Dose response and safety of cizolirtine citrate (E-4018) in patients with pain following extraction of third molars

Current Medical Research and Opinion

Volumn 16, Issue 2, 2000, Pages 107-114

  Matthew, I R ^a   Ogden, G R ^b   Frame, J W ^c   Wight, A J ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Acetaminophen; Cizolirtine citrate; Pain, postoperative; Surgery, oral

Indexed keywords

ANALGESIC AGENT; CIZOLIRTINE; PARACETAMOL; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLAR TOOTH; NAUSEA; RANDOMIZED CONTROLLED TRIAL; SELF EVALUATION; TOOTH EXTRACTION; TOOTH PAIN; VOMITING;

EID: 0033945938     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/0300799009117014     Document Type: Article

References (12)

1. Meechan, J. G. and Seymour, R. A. (1993). The use of third molar surgery in clinical pharmacology. Br. J. Oral Maxillofac. Surg., 31, 360-365.
2. Hutchison, G. L., Crofts, S. L. and Gray, I. G. (1990). Preoperative piroxicam for postoperative analgesia in dental surgery. Br. J. Anaesth., 65, 500-503.
3. Wilson, I. H., Richmond, M. N. and Strike, P. W. (1986). Regional analgesia with bupivacaine in dental anaesthesia. Br. J. Anaesth., 58, 401-405.
4. Seymour, R. A., Ward-Booth, P. and Kelly, P. J. (1996). Evaluation of different doses of soluble ibuprofen and ibuprofen tablets in postoperative dental pain. Br. J. Oral Maxillofac. Surg., 34, 110-114.
5. Walton, G. M., Rood, J. P., Snowdon, A. T. and Rickwood, D. (1993). Ketorolacand diclofenac for postoperative pain relief following oral surgery. Br. J Oral Maxillofac. Surg. 31, 158-160.
6. Sisk, A. L. and Grover, B. J. (1990). A comparison of preoperative and postoperative naproxen sodium for suppression of postoperative pain. J. Oral Maxillofac. Surg. 48, 674-678.
7. Savin, J. and Ogden, G. R. (1997). Third molar surgery - a preliminary report on aspects affecting quality of life in the early postoperative period. Br J. Oral Maxillofac. Surg. 35, 246-253.
8. Caturla, M. C., Salomo, J., Soler, M., Martinez, I. and Roser, R. (1991). Validation of GC method to measure a new analgesic (E-4018) in biological samples. Comparison between HPLC and GC method. J. Pharm. Biomed. Anal., 9, 1181-1184.
9. Torrens, A., Castrillo, J. A., Frigola, J., Salgado, L. and Redondo, J. (1999). Optical resolution and enantiomeric purity determination of the analgesic Cizolirtine. Chirality, 11, 63-69.
10. Oikarinen, K. (1991). Postoperative pain after mandibular third-molar surgery. Acta Odontol. Scand., 49, 7-13.
11. Berge, T. I. (1988). Visual analogue scale assessment of postoperative swelling. A study of clinical inflammatory variables subsequent to third-molar surgery. Acta Odontol. Scand., 46, 233-240.
12. Seymour, R. A., Meechan, J. G. and Blair, G. S. (1985). An investigation into post-operative pain after third molar surgery under local analgesia. Br. J. Oral Maxillofac. Surg. 23, 410-418.