Maximum tolerated doses of methotrexate and 7-hydroxy-methotrexate in a model of acute toxicity in rats

Cancer Chemotherapy and Pharmacology

Volumn 46, Issue 1, 2000, Pages 69-73

  Fuskevåg, Ole Martin ^a   Kristiansen, Christel ^a   Lindal, Sigurd ^a   Aarbakke, Jarle ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

7 Hydroxymethotrexate; Maximum tolerated dose; Methotrexate; Rat

Indexed keywords

7 HYDROXYMETHOTREXATE; DRUG METABOLITE; FOLINIC ACID; METHOTREXATE;

ALKALINIZATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MEGADOSE; DRUG TOLERABILITY; ENDOTHELIUM CELL; HYDRATION; LD 50; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE FUNCTION; URINE PH;

EID: 0033945816     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800000111     Document Type: Article

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