메뉴 건너뛰기




Volumn 61, Issue 1, 2000, Pages 14-21

Differences in efficacy and NA+ sensitivity between α(2B) and α(2D) adrenergic receptors: Implications for R and R* states

Author keywords

Allosteric modulation; Alpha 2 adrenergic receptors; Constitutive receptor activity; Epinephrine; G protein; GTP binding assay; Sodium ions

Indexed keywords

ALPHA 2B ADRENERGIC RECEPTOR; ALPHA 2D ADRENERGIC RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; SODIUM ION;

EID: 0033947910     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028375     Document Type: Article
Times cited : (5)

References (21)
  • 2
    • 0028176054 scopus 로고
    • 2D adrenergic receptor activation of G proteins: Evidence for a precoupled R/G state
    • 2D adrenergic receptor activation of G proteins: Evidence for a precoupled R/G state. Mol Pharmacol 1994;45:524-531.
    • (1994) Mol Pharmacol , vol.45 , pp. 524-531
    • Tian, W.-N.1    Lanier, S.M.2    Duzic, E.3    Deth, R.C.4
  • 3
    • 0025238655 scopus 로고
    • Spontaneous association between opioid receptors and GTT-binding regulatory proteins in native membranes: Specific regulation by antagonists and sodium ions
    • Costa T, Lang J, Gless C, Herz A: Spontaneous association between opioid receptors and GTT-binding regulatory proteins in native membranes: Specific regulation by antagonists and sodium ions. Mol Pharmacol 1990;37: 383-394.
    • (1990) Mol Pharmacol , vol.37 , pp. 383-394
    • Costa, T.1    Lang, J.2    Gless, C.3    Herz, A.4
  • 4
    • 0020510699 scopus 로고
    • + eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin
    • + eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin. J Biol Chem 1983;258:3907-3912.
    • (1983) J Biol Chem , vol.258 , pp. 3907-3912
    • Connolly, T.M.1    Limbird, L.E.2
  • 5
    • 0020603182 scopus 로고
    • 2-adrenergic receptor system of human platelets
    • 2-adrenergic receptor system of human platelets. J Biol Chem 1983;258:3913-3919.
    • (1983) J Biol Chem , vol.258 , pp. 3913-3919
    • Motulsky, H.J.1    Insel, P.A.2
  • 7
    • 0020046398 scopus 로고
    • 2-adrenergic receptor in membrane and solubilized preparations
    • 2-adrenergic receptor in membrane and solubilized preparations. Mol Pharmacol 1982;21:609-617.
    • (1982) Mol Pharmacol , vol.21 , pp. 609-617
    • Limbird, L.E.1    Speck, J.L.2    Smith, S.K.3
  • 8
    • 0026608113 scopus 로고
    • Drug efficacy at guanine nucleolide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and receptor activity in the absence of ligand
    • Costa T, Ogino Y, Munson PJ, Onaran HO, Rodbard D: Drug efficacy at guanine nucleolide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and receptor activity in the absence of ligand. Mol Pharmacol 1992;41: 549-560.
    • (1992) Mol Pharmacol , vol.41 , pp. 549-560
    • Costa, T.1    Ogino, Y.2    Munson, P.J.3    Onaran, H.O.4    Rodbard, D.5
  • 10
    • 0024410591 scopus 로고
    • 2-adrenergic receptor in Chinese hamster ovary cells: Evidence for indepedent pathways of receptor coupling to adenylate cyclase attenuation and activation
    • 2-adrenergic receptor in Chinese hamster ovary cells: Evidence for indepedent pathways of receptor coupling to adenylate cyclase attenuation and activation. J Biol Chem 1989;264:11754-11761.
    • (1989) J Biol Chem , vol.264 , pp. 11754-11761
    • Fraser, C.M.1    Arakawa, S.2    McCombie, W.R.3    Venter, J.C.4
  • 11
    • 0026011644 scopus 로고
    • 2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms
    • 2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms. Mol Pharmacol 1991;39: 239-245.
    • (1991) Mol Pharmacol , vol.39 , pp. 239-245
    • Jones, S.B.1    Halenda, S.P.2    Bylund, D.B.3
  • 12
    • 0342400917 scopus 로고
    • 2-adrenergic receptor subtypes in a cell-type specific manner
    • 2-adrenergic receptor subtypes in a cell-type specific manner. J Biol Chem 1992;267:24025-24052.
    • (1992) J Biol Chem , vol.267 , pp. 24025-24052
    • Duzic, E.1    Lanier, S.M.2
  • 15
    • 0029067834 scopus 로고
    • Factors determining specificity of signal transduction by G-protein-coupled receptors: Regulation of signal transfer from receptor to G-protein
    • Sato M, Kataoka R, Dingus J, Wilcox M, Hildebrande JD, Lanier SM: Factors determining specificity of signal transduction by G-protein-coupled receptors: Regulation of signal transfer from receptor to G-protein. J Biol Chem 1995; 270:15269-15276.
    • (1995) J Biol Chem , vol.270 , pp. 15269-15276
    • Sato, M.1    Kataoka, R.2    Dingus, J.3    Wilcox, M.4    Hildebrande, J.D.5    Lanier, S.M.6
  • 17
    • 0343626035 scopus 로고
    • Receptor-stimulated GTPase activity of G-proteins
    • Houslay MD, Milligan G (eds): Chichester, Wiley
    • Gierschik P, Jakobs KH: Receptor-stimulated GTPase activity of G-proteins; in Houslay MD, Milligan G (eds): Molecular Pharmacology of Cell Regulation. Chichester, Wiley, 1990, vol 1, pp 67-82.
    • (1990) Molecular Pharmacology of Cell Regulation , vol.1 , pp. 67-82
    • Gierschik, P.1    Jakobs, K.H.2
  • 19
    • 0025863465 scopus 로고
    • Pivotal role for asparate-80 in the regulation of dopamine D2 receptor affinity for drugs and inhibition of adenylylcyclase
    • Neve KA, Cox BA, Hennigsen RA, Spanoyannis A, Neve RL: Pivotal role for asparate-80 in the regulation of dopamine D2 receptor affinity for drugs and inhibition of adenylylcyclase. Mol Pharmacol 1991;39:733-739.
    • (1991) Mol Pharmacol , vol.39 , pp. 733-739
    • Neve, K.A.1    Cox, B.A.2    Hennigsen, R.A.3    Spanoyannis, A.4    Neve, R.L.5
  • 20
    • 0027986462 scopus 로고
    • 2-adrenergic receptor-G-protein interactions
    • 2-adrenergic receptor-G-protein interactions. J Biol Chem 1994;269:29557-29564.
    • (1994) J Biol Chem , vol.269 , pp. 29557-29564
    • Ceresa, B.1    Limbird, L.E.2
  • 21
    • 0025248152 scopus 로고
    • +, 5′-guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: Evidence for receptor G-protein precoupling
    • +, 5′-guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: Evidence for receptor G-protein precoupling. J Pharmacol Exp Ther 1990;252:1184-1196.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 1184-1196
    • Jagadeesh, G.1    Cragoe, E.J.2    Deth, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.