Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

Journal of Human Hypertension

Volumn 14, Issue 6, 2000, Pages 385-387

  Knight, Jo ^a   Gardner, G T B ^a   Clark, A J L ^a   Caulfield, M J ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

African Caribbean; Chromosome 17; Comparative mapping; Essential hypertension; Linkage

Indexed keywords

ADULT; AGED; CHROMOSOME 17Q; CONFERENCE PAPER; ESSENTIAL HYPERTENSION; GENE MAPPING; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MARKER CHROMOSOME; RISK FACTOR; SAINT VINCENT AND THE GRENADINES;

EID: 0033945746     PISSN: 09509240     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jhh.1001025     Document Type: Conference Paper

References (10)

1. Lifton RP. Molecular genetics of human blood pressure variation. Science 1996; 272: 676-680.
2. Luft FC. Molecular genetics of human hypertension. J Hypertens 1998; 16: 1871-1878.
3. Jacob HJ et al. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. Cell 1991; 67: 213-224.
4. Hilbert P et al. Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats. Nature 1991; 353: 521-529.
5. Kreutz R et al. Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10. Proc Natl Acad Sci USA 1995; 92: 8778-8782.
6. Julier C et al. Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. Hum Mol Genet 1997; 6: 2077-2085.
7. Poulter N, Cappuccio F, Chaturvedi N, Cruikshank K. High blood pressure and the African-Caribbean community in the UK. MediNews Limited: England, 1997.
8. Caulfield M et al. Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. J Clin Invest 1995; 96: 687-692.
9. Kruglyak L, Lander ES. Complete multipoint sib-pair analysis of qualitative and quantitative traits [see comments]. Am J Hum Genet 1995; 57: 439-454.
10. Risch N. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 1990; 46: 222-228.