Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides

Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2000, Pages 2430-2437

  Zhu, Zhijian ^a,b   Lippa, Blaise ^a,b   Drach, John C ^b   Townsend, Leroy B ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMO 1 (BETA DEXTRO RIBOFURANOZYL)BENZIMIDAZOLE; 2,5,6 TRICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)BENZIMIDAZOLE; 2,6,7 TRICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)IMIDAZOLE [4,5 B]QUINOLINE; BENZIMIDAZOLE DERIVATIVE; NUCLEOSIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOMEGALOVIRUS; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1;

ANTIVIRAL AGENTS; BENZIMIDAZOLES; CELL DIVISION; CELL LINE; CYTOMEGALOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HERPESVIRUS 1, HUMAN; HUMANS; IMIDAZOLES; INHIBITORY CONCENTRATION 50; PLAQUE ASSAY; QUINOLINES; RIBONUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033935788     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990290y     Document Type: Article

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