Regioselective derivatization of ouabain with trialkylsilyl reagents and selective oxidation of the unprotected alcohols

Steroids

Volumn 65, Issue 7, 2000, Pages 379-386

  Templeton, John F ^a   Hamlyn, John M ^b   Hamilton, Bruce P ^b   Ayotte, Joanna ^a   Majgier Baranowska, Helena ^a   Lester, Alison ^a   Marat, Kirk ^a   Perreault, Hélène ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac glycoside; Ouabain; Oxidation; Steroid; Trialkylsilylation

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALCOHOL DERIVATIVE; CARDIAC GLYCOSIDE; OUABAIN; SILANE DERIVATIVE;

ARTICLE; CRYSTALLIZATION; DERIVATIZATION; DRUG OXIDATION; DRUG SYNTHESIS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

ALCOHOLS; CARDIOTONIC AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OUABAIN; OXIDATION-REDUCTION; SILANES;

MAMMALIA; STROPHANTHUS GRATUS;

EID: 0033944255     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(00)00096-9     Document Type: Article

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