Role of loop D of the α7 nicotinic acetylcholine receptor in its interaction with the insecticide imidacloprid and related neonicotinoids

British Journal of Pharmacology

Volumn 130, Issue 5, 2000, Pages 981-986

  Matsuda, Kazuhiko ^a   Shimomura, Masaru ^a   Kondo, Yumi ^a   Ihara, Makoto ^a   Hashigami, Kaori ^a   Yoshida, Naofumi ^a   Raymond, Valérie ^b   Mongan, Nigel P ^b   Freeman, John C ^b   Komai, Koichiro ^a   Sattelle, David B ^b  

^a KINKI UNIVERSITY   (Japan)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Imidacloprid; Negative subsite mutations; Neonicotinoids; Nicotinic acetylcholine receptor; Nitenpyram; 7 subunit

Indexed keywords

ACETYLCHOLINE; EPIBATIDINE; IMIDACLOPRID; INSECTICIDE; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; CHICKEN; FEMALE; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; XENOPUS LAEVIS;

EID: 0033935298     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703374     Document Type: Article

References (17)

1. ARIAS, H.R. (1997). Topology of ligand binding sites on the meotinic acetylcholine receptor. Brain Res. Rev., 25, 13-191.
2. BAI, D., LUMMIS, S.C.R , LEICHT. B., BREER, H * SATTTLLE, D.B. (1991). Actions of imidacloprid and a related nitromethylene on cholinergic receptors of an identified insect motor neuron. Pestic. Sci., 33, 197-204.
3. BUCKINGHAM, S.D., HOSIE, A.M., ROUSH, R T. & SATTTLLEE, D.B. (1994). Actions of agonists and convulsant antagonists on a Drosophila melanogaster GABA receptor (Rd1) homo-oligomer expressed in Xenopus oocytes. Neurosci. Lett., 181, 137-140.
4. COUTURIER, S., BERTRAND, D., MATTER, J-M., HERNANDEZ, M.-C., BERTRAND, S., MILLAR, N., VALERA, S., BARKAS, T. & BALLIVET, M (1990). A neuronal nicotinic acetylcholine receptor subunit (z7) is developmentally regulated and forms a homo-oligomeric channel blocked by z-BTX. Neuron, 5, 847-856.
5. HIGUCHI, R. (1989), Using PCR to engineer DNA. In PCR technology. ed. Erlich, H.A. pp. 61-70. New York: Stockton Press.
6. KAGABU, S., YOKOYAMA, K.. IWATA, K & TANAKA, M. (1998). Imidacloprid and related compounds: Structure and water solubility of N-alkyl derivatives of imidacloprid. Biosci. Biotechnol. Biochem., 62, 1216-1224.
7. KARLIN, A. & AKABAS, M.H (1995). Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron, 15, 1231-1244.
8. KUSANO, K., MILEDI, R. & STINNAKRE, J. (1977). Acetylcholine receptors in the oocyte membrane. Nature, 270, 739-741.
9. 3H]imidacloprid in the insect acetylcholine receptor. Pestic. Biochem. Physiol., 46, 40-46.
10. 45Ca efflux kinetics. Pflügers Arch., 417, 391-397.
11. MATSUDA, K., BUCKINGHAM, S.D., FREEMAN, J.C., SQUIRE, M.D., BAYLIS, H A. & SATTTLLE, D.B. (1998). Effects of the α subunit on imidacloprid sensitivity of recombinant nicotinic acetylcholine receptors. Br. J. Pharmacol., 123, 518-524.
12. NAGATA, K., AISTRUP, J.L., SONG, J.-H. & NARAHASHI, T. (1996). Subconductance-state currents generated by imidacloprid at the nicotinic acetylcholine receptor in PC12 cells. NeuroReport, 7, 1025-1028.
13. SWICK, A.G., JANICOT, M., CHENEVAL-KASTELIC, T., MCLENITHAN, J.C. & LANE, D.M. (1992). Promoter-cDNA-directed heterologous protein expression in Xenopus laevis oocytes. Proc. Natl. Acad. Sci. U.S.A., 89, 1812-1816.
14. TOMIZAWA, M., LATLI, B. & CASIDA, J.E. (1996). Novel neonicotinoid-agarose affinity column for Drosophila and Musca nicotinic acetylcholine receptors. J. Neurochem., 67, 1669-1676.
15. TOMIZAWA, M. & YAMAMOTO, I. (1992). Binding of nicotinoids and the related compounds to the insect nicotinic acetylcholine receptor. J. Pestic. Sci., 17, 231-236.
16. TOMIZAWA, M. & YAMAMOTO, I. (1993). Structure-activity relationships of nicotinoids and imidacloprid analogs. J. Pestic. Sci., 18, 91-98.
17. YAMAMOTO, I., YABUTA, G., TOMIZAWA, M., SAITO, T., MIYAMOTO, T & KAGABU, S. (1995). Molecular mechanism for selective toxicity of nicotinoids and neonicotinoids. J. Pestic. Sci., 20, 33-40.