Low propensity of conventional antiepileptic drugs for interaction with felbamate against maximal electroshock-induced seizures in mice

Journal of Neural Transmission

Volumn 107, Issue 7, 2000, Pages 733-743

  Borowicz, K K ^a   Stasiuk, G ^a   Teter, J ^a   Kleinrok, Z ^a   Gasior, M ^a,c   Czuczwar, S J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

^c NIDA Addiction Research Center   (United States)

Author keywords

Antiepileptic drugs; Drug interactions; Electroshock maximal; Felbamate; Seizures

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; FELBAMATE; PHENOBARBITAL; PHENYTOIN; VALPROATE MAGNESIUM; VALPROIC ACID;

ALTERNATING CURRENT; ANIMAL EXPERIMENT; APLASTIC ANEMIA; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; CONVULSION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; ELECTRIC SHOCK; ELECTRODE; EXTENSOR MUSCLE; FEMALE; HINDLIMB; IMMUNOFLUORESCENCE; LIVER TOXICITY; LONG TERM MEMORY; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TASK PERFORMANCE;

ANIMALS; ANTICONVULSANTS; AVOIDANCE LEARNING; BRAIN; DRUG INTERACTIONS; ELECTROSHOCK; FEMALE; MICE; MOTOR SKILLS; PROPYLENE GLYCOLS; SEIZURES;

EID: 0033941371     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020070055     Document Type: Article

References (38)

