Identification of high-risk breast cancer patients from genetic changes of their tumors

Surgery Today

Volumn 30, Issue 6, 2000, Pages 516-522

  Watatani, Masahiro ^a   Inui, Hiroki ^a   Nagayama, Koichi ^a   Imanishi, Yukihito ^a   Nishimura, Keisuke ^a   Hashimoto, Yukihiko ^a   Yamauchi, Eiju ^a   Hojo, Toshiya ^a   Kotsuma, Yoshikazu ^b   Yamato, Munehisa ^a   Matsunami, Nobuteru ^a   Yasutomi, Masayuki ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Kotsuma Clinic   (Japan)

Author keywords

Amplification; Breast cancer; Genetic changes; Loss of heterozygosity; Prognostic factor

Indexed keywords

ARTICLE; BREAST CANCER; CANCER RISK; CHROMOSOME 11P; CHROMOSOME 16Q; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME 18Q; GENE AMPLIFICATION; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY;

EID: 0033945844     PISSN: 09411291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005950070118     Document Type: Article

References (39)

1. 1. Deng G, Lu Y, Zlotnikov G, Thor AD, Smith HS (1996) Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 274:2057-2059
2. 2. Devilee P, Van den Broek M, Kuipers-Dijkshoorn N, Kolluri R, Khan PM, Pearson PL, Cornelisse CJ (1989) At least four different chromosomal regions are involved in loss of heterozygosity in human breast cancer. Genomics 5:554-560
3. 3. Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelotype of breast cancer: cumulative allele losses promote tumor progressin in primary breast cancer. Cancer Res 50:7184-7189
4. 4. Andersen TI, Gaustad A, Ottestad L, Farrants GW, Nesland JM, Tveit KM, Borresen AL (1992) Genetic alterations of the tumor suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas. Genes Chrom Cancer 4:113-121
5. 5. Driouch K, Briffod M, Bieche I, Champeme MH, Lidereau R (1998) Location of several putative genes possibly involved in human breast cancer progression. Cancer Res 58:2081-2086
6. 6. Berns EMJJ, Klijn JGM, Putten WLJ, Staveren IL, Portengen H, Foekens JA (1992) c-myc amplification is a better prognostic factor than Her2/neu amplification in primary breast cancer. Cancer Res 52:1107-1113
7. 7. Lonn U, Lonn S, Nilsson B, Stenkvist B (1995) Prognostic value of erb-B2 and myc amplification in breast cancer imprints. Cancer 75:2681-2687
8. 8. Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neuoncogene. Science 235:177-182
9. 9. Tsuda H, Hirohashi S, Shimosato Y, Hirota T, Tsugane S, Yamamoto H, Miyajima N, Toyoshima K, Yamamoto T, Yokota J, Yoshida T, Sakamoto H, Terada M, Sugimura T (1989) Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/INT2 and c-erbB-2/ear-1. Cancer Res 49:3104-3108
10. 10. Genuardi M, Tsihira H, Anderson DE, Saunders GF (1989) Distal deletion of chromosome 1p in ductal carcinoma of the breast. Am J Hum Genet 45:73-82
11. 11. Chen LC, Dollbaum C, Smith HS (1989) Loss of heterozygosity on chromosome 1q in human breast cancer. Proc Natl Acad Sci USA 86:7204-7207
12. 12. Ali IU, Lidereau R, Theillet C, Callahan R (1987) Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 238:185-188
13. 13. Sato T, Akiyama F, Sakamoto G, Kasumi F, Nakamura Y (1991) Accumulation of genetic alterations and progression of primary breast cancer. Cancer Res 51:5794-5799
14. 14. Lindblom A, Rotstein S, Skoog L, Nordenskjold M, Larsson C (1993) Deletions on chromosome 16 in primary familial breast carcinomas are associated with development of distant metastases. Cancer Res 53:3707-3711
15. 15. Mackay J, Steel CM, Elder PA, Forrest APM, Evans HJ (1988) Allele loss on short arm of chromosome 17 breast cancer. Lancet 2:1384-1385
16. 16. Cropp CS, Lidereau R, Campbell G, Champene MH, Callahan R (1990) Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified. Proc Natl Acad Sci USA 87:7737-7741
17. 17. Takita K, Sato T, Miyagi M, Watatani M, Akiyama F, Sakamoto G, Kasumi F, Abe R, Nakamura Y (1992) Correlation of loss of alleles on the short arms of chromosomes 11 and 17 with metastasis of primary breast cancer to lymph nodes. Cancer Res 52:3914-3917
18. 18. Nagayama K, Watatani M (1993) Analysis of genetic alterations related to the development and progression of breast carcinoma. Jpn J Cancer Res 84:1159-1164
