Cloacal and urogenital malformations in adriamycin-exposed rat fetuses

BJU International

Volumn 86, Issue 1, 2000, Pages 107-112

  Liu, M I P ^a   Hutson, J M ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Adriamycin; Animal model; Bladder agenesis; Cloacal; Urogenital; VATER

Indexed keywords

DOXORUBICIN;

AGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER MALFORMATION; CLOACA; FEMALE; FETUS; HYDRONEPHROSIS; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; TERATOGENESIS; UROGENITAL TRACT MALFORMATION;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANTINEOPLASTIC AGENTS; CLOACA; DOXORUBICIN; FEMALE; MALE; MICROSCOPY, ELECTRON; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; UROGENITAL ABNORMALITIES;

EID: 0033948020     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.2000.00706.x     Document Type: Article

References (28)

1. 1 Beasley SW, Phelan E, Kelly JH, Myers NA, Chetcuti P, Auldist AW. Urinary tract abnormalities in association with oesophageal atresia: frequency, significance, influence on management. Pediatr Surg Int 1992; 7: 94-6
2. 2 Berdon WE, Hochberg B, Baker DH, Grossman H, Santulli TV. The association of lumbosacral genitourinary anomalies with imperforate anus. Am J Roentgen 1966; 98: 181-91
3. 3 Metts JC III, Kotkin L, Kasper S, Shyr Y, Adams MC, Brock JW III. Genital malformations and coexistent urinary tract or spinal anomalies in patients with imperforate anus. J Urol 1997; 158: 1298-300
4. 4 Quan L, Smith DW. The VATER association: Vertebral defects, anal atresia, T-E fistula with esophageal atresia, radial and renal dysplasia: a spectrum of associated defects. J Pediatr 1973; 82: 104-7
5. 5 Temtamy SA, Miller JD. Extending the scope of the VATER association: Definition of the VATER syndrome. J Pediatr 1974; 85: 345-9
6. 6 Nora AH, Nora JJ. A syndrome of multiple congenital anomalies associated with teratogenic exposure. Arch Environ Health 1975; 30: 17-21
7. 7 Baumann W, Greinacher I, Emmrich P, Spranger J. VATER order VACTERL [German]. Klin Padiatr 1976; 188: 328-37
8. 8 Thompson DJ, Molello JA, Strebig RJ, Dyke IL. Teratogenicity of adriamycin and daunorubicin in the rat and rabbit. Teratology 1978; 17: 151-8
9. 9 Diez-Pardo JA, Qi B, Navarro C, Tovar JA. A new rodent experimental model of esophageal atresia and tracheoesophageal fistula: Preliminary report. J Ped Surg 1996; 31: 498-502
10. 10 Qi BQ, Merei J, Farmer P et al. Cardiovascular malformations in rat fetuses with oesophageal atresia and tracheooesophageal fistula induced by adriamycin. Pediatr Surg Int 1997; 12: 556-64
11. 11 Kotsios C, Merei J, Hutson JM, Graham HK. Skeletal anomalies in the adriamycin-exposed prenatal rat: a model for VATER association. J Orth Res 1998; 16: 50-3
12. 12 Duhamel B. From the mermaid to anal imperforation: The syndrome of caudal regression. Arch Dis Child 1961; 36: 152-5
13. 13 Alles AJ, Sulik KK. A review of caudal dysgenesis and its pathogenesis as illustrated in an animal model. Birth Defects 1993; 29: 83-102
14. 14 Khoury MJ, Cordero JF, Greenberg F, James LM, Erickson JD. A population study of the VACTERL association: Evidence for its etiologic heterogeneity. Pediatrics 1983; 71: 815-20
15. 15 Czeizel A, Ludanyi I. An aetiological study of the VACTERL association. Eur J Pediatr 1985; 144: 331-7
16. 16 Weaver DD, Mapstone CL, Yu PL. The VATER association. Analysis of 46 patients. Am J Dis Child 1986; 140: 225-9
17. 17 Uehling DT, Gilbert E, Chesney R. Urologic implications of the VATER association. J Urol 1983; 129: 352-4
18. 18 Dusmet M, Fete F, Crusi A, Cox JN. VATER association: report of a case with three unreported malformations. J Med Genet 1988; 25: 57-60
19. 19 Sofatzis JA, Alexacos L, Skouteli HN, Tiniakos G, Padiatellis C. Malformed female genitalia in newborns with the VATER association. Acta Paediatr Scand 1983; 72: 923-4
20. 20 Miller HL. Agenesia of the urinary bladder and urethra. J Urol 1948; 59: 1156-63
21. 21 Akdas A, Iseri C, Ozgur S, Kirkali Z. Bladder agenesis. Int Urol Nephrol 1988; 20: 261-3
22. 22 Stephens FD, Smith ED, Hutson JM. Congenital Anomalies of the Urinary and Genital Tracts Oxford: Isis Medical Media Ltd 1996: 4-7, 400-4
23. 23 Moore KL. The Developing Human, 4th edn. Philadelphia: WB Saunders, 1988: 257-8
24. 24 Patten BM. Human Embryology, 2nd edn. New York: McGraw-Hill 1947
25. 25 Di Marco A, Gaetani M, Scarpinato B. Adriamycin (NSC-123,127): a new antibiotic with antitumour activity. Cancer Chemother Rep 1969; 53: 33-7
26. 26 Skladanowski A, Konopa J. Adriamycin and daunorubicin induce programmed cell death (apoptosis) in tumour cells. Biochem Pharmacol 1993; 46: 375-82
27. 27 Ling YH, Priebe W, Perez-Soler R. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res 1993; 53: 1845-52
28. 28 Tobias JS, Bloom HJ. Doxorubicin in pregnancy [letter]. Lancet 1980; 1: 776