of 34 cases. J Clin Oncol 9:962-969, 1991
23. Kushner BH, O'Reilly RJ, Mandell LR, et al: Myeloablative combination chemotherapy without total body irradiation for neuroblastoma. J Clin Oncol 9:274-279, 1991
24. Kremens B, Klingebiel T, Hermann F, et al: High-dose consolidation with local radiation and bone marrow rescue in patients with advanced neuroblastoma. Med Pediatr Oncol 23:470-475, 1994
25. Ohuma N, Takahashi H, Kaneko M, et al: Treatment combined with bone marrow transplantation for advanced neuroblastoma: An analysis of patients who were pretreated intensively with the protocol of the Study Group of Japan. Med Pediatr Oncol 24:181-187, 1995
26. Hartmann O, Benhamou E, Beaujean F, et al: Repeated high-dose chemotherapy followed by purged autologous bone marrow transplantation as consolidation therapy in metastatic neuroblastoma. J Clin Oncol 5:1205-1211, 1987
27. Corbett R, Pinkerton R, Pritchard J, et al: Pilot study of high-dose vincristine, etoposide, carboplatin and melphalan with autologous bone marrow rescue in advanced neuroblastoma. Eur J Cancer 28A: 1324-1328, 1992
28. Gordon SJ, Pearson AD, Reid MM, et al: Toxicity of single-day high-dose vincristine, melphalan, etoposide and carboplatin consolidation with autologous bone marrow rescue in advanced neuroblastoma. Eur J Cancer 28A:1319-1323, 1992
29. Lam-Po-Tang PR, McCowage GB, Vowels MR: Teniposide, doxorubicin, melphalan, cisplatin, and total body irradiation with autologous bone marrow transplantation for advanced neuroblastoma. Transplant Proc 25:2881-2882, 1993
30. Santana VM, Schell MJ, Williams R, et al: Escalating sequential high-dose carboplatin and etoposide with autologous marrow support in children with relapsed solid tumors. Bone Marrow Transplant 10:457-456, 1992
31. Matthay KK, Harris R, Reynolds CP, et al: Improved event-free survival for autologous bone marrow transplantation vs chemotherapy in neuroblastoma: A phase III randomized Children's Cancer Group study. Proc Am Soc Clin Oncol 17:525a, 1998 (abstr 2018)
32. Frei E III, Teicher BA, Holden S, et al: Preclinical studies and clinical correlations of the effect of alkylating dose. Cancer Res 48:6417-6423, 1988
33. Pinkerton CR: ENSG 1-randomised study of high-dose melphalan in neuroblastoma. Bone Marrow Transplant 7:112-113, 1991
34. Rill DR, Santana VM, Roberts WM, et al: Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood 84:380-383, 1994
35. Glorieux P, Bouffet E, Philip I, et al: Metastatic interstitial pneumonitis after autologous bone marrow transplantation. Cancer 58:2136-2139, 1986
36. Frappaz D, Bouffet E, Thiesse P, et al: Isolated epidural relapse of neuroblastoma after autologous bone marrow transplantation. Pediatr Hematol Oncol 11:439-443, 1994
37. Garaventa A, Ladenstein R, Chauvin F, et al: High-dose chemotherapy with autologous bone marrow rescue in advanced stage IV neuroblastoma. Eur J Cancer 29A:487-491, 1993
38. Matthay KK, Seeger RC, Reynolds CP, et al: Allogeneic versus autologous purged bone marrow transplantation for neuroblastoma: A report from the Children's Cancer Group. J Clin Oncol 12:2382-2389, 1994
39. Ladenstein R, Lasset C, Hartmann O, et al: Comparison of auto versus allografting as consolidation of primary treatments in advanced neuroblastoma over one year of age at diagnosis: Report from the European Group for Bone Marrow Transplantation. Bone Marrow Transplant 14:37-46, 1994
40. Shorter NA, Davidoff AM, Evans AE, et al: The role of surgery in the management of stage IV neuroblastoma: A single institution study. Med Pediatr Oncol 24:287-291, 1995
41. Matthay KK, Atkinson JB, Stram DO, et al: Patterns of relapse after autologous purged bone marrow transplantation for neuroblastoma: A Children's Cancer Group pilot study. J Clin Oncol 11:2226-2233, 1993
42. Ikeda H, August CS, Goldwein JW, et al: Sites of relapse in patients with neuroblastoma following bone marrow transplantation in relation to preparatory "debulking" treatments. J Pediatr Surg 27:1438-1441, 1992
43. Ladenstein R, Lasset C, Hartmann O, et al: Impact of megatherapy on survival after relapse from stage 4 neuroblastoma in patients over 1 year of age at diagnosis: A report from the European Group for Bone Marrow Transplantation. J Clin Oncol 11:2330-2341, 1993
44. Berthold F, Kassenbohmer R, Zieschang J: Multivariate evaluation of prognostic factors in localized neuroblastoma. Am J Pediatr Hematol Oncol 16:107-115, 1994
45. Combaret V, Lasset C, Frappaz D, et al: Evaluation of CD 44 prognostic value in neuroblastoma: Comparison with the other prognostic factors. Eur J Cancer 31A:545-548, 1995
46. Stram DO, Matthay KK, O'Leary M, et al: Myeloablative chemoradiotherapy versus continued chemotherapy for high risk neuroblastoma, in Proceedings of Advances in Neuroblastoma Research No. 6, May 1993, Philadelphia, PA (abstr 133)
47. Carrie C, Artiges V, Fourquet A, et al: Late sequelae in children treated with high dose chemotherapy, TBI and ABMT for metastatic neuroblastoma: Growth, endocrine and school disorder. Med Pediatr Oncol 31:232, 1998
48. Favrot MC, Michon J, Floret D, et al: IL 2 immunotherapy in children with neuroblastoma after high dose chemotherapy and autologous bone marrow transplantation. Pediatr Hematatol Oncol 7:275-284, 1990
49. Reynolds CP, Villablanca JG, Stram DO, et al: 13-Cis-retinoic acid after intensive consolidation therapy for neuroblastoma improves event-free survival: A randomized Childrens Cancer Group (CCG) study. Proc Am Soc Clin Oncol 17:2a, 1998 (abstr 5)