Parental origin and phenotype of triploidy in spontaneous abortions: Predominance of diandry and association with the partial hydatidiform mole

American Journal of Human Genetics

Volumn 66, Issue 6, 2000, Pages 1807-1820

  Zaragoza, Michael V ^a   Surti, Urvashi ^c   Redline, Raymond W ^b   Millie, Elise ^a   Chakravarti, Aravinda ^a   Hassold, Terry J ^a,d  

^a Center for Human Genetics   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME STRUCTURE; GENETIC ANALYSIS; GENETIC MARKER; GESTATIONAL AGE; HUMAN; HYDATIDIFORM MOLE; MAJOR CLINICAL STUDY; MEIOSIS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SPONTANEOUS ABORTION; TRIPLOIDY;

EID: 0033941722     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302951     Document Type: Article

References (36)

1. Angell RR, Sandison A, Bain AD (1984) Chromosome variation in perinatal mortality: a survey of 500 cases. J Med Genet 21:39-44
2. Antonarakis SE (1991) Parental origin of the extra chromosome in trisomy 21 as indicated by analysis of DNA polymorphisms. Down Syndrome Collaborative Group. N Engl J Med 324:872-876
3. Beatty RA (1957) Parthenogenesis and polyploidy in mammalian development. University Press, Cambridge, UK
4. Chakravarti A (1989) The probability of detecting the origin of non-disjunction of autosomal trisomies. Am J Hum Genet 44:639-645
5. Chakravarti A, Slaugenhaupt SA (1987) Methods for studying recombination on chromosomes that undergo nondisjunction. Genomics 1:35-42
6. Dietzsch E, Ramsay M, Christianson AL, Henderson BD, de Ravel TJL (1995) Maternal origin of extrahaploid set of chromosomes in third trimester triploid fetuses. Am J Med Genet 58:360-364
7. Don RH, Cox PT, Wainwright BJ, Baker K, Mattick JS (1991) "Touchdown" PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res 19:4008
8. Eppig JJ Schultz RM, O'Brien M, Chesnel F (1994) Relationship between the developmental programs controlling nuclear and cytoplasmic maturation of mouse oocytes. Dev Biol 164:1-9
9. French FE, Bierman JM (1962) Probabilities of fetal mortality. Public Health Service Rep 77:835-847
10. Funaki K, Mikmo K (1980) Giant diploid oocytes as a cause of digynic triploidy in mammals. Cytogenet Cell Genet 28: 158-168
11. Hassold T, Chen N, Funkhouser J, Jooss T, Manuel B, Matsura J, Matsuyama A, et al (1980) A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet 44:151-164
12. Hoffner L, Shen-Schwarz S, Deka R, Chakravarti A, Surti U (1992) Genetics and biology of human ovarian teratomas. III. Cytogenetics and origins of malignant ovarian germ cell tumors. Cancer Genet Cytogenet 62:58-65
13. Hook EB, Hamerton JL (1977) The frequency of chromosome abnormalities detected in consecutive newborn studies. In: Hook EB, Porter IH (eds) Population cytogenetics studies in humans. Academic Press, New York, pp 63-79
14. Jacobs PA, Angell RR, Buchanan IM, Hassold TJ, Matsuyama AM, Manual B (1978) The origin of human triploids. Ann Hum Genet 42:49-57
15. Jacobs PA, Hassold T (1995) The origin of numerical chromosome abnormalities. Adv Genet 33:101-133
16. Jacobs PA, Morton NE (1977) Origin of human trisomies and polyploids. Hum Hered 27:59-72
17. Jacobs PA, Szulman AE, Funkhouser J, Matsuura JS, Wilson CC (1982) Human triploidy: relationship between parental origin of the additional haploid complement and development of partial hydatidiform mole. Ann Hum Genet 46: 223-231
18. Kajii T, Ohama K (1977) Androgenetic origin of hydatidiform mole. Nature 268:633-634
19. Kono T, Obata Y, Yoshimzu T, Nakahara T, Carroll J (1996) Epigenetic modifications during oocyte growth correlates with extended parthenogenetic development in the mouse. Nat Genet 13:91-94
20. Lane SA, Taylor GR, Ozols B, Quirke P (1993) Diagnosis of complete molar pregnancy by microsatellites in archival material. J Clin Pathol 46:346-348
21. Lawler SD, Fisher RA, Dent J (1991) A prospective genetic study of complete and partial hydatidiform moles. Am J Obstet Gynecol 164:1270-1277
22. Lorber BJ, Grantham M, Peters J, Willard HF, Hassold TJ (1992) Nondisjunction of chromosome 21: comparisons of cytogenetic and molecular studies of the meiotic stage and parent of origin. Am J Hum Genet 51:1265-1276
23. Martin RH, Spriggs E, Ko E, Rademaker AW (1995) The relationship between paternal age sex ratios, and aneuploidy frequencies in human sperm, as assessed by multicolor FISH. Am J Hum Genet 57:1395-1399
24. McFadden DE, Kwong LC, Yam IYL, Langlois S (1993) Parental origin of triploidy in human fetuses: evidence for genomic imprinting. Hum Genet 92:465-469
25. McFadden DE, Langlois S (1997) Meiotic origin of triploidy. Medizinische Genetik Suppl 9:525
26. McFadden DE, Pantzar JT (1996) Placental pathology of triploidy. Hum Path 27:1018-1020
27. McFadden DE, Pantzar JT, Langlois S (1994) Parental origin of triploidy-digyny not diandry. Mod Pathol 7:5P
28. Miny P, Koppers B, Dworniczak B, Bogdanova N, Holzgreve W, Tercanli S, Basaran S, et al (1995) Parental origin of the extra haploid chromosome set in triploidies diagnosed prenatally. Am J Med Genet 57:102-106
29. Niebuhr E (1974) Triploidy in man. Humangenetik 21: 103-125
30. Obata Y, Kaneko-Ishino T, Koide T, Takai Y, Ueda T, Domeki I, Shiroishi T, et al (1998) Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development 125: 1553-1560
31. Procter SE, Gray ES, Watt JL (1984) Triploidy, partial mole and dispermy: an investigation of 12 cases. Clin Genet 26: 46-51
32. Redline RW, Hassold T, Zaragoza MV (1998) Prevalance of the partial molar phenotype in triploidy of maternal and paternal origin. Hum Pathol 29:505-511
33. Sherald J, Bean C, Bove B, DelDuca V, Esterly KI, Karcsh HJ, Munshi G, et al (1986) Long survival in a 69, XXY triploid male. Am J Med Genet 25:307-312
34. Szulman AE, Surti U (1978) The syndromes of hydatidiform mole. Am J Obstet Gynecol 132:20-27
35. Uchida IA, Freeman VCP (1985) Triploidy and chromosomes. Am J Obstet Gynecol 151:65-69
36. Warburton D, Byrne J, Canki N (1991) Chromosome anomalies and prenatal development: an atlas. Oxford University Press, New York