1. Adusumalli VE, Choi YM, Romanyshyn NA (1993) Isolation and identification of 3-carbamoyloxy-2-phenylpropionic acid as a major human urinary metabolite of felbamate. Drug Metab Disp 21: 710-716
2. Albani F, Theodore WH, Washington P, Devinsky O, Bromfield E, Porter RJ, Nice FJ (1991) Effect of felbamate on plasma levels of carbamazepine and its metabolites. Epilepsia 32: 130-132
3. Bibileishvili S (1997) Treatment of epilepsy: monotherapy or polytherapy? Are we going back? Epilepsia 38 [Suppl 3]: 82
4. Boissier JR, Tardy J, Diverres JC (1960) Une nouvelle methode simple pour explorer l'action'tranquilisante: le test de la cheminee. Med Exp (Basel) 3: 81-84
5. 6-2-(4-Aminophenyl) ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs. Eur J Pharmacol 327: 125-133
6. Borowicz KK, Kleinrok Z, Czuczwar SJ (1997b) Influence of 7-nitroindazole on the anticonvulsive action of conventional antiepileptic drugs. Eur J Pharmacol 331: 127-132
7. Bourgeois B, Leppik IE, Sackellares JC (1993) Felbamate: a double-blind controlled trial in patients undergoing presurgical evaluation of partial seizures. Neurology 43: 693-696
8. Czuczwar SJ, Kleinrok Z (1990) Modulation of the protective efficacy of common antiepileptic drugs by xanthine derivatives: implications for the clinical use of xanthines in epileptic patients. Pharmacol Res 22: 661-665
9. Czuczwar SJ, Gasior M, Janusz W, Kleinrok Z (1990) Influence of different methylxanthines on the anticonvulsant action of common antiepileptic drugs in mice. Epilepsia 33: 318-323
10. Czuczwar SJ, Gasior M, Janusz W, Kleinrok Z (1992) Influence of flunarizine, nicardipine and nimodipine on the anticonvulsant activity of different antiepileptic drugs in mice. Neuropharmacology 31: 1179-1183
11. Czuczwar SJ, Kleinrok Z, Turski WA (1996a) Interaction of calcium channel blockers and excitatory amino acid antagonists with conventional antiepileptic drugs. CNS Drug Rev 2: 452-467
12. Czuczwar SJ, Turski WA, Kleinrok Z (1996b) Interactions of excitatory amino acid antagonists with conventional antiepileptic drugs. Metab Brain Dis 11: 143-152
13. Czuczwar SJ, Świader M, Pilip S, Gasior M, Kleinrok Z (1999) Influence of a novel antiepileptic drug, topiramate, on the anticonvulsive activity of conventional antiepileptics in mice. Naunyn Schmiedebergs Arch Pharmacol [Suppl] 359: R96
14. Deckers CLP, Hekster YA, Keyser A (1997) Reappraisal of polytherapy in epilepsy: a critical review of drug load and adverse effects. Epilepsia 38: 570-575
15. Devinsky O, Faught RE, Wilder BJ (1995) Efficacy of felbamate monotherapy in patients undergoing presurgical evaluation of partial seizures. Epilepsy Res 20: 241-246
16. De Romanis F, Sopranzi N (1997) Felbamate: a long-term study in subjects with refractory epilepsy. Clin Ter 148: 83-87
17. Fraught E, Sachdeo RC, Remler MP (1993) Felbamate monotherapy for partial-onset seizures: an active control trial. Neurology 43: 688-692
18. Gasior M, Borowicz K, Buszewicz G, Kleinrok Z, Czuczwar SJ (1996) Anticonvulsant activity of phenobarbital and valproate against maximal electroshock in mice during chronic treatment with caffeine and caffeine discontinuation. Epilepsia 37: 262-268
19. 2+ channel modulators against experimental seizures in mice. Eur J Pharmacol 352: 207-214
20. Gordon R, Gels M, Diamantis W, Sofia RD (1991 ) Interaction of felbamate and diazepam against maximal electroshock seizures and chemoconvulsants in mice. Pharmacol Biochem Behav 40: 109-113
21. Gordon R, Gels M, Wichmann J, Diamantis W, Sofia RD (1993) Interaction of felbamate with several other antiepileptic drugs against seizures induced by maximal electroshock in mice. Epilepsia 34: 364-371
22. Harden CL (1994) New antiepileptic drugs. Neurology 44: 787-795
23. Kleckner NW, Glazewski JC, Chen CC, Moscrip TD (1999) Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action. J Pharmacol Exp Ther 289: 886-894
24. Krämer G (1997) The limitations of antiepileptic drug monotherapy. Epilepsia 38 [Suppl 5]: S9-S13
25. Litchfield JT, Wilcoxon F (1949) A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96: 99-113
26. Perucca E (1996) The new generation of antiepileptic drugs: advantages and disadvantages. Br J Clin Pharmacol 42: 531-543
27. Schimdt D (1996) Modern management of epilepsy: rational polytherapy. Baillieres Clin Neurol 5: 757-763
28. Shank PR, Gardocki JF, Vaught JL (1994) Topiramate: preclinical evaluation of a structurally novel anticonvulsant. Epilepsia 35: 450-460
29. 14C]felbamate in healthy men. Epilepsia 31: 642
30. Swinyard EA, Sofia RD, Kupferberg HJ (1986) Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats. Epilepsia 27: 27-34
31. Theodore WH, Raubertas RF, Porter RJ (1991) Felbamate: clinical trial for complex partial seizures. Epilepsia 32: 392-297
32. Venault P, Chapouthier G, De Carvalho LP, Simiand J, Morre M, Dodd RH, Rossier J (1986) Benzodiazepines impair and beta-carbolines enhance performance in learning and memory task. Nature 321: 864-866
33. Wagner ML, Graves NM, Marienau K, Holmes GB, Remmel RP, Leppik IE (1991) Discontinuation of phenytoin and carbamazepine in patients receiving felbamate. Epilepsia 32: 398-406
34. Wagner ML, Remmel RP, Graves NM, Leppik IE (1993) Effect of felbamate on carbamazepine and its major metabolites. Clin Pharmacol Ther 53: 536-543
35. Wlaź P, Löscher W (1997) Anticonvulsant activity of felbamate in amygdala kindling model of temporal lobe epilepsy in rats. Epilepsia 38: 167-172
36. Wlaź P, Roliński Z, Kleinrok Z, Czuczwar SJ (1993) Influence of chronic aminophylline on the anticonvulsant efficacy of phenobarbital and valproate in mice. Epilepsia 34: 385-389
37. Yang JT, Adusumalli VE, Wong KK (1991) Felbamate metabolism in the rat, rabbit and dog. Drug Metab Disp 19: 1126-1134
38. Żarnowski T, Kleinrok Z, Turski WA, Czuczwar SJ (1994) The NMDA antagonist procyclidine, but not ifenprodil, enhances the protective efficacy of common antiepileptics against maximal electroshock-induced seizures in mice. J Neural Transm 97: 1-12