19. 19. Harada Y, Katagiri T, Ito I, Akiyama F, Sakamoto G, Kasumi F, Nakamura Y, Emi M (1994) Genetic studies of 457 breast cancers. Cancer 74:2281-2286
20. 20. Kerangueven F, Noguchi T, Coulier F, Allione F, Wargniez V, Simony-Lafontaine J, Longy M, Jacquemier J, Sobol H, Eisinger F, Birnbaum D (1997) Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas. Cancer Res 57:5469-5474
21. 21. Watatani M, Nagayama K, Imanishi Y, Kurooka K, Wada T, Inui H, Hirai K, Ozaki M, Yasutomi M (1993) Genetic alterations on chromosome 17 in human breast cancer: relationship to clinical features and DNA ploidy. Breast Cancer Res Treat 28:231-239
22. 22. Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B, King MC (1990) Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250:1684-1689
23. 23. Varesco L, Caligo MA, Simi P, Black DM, Nardini V, Casarino L, Rocchi M, Ferrara G, Solomon E, Bevilacqua G (1992) The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with Bg1II. Genes Chrom Cancer 4:84-88
24. 24. Tsukamoto K, Ito N, Yoshimoto M, Kasumi F, Akiyama F, Sakamoto G, Nakamura Y, Emi M (1998) Allelic loss on chromosome 1p is associated with progression and lymph node metastasis of primary breast carcinoma. Cancer 82:317-322
25. 25. Minobe K, Onda M, Iida A, Kasumi F, Sakamoto G, Nakamura Y, Emi M (1998) Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer. Jpn J Cancer Res 89:916-922
26. 26. Nagai MA, Medeiros AC, Brentani MM, Brentani RR, Marques LA, Mazoyer S, Mulligan LM (1995) Five distinct deleted regions on chromosome 17 defining different subsets of human primary breast tumors. Oncology 52:448-453
27. 27. Cropp CS, Champeme MH, Lidereau R, Callahan R (1993) Identification of three regions on chromosome 17q in primary human breast carcinomas which are frequently deleted. Cancer Res 53:5617-5619
28. 28. Callahan R (1998) Somatic mutations that contribute to breast cancer. Biochem Soc Symp 63:211-221
29. 29. Phelan CM, Borg A, Cuny M, Crichton DN, Baldersson T, Andersen TI, Caligo MA, Lidereau R, Lindblom A, Seitz S, Kelsell D, Hamann U, Rio P, Thorlacius S, Papp J, Olah E, Ponder B, Bignon YJ, Scherneck S, Barkardottir R, Borresen DA, Eyfjord J, Theillet C, Thompson AM, Larsson C (1998) Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters. Cancer Res 58:1004-1012
30. 30. Studzinski GP, Godyn JJ (1995) The genetic basis for emergence and progression of breast cancer. In: Donegan WL, Spratt JS (eds) Cancer of the breast. Saunders, Philadelphia, pp 309-316
31. 31. Borg A, Sigurdsson H, Clark GM, Ferno M, Fuqua SA, Olsson H, Killander D, McGurie WL (1991) Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis. Br J Cancer 63:136-142
32. 32. Champeme MH, Bieche I, Hacene K, Lidereau R (1994) INT2/ FGF3 amplification is a better independent predictor of relapse than c-myc and c-erbB-2/neu amplification in primary human breast cancer. Mod Pathol 7:900-905
33. 33. Pauley RJ, Gimotty PA, Paine TJ, Dawson PJ, Wolman SR (1996) INT2 and ERBB2 amplification and ERBB2 expression in breast tumors from patients with different outcomes. Breast Cancer Res Treat 37:65-76
34. 34. Fioravanti L, Cappelletti V, Coradini D, Miodini P, Borsani G, Daidone MG, Di Fronzo G (1997) INT2 oncogene amplification and prognosis in node-negative breast carcinoma. Int J Cancer 74:620-624
35. 35. Tsuda H, Sakamaki C, Tsugane S, Fukutomi T, Hirohashi S (1998) A prospective study of the significance of gene and chromosome alterations as prognostic indicators of breast cancer patients with lymph node metastases. Breast Cancer Res Treat 48:21-32
36. 36. Schuuring E, Verhoeven E, Mooi WJ, Michalides RJ (1992) Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 7:355-361
37. 37. Hui R, Campbell DH, Lee CS, McCaul K, Horsfall DJ, Musgrove EA, Daly RJ, Seshadri R, Sutherland RL (1997) EMS1 amplification can occur independently of CCND1 or INT2 amplification at 11q13 and may identify different phenotypes in primary breast cancer. Oncogene 15:1617-1623
38. 38. Ito I, Yoshimoto M, Iwase T, Watanabe S, Katagiri T, Harada Y, Kasumi F, Yasuda S, Mitomi T, Emi M, Nakamura Y (1995) Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer. Br J Cancer 71:438-441
39. 39. Wellings SR (1980) A hypothesis of the origin of human breast cancer from the terminal ductal lobular unit. Pathol Res Pract 166:515-535