Metabolism of ticlopidine by activated neutrophils: Implications for ticlopidine-induced agranulocytosis

Drug Metabolism and Disposition

Volumn 28, Issue 7, 2000, Pages 726-730

  Liu, Zhao Chao ^a   Uetrecht, Jack P ^b  

^a APPLIED BIOSYSTEMS   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLUTATHIONE; HYDROGEN PEROXIDE; HYPOCHLORITE; MYELOPEROXIDASE; OXIDIZING AGENT; THIOPHENE DERIVATIVE; TICLOPIDINE;

AGRANULOCYTOSIS; APLASTIC ANEMIA; ARTICLE; DRUG CONJUGATION; DRUG METABOLISM; DRUG OXIDATION; HUMAN; LEUKOCYTE ACTIVATION; MASS SPECTROMETRY; PRIORITY JOURNAL;

AGRANULOCYTOSIS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; GLUTATHIONE; HUMANS; HYPOCHLOROUS ACID; NEUTROPHIL ACTIVATION; NEUTROPHILS; OXIDATION-REDUCTION; TICLOPIDINE;

EID: 0033941434     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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