Bactericidal activity of gentamicin against Enterococcus faecalis in vitro and in vivo

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 8, 2000, Pages 2077-2080

  Lefort, Agnès ^a   Arthur, Michel ^b   Garry, Louis ^a   Carbon, Claude ^a   Courvalin, Patrice ^b   Fantin, Bruno ^a,c  

^a BICHAT HOSPITAL   (France)

^b INSTITUT PASTEUR   (France)

^c BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL COUNT; BACTERIAL ENDOCARDITIS; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; FEMALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; ENDOCARDITIS, BACTERIAL; ENTEROCOCCUS FAECALIS; FEMALE; GENTAMICINS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INJECTIONS, INTRAVENOUS; MICROBIAL SENSITIVITY TESTS; RABBITS;

EID: 0033944013     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.8.2077-2080.2000     Document Type: Article

References (26)

1. Ali, M. Z., and M. B. Goetz. 1997. A meta-analysis of the relative efficacy and toxicity of single daily dosing versus multiple daily dosing of aminoglycosides. Clin. Infect. Dis. 24:796-809.
2. Aslangul, E., M. Baptista, B. Fantin, F. Depardieu, M. Arthur, P. Courvalin, and C. Carbon. 1997. Selection of glycopeptide-resistant mutants of VanB-type Enterococcus faecalis BM4281 in vitro and in experimental endocarditis. J. Infect. Dis. 175:598-605.
3. Bailey, T. C., J. R. Little, B. Littenberg, R. M. Reichley, and W. C. Dunagan. 1997. A meta-analysis of extended-interval dosing versus multiple daily dosing of aminoglycosides. Clin. Infect. Dis. 24:786-795.
4. Blaser, J., and C. Konig. 1995. Once-daily dosing of aminoglycosides. Eur. J. Clin. Microbiol. Infect. Dis. 14:1029-1038.
5. Blaser, J., B. B. Stone, M. C. Groner, and S. H. Zinner. 1987. Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance. Antimicrob. Agents Chemother. 31:1054-1060.
6. Craig, W. A. 1998. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin. Infect. Dis. 26:1-10.
7. Davis, S. D., and A. Iannetta. 1972. Influence of serum and calcium on the bactericidal activity of gentamicin and carbenicillin on Pseudomonas aeruginosa. Appl. Microbiol. 23:775-779.
8. Demczar, D. J., A. N. Nafziger, and J. S. Bertino. Jr. 1997. Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing. Antimicrob. Agents Chemother. 41:1115-1119.
9. Gold, M. J., J. Calmon, M. Wendeler, M. E. Levison, and C. C. Johnson. 1991. Synergistic bactericidal activity of rat serum with vancomycin against enterococci. J. Infect. Dis. 163:1358-1361.
10. Harvey, B. S., C. J. Baker, and M. S. Edwards. 1992. Contributions of complement and immunoglobulin to neutrophil-mediated killing of enterococci. Infect. Immun. 60:3635-3640.
11. Hyatt, J. M., P. S. McKinnon, G. S. Zimmer, and J. J. Schentag. 1995. The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents. Clin. Pharmacokinet. 28:143-160.
12. Jacob, A. E., and S. J. Hobbs. 1974. Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. J. Bacteriol. 117:360-372.
13. Leclercq, R. 1997. Enterococci acquire new kinds of resistance. Clin. Infect. Dis. 24(Suppl. 1):80-84.
14. Lefort, A., M. Baptista, B. Fantin, F. Depardieu, M. Arthur, C. Carbon, and P. Courvalin. 1999. Two-step acquisition of resistance to the teicoplanin-gentamicin combination by VanB-type Enterococcus faecalis in vitro and in experimental endocarditis. Antimicrob. Agents Chemother. 43:476-482.
15. Leggett, J. E., and W. A. Craig. 1989. Enhancing effect of serum ultrafiltrate on the activity of cephalosporins against gram-negative bacilli. Antimicrob. Agents Chemother. 33:35-40.
16. Moellering, R. C., Jr., and A. N. Weinberg. 1971. Studies on antibiotic synergism against enterococci. II. Effect of various antibiotics on the uptake of 14C-labeled streptomycin by enterococci. J. Clin. Investig. 50:2580-2584.
17. Moore, R. D., P. S. Lietman, and C. R. Smith. 1987. Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J. Infect. Dis. 155:93-99.
18. Moore, R. D., C. R. Smith, and P. S. Lietman. 1984. The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia. J. Infect. Dis. 149:443-448.
19. Moore, R. D., C. R. Smith, and P. S. Lietman. 1984. Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. Am. J. Med. 77:657-662.
20. Noone, P., T. M. Parsons, J. R. Pattison, R. C. Slack, D. Garfield-Davies, and K. Hughes. 1974. Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis. Br. Med. J. i:477-481.
21. Quintiliani, R., Jr., and P. Courvalin. 1994. Conjugal transfer of the vancomycin resistance determinant vanB between enterococci involves the movement of large genetic elements from chromosome to chromosome. FEMS Microbiol. Lett. 119:359-364.
22. Steel, R. G. D., and J. H. Tovrie. 1980. Multiple comparisons, p. 172-194. In Principles and procedures of statistics: a biometrical approach. McGraw-Hill Book Co., New York, N.Y.
23. Steers, E., E. L. Foltz, B. S. Graves, and J. Riden. 1959. An inocula replicating apparatus for routine testing of bacterial susceptibility to antibiotics. Antibiot. Chemother. (Basel) 9:307-311.
24. Sullam, P. M., M. G. Täuber, C. J. Hackbarth, and M. A. Sande. 1985. Antimicrobial activity of gentamicin in experimental enterococcal endocarditis. Antimicrob. Agents Chemother. 27:224-226.
25. Traub, W. H., and J. C. Sherris. 1970. Studies on the interaction between serum bactericidal activity and antibiotics in vitro. Chemotherapy 15:70-83.
26. Traub, W. H., M. Spohr, and D. Bauer. 1986. Streptococcus faecalis: in vitro susceptibility to antimicrobial drugs, single and combined, with and without defibrinated human blood. Chemotherapy 32:270-285.