Comparison of the genetic alterations in two epithelial collision tumors of the uterine cervix. A report of two cases

International Journal of Gynecological Pathology

Volumn 19, Issue 3, 2000, Pages 225-230

  Kersemaekers, Anne Marie F ^a   Van De Vijver, Marc J ^a   Fleuren, Gert Jan ^a  

^a Department of Pathology ^*  (Netherlands)

Author keywords

Clonality; Uterus Cervix Collision Loss of heterozygosity Double tumors Adenosquamous

Indexed keywords

ADENOSQUAMOUS CARCINOMA; ADULT; ARTICLE; CHROMOSOME 11Q; CHROMOSOME 15; CHROMOSOME 17Q; CHROMOSOME 3; CHROMOSOME 6Q; DIFFERENTIAL DIAGNOSIS; ENDOMETRIUM CARCINOMA; EPITHELIUM TUMOR; FEMALE; GENE FREQUENCY; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0033936301     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004347-200007000-00005     Document Type: Article

References (24)

1. Abeln EC, Smit VT, Wessels JW, de Leeuw WJ, Cornelisse CJ, Fleuren GJ. Molecular genetic evidence for the conversion hypothesis of the origin of malignant mixed mullerian tumours. J Pathol 1997;183:424-31.
2. Yajima A, Fukuda M, Noda K. Histopathological findings concerning the morphogenesis of mixed carcinoma of the uterine cervix. Gynecol Oncol 1984;18:157-64.
3. Choo YC, Naylor B. Coexistent squamous cell carcinoma and adenocarcinoma of the uterine cervix. Gynecol Oncol 1984;17: 168-74.
4. Christopherson WM, Nealon N, Gray LA. Noninvasive precursor lesions of adenocarcinoma and mixed adenosquamous carcinoma of the cervix uteri. Cancer 1979;44:975-83.
5. Dougherty CM, Cotton N. Mixed squamous-cell and adenocarcinoma of the cervix. Combined, adenosquamous, and mucoepidermoid types. Cancer 1964;17:1132-43.
6. Lauchlan SC, Penner DW. Simultaneous adenocarcinoma in situ and epidermoid carcinoma in situ. Report of two cases. Cancer 1967;20:2250-4.
7. Mitra AB, Murty VVVS, Li RG, Pratap M, Luthra UK, Chaganti RSK. Allelotype analysis of cervical carcinoma. Cancer Res 1994; 54:4481-7.
8. Mullokandov MR, Kholodilov NG, Atkin NB, Burk RD, Johnson AB, Klinger HP. Genomic alterations in cervical carcinoma: losses of chromosome heterozygosity and human papilloma virus tumor status. Cancer Res 1996;56:197-205.
9. Rader JS, Kamarasova T, Huettner PC, Li L, Li Y, Gerhard DS. Allelotyping of all chromosomal arms in invasive cervical cancer. Oncogene 1996;13:2737-41.
10. Kersemaekers AMF, Kenter GG, Hermans J, Fleuren GJ, van de Vijver MJ. Allelic loss and prognosis in carcinoma of the uterine cervix. Int J Cancer (Pred Oncol) 1998;79:411-7.
11. Abeln EC, Corver WE, Kuipers-Dijkshoorn NJ, Fleuren GJ, Cornelisse CJ. Molecular genetic analysis of flow-sorted ovarian tumour cells: improved detection of loss of heterozygosity. Br J Cancer 1994;70:255-62.
12. Kersemaekers AMF, Hermans J, Fleuren GJ, van de Vijver MJ. Loss of heterozygosity for defined regions on chromosomes 3, 11 and 17 in carcinoma of the uterine cervix. Br J Cancer 1998;77: 192-200.
13. Devilee P, Schothorst EM, Bardoel AFJ, et al. Allelotype of head and neck paragangliomas: allelic imbalance is confined to the long arm of chromosome 11, the site of the predisposing locus PGL. Genes Chromosomes Cancer 1994;11:71-8.
14. Tieben LM, Schegget JT, Minnaar RP, et al. Detection of cutaneous and genital HPV types in clinical samples by PCR using consensus primers. J Virolog Meth 1993;42:265-80.
15. Greer CE, Peterson SL, Kiviat NB, Manos MM. PCR amplification from paraffin-embedded tissues: effects of fixative and fixation time. American J Clin Pathol 1991;95:117-24.
16. Roda-Husman AM, Walboomers JMM, Van den Brule AJC, Meijer CJLM, Snijders PJF. The use of general primers GP5 and GP6 elongated at their 3' ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR. J Gen Virol 1995;76:1057-62.
17. Bauer HM, Greer CE, Manos MM. Determination of genital human papillomavirus infection by consensus PCR amplification. In: Herrington CS, McGee JO, eds. Diagnostic Molecular Pathology. A Practical Approach. Oxford: Oxford University Press, 1992: 131-52.
18. Manos MM, Wright DK, Lewis AJ, Broker TR, Wolinski SM. The use of polymerase chain reaction amplification for the detection of genital human papillomaviruses. In: Furth M, Greaves M, eds. Molecular Diagnostics of Human Cancer, Cancer cells. Cold Spring Harbor, NY: Cold Spring Harbor Press. 1989:209-14.
19. Jacobs IJ, Kohler MF, Wiseman RW, et al. Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation. J Natl Cancer Inst 1992;84:1793-8.
20. Hampton GM, Penny LA, Baergen RN, et al. Loss of heterozygosity in cervical carcinoma: Subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24. Proc Natl Acad Sci USA 1994;91:6953-7.
21. Bethwaite PB, Koreth J, Herrington CS, McGee JO, Loss of heterozygosity occurs at the D11S29 locus on chromosome 11q23 in invasive cervical carcinoma. Br J Cancer 1995;71:814-8.
22. Wistuba II, Montellano FD, Milchgrub S, et al. Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma. Cancer Res 1997;57:3154-8.
23. Rader JS, Gerhard DS, O'Sullivan MJ, Li Y, Li L, Liapis H, Huettner PC. Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p. Genes Chromosomes Cancer 1998;22: 57-65.
24. Larson AA, Liao SY, Stanbridge EJ, Cavenee WK, Hampton GM. Genetic alterations accumulate during cervical tumorigenesis and indicate a common origin for multifocal lesions. Cancer Res 1997; 57:4171-6.